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Trevi Therapeutics to Participate in Upcoming Investor and Healthcare Events Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine...

Key Takeaway: Trevi Therapeutics, Inc. has announced its participation in several upcoming investor and healthcare events, emphasizing their investigational therapy Haduvio™ for chronic cough. Notably, two abstracts regarding ongoing clinical trials for Haduvio have been accepted for presentation at the Thirteenth London International Cough Symposium. The company aims to highlight its advancements in treating chronic cough associated with idiopathic pulmonary fibrosis and refractory chronic cough, conditions currently lacking approved therapies. Key representatives will attend multiple conferences in July and August to discuss these developments and engage with stakeholders.
Price reaction · baseline $2.89 (2024-07-01 close) · hit after-hours · clean, no other TRVI news in the window
day 0 close
-7.3%
day 1 · peak
-7.6%
day 3
-5.9%

Market Sentiment Analysis

POSITIVE FACTORS

  • Trevi Therapeutics is preparing to present research at significant medical conferences.
  • Accepted abstracts showcase ongoing clinical trials for innovative cough treatments.
  • Haduvio has potential applications for chronic cough conditions where there are currently no approved therapies.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+84%
120-day peak, hindsight
Typical move
11.5%
average across 3 past catalysts
Cash runway
~54 mo
Minimal dilution risk
Lead asset
nalbuphine
Phase 2 · Prurigo Nodularis

Full Press Release Details

Two abstracts accepted for oral presentation at the 13 th London International Cough Symposium
NEW HAVEN, Conn. , July 2, 2024 /PRNewswire/ -- Trevi Therapeutics, Inc. (Nasdaq: TRVI ), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for the treatment of chronic cough in idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC), today announced that senior management will be attending investor and medical conferences in July and August. In addition, Trevi is pleased to announce that abstracts on the ongoing Phase 2b CORAL and Phase 2a RIVER trials were accepted for presentation at the Thirteenth London International Cough Symposium.
Leerink Partners Therapeutics Forum: I&I and Metabolism July 9-10, 2024 , Boston, MA Trevi Representatives: Jennifer Good, President and CEO, and Lisa Delfini , CFO
The Thirteenth London International Cough Symposium July 18-19, 2024 , London, UK Abstract 1: Sample Size Reestimation in an Ongoing Dose-ranging Study of Nalbuphine Extended-release For Cough in Idiopathic Pulmonary Fibrosis (CORAL) Abstract 2: Efficacy And Safety of Nalbuphine Extended-release Tablets for the Treatment of Refractory Chronic Cough: A Phase 2 Trial in Progress (RIVER) Symposium Focus : The Thirteenth London International Cough Symposium brings together clinicians, scientists, and researchers in the field of cough from across the world. The purpose of this symposium is to share, review and discuss emerging ideas, novel approaches, and clinical research advancements in the management of chronic cough. Registration details
Oppenheimer's Biotech in the Berkshires August 5-7, 2024 , Lenox, MA Trevi Representative: Jennifer Good , President and CEO
Stifel 2024 Biotech Summer Summit August 12-14, 2024 , Newport RI Trevi Representatives: Jennifer Good , President and CEO, and Farrell Simon, CCO
About Trevi Therapeutics, Inc. Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for the treatment of chronic cough in idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC). Haduvio is a dual ĸ-opioid receptor agonist and µ-opioid receptor antagonist that works both centrally in the brain as well as peripherally in the lungs and has the potential for a synergistic antitussive effect to treat chronic cough.
The impact of chronic cough is significant and often leads to a decline in patients' social, physical, and psychological quality of life. In IPF, chronic cough may lead to worsening disease and may be associated with a higher risk of progression, death, or need for lung transplant. There are no approved therapies for the treatment of chronic cough in IPF and current treatment options provide minimal relief to patients. RCC affects up to 10% of the adult population, and Haduvio's expansion into RCC has the potential to reach patients suffering from moderate to severe chronic cough. There are also no approved therapies for RCC in the US.
Parenteral nalbuphine is not scheduled by the U.S. Drug Enforcement Agency. Trevi intends to propose Haduvio as the trade name for oral nalbuphine ER. Its safety and efficacy have not been evaluated by any regulatory authority.
For more information, visit www.TreviTherapeutics.com and follow Trevi on X (formerly Twitter) and LinkedIn .

Frequently Asked Questions

What is Haduvio™ developed by Trevi Therapeutics?

Haduvio™ is an investigational therapy using oral nalbuphine ER for chronic cough treatment.

What are the ongoing trials associated with Haduvio™?

The ongoing trials are the Phase 2b CORAL and Phase 2a RIVER trials.

Where will Trevi present its research findings?

Trevi will present at the Thirteenth London International Cough Symposium.

Is there a treatment for chronic cough in IPF?

Currently, there are no approved therapies for chronic cough in IPF.

Who can be affected by refractory chronic cough?

Refractory chronic cough can affect up to 10% of the adult population.

Last updated: Jul 2, 2024