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Tiziana Life Sciences Announces Chief Medical Officer Invited to Give Presentation on Intranasal Foralumab on May 17

Key Takeaway: Tiziana Life Sciences announced that its Chief Medical Officer will present on intranasal foralumab at the Hanson Wade Novel Nasal Formulation and Delivery Summit. This presentation showcases the growing interest in Tiziana's innovative immunomodulation therapies, particularly the unique delivery method of the fully human anti-CD3 monoclonal antibody. The company anticipates launching Phase 2 trials for intranasal foralumab in patients with non-active secondary progressive multiple sclerosis in the upcoming quarter, marking a significant step forward for their clinical research. Tiziana's efforts reflect a commitment to alternative immunotherapy approaches and enhancing treatment efficacy.

Market Sentiment Analysis

POSITIVE FACTORS

  • The Chief Medical Officer's presentation reflects recognition and prestige within the industry.
  • Intranasal foralumab has captured attention from pharma, investors, and the media, indicating strong interest.
  • The product shows promise in treating various conditions, enhancing potential market interest.
  • Phase 2 trials for intranasal foralumab are anticipated to begin soon, suggesting progress in research.

Full Press Release Details

Tiziana Life Sciences Announces
Chief Medical Officer Invited to Give Presentation on Intranasal Foralumab on May 17
NEW YORK, May 17, 2023 -- Tiziana Life Sciences Ltd. (Nasdaq:
TLSA) ("Tiziana" or the "Company"), a biotechnology company developing breakthrough immunomodulation therapies
via novel routes of drug delivery, today announced that its Chief Medical Officer, is presenting at the Hanson Wade Novel Nasal Formulation
and Delivery Summit on May 16 in San Diego.
"I was truly honored when Hanson Wade
contacted me requesting that I speak at its Novel Nasal Formulation and Delivery Summit1,"
stated Matthew W. Davis, M.D., RPh, Chief Medical Officer of Tiziana. "I will be joined at the summit by several distinguished speakers
from the industry and the FDA.2 The continued interest we receive on our intranasal
foralumab program from pharma, investors and the media demonstrates that our novel approach to deliver the only fully human anti-CD3 monoclonal
antibody intranasally has captured the attention of the medical community."
Activated T cells play an important role
in the inflammatory process. Foralumab, the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor and dampens
inflammation by modulating T cell function, thereby suppressing effector features in multiple immune cell subsets. This effect has been
demonstrated in patients with COVID and with multiple sclerosis, as well as in healthy normal subjects. Intranasal foralumab Phase 2 trials
are expected to start in the third quarter of 2023 in patients with non-active SPMS. Immunomodulation by nasal anti-CD3 mAb represents
a novel avenue for treatment of inflammatory human diseases.3
About Tiziana Life Sciences
Tiziana Life Sciences is a clinical-stage
biopharmaceutical company developing breakthrough therapies using transformational drug delivery technologies to enable alternative routes
of immunotherapy. Tiziana's innovative nasal approach has the potential to provide an improvement
in efficacy as well as safety and tolerability compared to intravenous (IV) delivery. Tiziana's lead candidate, intranasal
foralumab, which is the only fully human anti-CD3 mAb, has demonstrated a favorable safety profile and clinical response in patients in
studies to date. Tiziana's technology for alternative routes of immunotherapy has been patented with several applications pending
and is expected to allow for broad pipeline applications.
For further inquiries:
Tiziana Life Sciences Ltd
Paul Spencer, Business Development and Investor
+44 (0) 207 495 2379
LifeSci Advisors, LLC

Frequently Asked Questions

Who is presenting on intranasal foralumab?

Matthew W. Davis, M.D., RPh, Chief Medical Officer of Tiziana Life Sciences.

When will the Phase 2 trials for foralumab begin?

The Phase 2 trials are expected to start in Q3 2023.

What condition is intranasal foralumab targeting?

It targets patients with non-active secondary progressive multiple sclerosis.

What type of antibody is foralumab?

Foralumab is the only fully human anti-CD3 monoclonal antibody.

What benefits does Tiziana's nasal delivery method offer?

It may improve efficacy, safety, and tolerability compared to IV delivery.

Last updated: May 17, 2023