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Telix Highlights ProstACT GLOBAL and STARLITE-1 Therapy Studies in Prostate and Kidney Cancer at ASCO Annual Meeting 2024

Key Takeaway: Telix Pharmaceuticals will present two significant studies at the 2024 ASCO Annual Meeting. The ProstACT GLOBAL study evaluates TLX591 in metastatic castrate-resistant prostate cancer, while the STARLITE-1 trial investigates TLX250 in advanced clear cell renal cell carcinoma. Both studies aim to enhance treatment options for these aggressive cancers.

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POSITIVE FACTORS

  • Presentation of two promising studies at a major oncology conference.
  • Focus on innovative therapies for prostate and kidney cancer.
  • Collaboration opportunities highlighted at the event.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+13%
120-day peak, hindsight
Typical move
7%
average across 7 past catalysts
Lead asset
131I-IPA
Phase 1 · Neoplastic Disease

Full Press Release Details

Melbourne (Australia) | 27 May 2024
Telix today announces two abstract presentations featuring the Company’s therapeutic radiopharmaceutical programs at the upcoming 2024 American Society of Clinical Oncology (ASCO) Annual Meeting being held in Chicago, Illinois from May 31 – June 4, 2024.
Oliver Sartor MD, Professor at Mayo Clinic (Rochester, MN) will present Telix’s ProstACT GLOBAL study of TLX591 (lutetium Lu 177 rosopatamab tetraxetan), the first Phase III trial to evaluate the radio antibody-drug conjugate (rADC) approach in patients with prostate-specific membrane antigen (PSMA)-positive metastatic castrate-resistant prostate cancer (mCRPC).
Eric Jonasch, MD, Professor at MD Anderson Cancer Center (Houston, TX) will present the Phase II STARLITE-1 investigator-initiated trial of Telix’s carbonic anhydrase IX (CAIX)-targeting investigational therapy, TLX250 ( 177 Lu-DOTA-girentuximab), in combination with immunotherapy in clear cell renal cell carcinoma, the most common and aggressive form of kidney cancer.
Come and meet the team at booth #21148 to discuss Telix’s extensive theranostic pipeline, our associated medical devices and artificial intelligence (AI), and opportunities for collaboration.

ASCO presentation details are as follows (all times CDT):

Title: ProstACT GLOBAL: A Phase III study of best standard of care with and without TLX591 for patients with PSMA expressing metastatic castration-resistant prostate cancer progressing despite prior treatment with a novel androgen axis drug
Presenter: Oliver Sartor, MD, Mayo Clinic
Date and Time: Sunday, June 2 | 9:00 am – 12:00pm
Session: Genitourinary Cancer – Prostate, Testicular, and Penile
Abstract ID : TPS5115 (Poster Bd 517a)
Location: Hall A & On Demand
Title: STARLITE-1: A Phase Ib/II study of combination TLX250 plus cabozantinib and nivolumab in treatment naive patients with advanced clear cell RCC
Presenter: Eric Jonasch, MD, The University of Texas MD Anderson Cancer Center
Date and Time: Sunday, June 2 | 9:00 am – 12:00pm
Session: Genitourinary Cancer – Kidney and Bladder
Abstract ID : TPS4610 (Poster Bd 303b)
Location: Hall A & On Demand
For more information and to register, visit here .
TLX591 and TLX250 have not received marketing authorisation in any jurisdiction.

Frequently Asked Questions

What studies will Telix present at ASCO 2024?

Telix will present the ProstACT GLOBAL study and the STARLITE-1 trial.

What is TLX591 used for?

TLX591 is evaluated for treating metastatic castrate-resistant prostate cancer.

Who is presenting the studies?

Oliver Sartor, MD, and Eric Jonasch, MD, will present the studies.

Where can I find Telix at ASCO 2024?

Visit Telix at booth #21148 during the ASCO Annual Meeting.

Last updated: May 27, 2024