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How do doctors and researchers measure eczema?

Key Takeaway: The article discusses the Investigator's Static Global Assessment (ISGA) scale, which measures the severity of eczema from 0 to 4. A score of 0 indicates clear skin, while a score of 4 represents severe eczema. Effective treatments aim to reduce scores by at least 2 points, ideally achieving a score of 0-1. The evaluation period varies depending on the treatment type.

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POSITIVE FACTORS

  • The ISGA scale provides a clear framework for assessing eczema severity.
  • Successful therapies are defined by significant score reductions.
  • Educational efforts aim to empower patients and caregivers.

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GX-03
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Full Press Release Details

We are all numbers when it comes to eczema.
0-4 to be exact.
The ISGA, or Investigator’s Static Global Assessment , is a five-point scale that provides a clinical assessment of atopic dermatitis severity ranging from 0 to 4.
• 0 indicates clear
• 1 is almost clear
• 2 is mild
• 3 is moderate
• 4 indicates severe.
The lower the score, the better. A well-managed eczema patient is a patient at a 0-1 on the ISGA scale, and a successful therapy is typically regarded as one that safely and effectively reduces scores at least 2 points, ideally to an ISGA of 0-1. The length of time is very much product and study dependent; steroids are often evaluated over as little as 4 weeks while injectable biologics can be evaluated over 16 weeks.
As I like to teach via example, please see this public link for reference. Inside, you will see study results from a popular non-steroid topical indicated for mild to moderate eczema, or eczema that begins at an ISGA between 1 and 3.
Watch for more updates in the coming days. There’s a reason I’m teaching you this beyond just loving to create more educated patients, caregivers, and investors.

Frequently Asked Questions

What does the ISGA scale measure?

The ISGA scale measures the severity of eczema from 0 to 4.

What does a score of 0 on the ISGA indicate?

A score of 0 indicates clear skin, meaning no eczema.

How is a successful eczema therapy defined?

A successful therapy typically reduces the ISGA score by at least 2 points.

What is the evaluation period for steroid treatments?

Steroid treatments are often evaluated over a period of 4 weeks.

How long are injectable biologics evaluated?

Injectable biologics can be evaluated over 16 weeks.

Last updated: Jun 19, 2024