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NEW HAVEN, Conn.,Aug. 28, 2025/PRNewswire/ --Trevi Therapeutics, Inc.(Nasdaq:TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (non-IPF ILD), and refractory chronic cough (RCC), today announced that senior management will be participating in the following conferences in September.
2025 Wells Fargo Healthcare ConferenceSeptember 3– 5, 2025,Everett, MassachusettsTrevi Representatives:Jennifer Good, President and CEO, and Farrell Simon, Pharm.D. CCO
Cantor Global Healthcare Conference 2025September 3– 5, 2025,New York, New YorkTrevi Representatives:Jennifer Good, President and CEO, andJames Cassella, Ph.D., CDO
Morgan Stanley 23rdAnnual Global Healthcare ConferenceSeptember 8– 10, 2025,New York, New YorkFireside Chat:September 9,4:05 p.m. ETTrevi Representatives:Jennifer Good, President and CEO, andJames Cassella, Ph.D., CDORegister here to watch the live presentation.
H.C. Wainwright & Co. 27thAnnual Global Investment ConferenceSeptember 8– 10, 2025,New York, New YorkTrevi Representatives:Jennifer Good, President and CEO, and Farrell Simon, Pharm.D. CCO
2025 Leerink Partners Biopharma SummitSeptember 17– 19, 2025,Healdsburg, CaliforniaTrevi Representative:Jennifer Good, President and CEO
European Respiratory Society (ERS) CongressSeptember 27–October 1, 2025,Amsterdam, NetherlandsTrevi Representatives:Jennifer Good, President and CEO, andJames Cassella, Ph.D., CDO,Danine Summers, Vice President of Medical Affairs, andAbbey Nakano, Pharm.D., Associate Director of Medical Affairs
About Trevi Therapeutics, Inc.Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine extended-release) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (non-IPF ILD), and refractory chronic cough (RCC). Haduvio is the first and only investigational therapy to show a statistically-significant reduction in cough frequency in clinical trials of patients with IPF chronic cough and in patients with RCC. Haduvio acts on the cough reflex arc both centrally and peripherally as a kappa agonist and a mu antagonist (KAMA), targeting opioid receptors that play a key role in controlling chronic cough. Nalbuphine is not currently scheduled by the U.S. Drug Enforcement Agency.
Chronic cough is a highly prevalent condition, impacting up to 85% of patients with IPF. There are ~150,000 patients in the U.S. with IPF. The impact of chronic cough is significant with patients coughing up to 1,500 times per day. This consistent cough and any associated damage may lead to worsening disease, a higher risk of progression, death, or need for lung transplant. Chronic cough also often leads to a decline in patients' social, physical, and psychological quality of life. There are no approved therapies for the treatment of chronic cough in patients with IPF and current off-label treatment options provide minimal benefit to patients.
Refractory chronic cough has no approved therapies in the U.S. and is defined as a persistent cough lasting >8 weeks despite treatment for an underlying condition (i.e., asthma, gastroesophageal reflux disease, non-asthmatic eosinophilic bronchitis, and upper airway cough syndrome or post-nasal drip) and includes unexplained chronic cough. RCC affects ~2-3 million patients in the U.S. and is caused by cough reflex hypersensitivity in both the central and peripheral nerves. It is a highly debilitating disease and accompanied by a wide range of complications, ranging from urinary incontinence in females to sleep disruption and social embarrassment that causes significant social and economic burdens for patients and those around them.
Trevi intends to propose Haduvio as the trade name for oral nalbuphine ER. Its safety and efficacy have not been evaluated by any regulatory authority.
For more information, visitwww.TreviTherapeutics.comand follow Trevi onX(formerly Twitter) andLinkedIn.
Investor ContactJonathan CarlsonTrevi Therapeutics, Inc.(203) 654 3286[email protected]
Media ContactRosalia Scampoli914-815-1465[email protected]
SOURCE Trevi Therapeutics, Inc.