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Bio-Techne Launches the Enhanced Leo™ System Delivering Advanced Multiplexing and High-Throughput Protein Analysis

Key Takeaway: Bio-Techne Corporation has launched the next-generation Leo System, enhancing protein analysis with dual-channel fluorescence detection and chemiluminescence. This system allows for increased data throughput and the ability to analyze multiple targets simultaneously. Researchers can process up to 100 capillaries in three hours, achieving high precision with minimal variability. The Leo System aims to accelerate clinical research and streamline development timelines.
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POSITIVE FACTORS

  • Enhanced Leo System introduces advanced multiplexing capabilities.
  • High-throughput capabilities with only 5-6% variability.
  • Enables simultaneous quantification of distinct targets.
  • Sets a new standard for precision and efficiency in protein analysis.

Full Press Release Details

MINNEAPOLIS,Dec. 9, 2025/PRNewswire/ -- Bio-Techne Corporation (NASDAQ:TECH), a global provider of life science tools, reagents, and diagnostic products, today announced the expanded launch and first shipment of its next-generation Leo™ System, powered by Simple Western™ Technology.
The enhanced Leo System introduces dual-channel fluorescence detection alongside chemiluminescence, expanding data throughput and efficiency, and generating greater insights from precious samples. Fluorescence adds a fourth multiplexing option to its molecular weight separation, RePlex, and resampling capabilities to create even more experimental flexibility and tackle complex biological questions. This advance enables researchers to simultaneously quantify targets with distinct expression levels, assess different proteoforms, such as phosphorylated and total protein forms, in the same capillary, multiplex same-weight targets in a single run, and process up to 100 capillaries within three hours.
"Leo represents the future of clinical research requiring absolute quantitation. We chose Leo for its high-throughput capabilities and are consistently achieving highly precise results with only 5–6% variability, which is truly remarkable," said Alexandre Lucas, Ph.D., Founder and Manager of We-Met, a research group at the French National Institute of Health and Medical Research (INSERM).
"The next-generation Leo System sets a new standard for our customers by delivering unmatched precision and efficiency in protein analysis," said Will Geist, President of the Protein Sciences Segment at Bio-Techne. "With advanced detection technologies and built-in compliance features, Leo enables researchers to achieve faster, more reliable results, accelerate critical discoveries, and streamline development timelines."
Explore Leo's enhanced functionality atbio-techne.com/leoand view its new fluorescence-based detection capabilities.

ABOUT BIO-TECHNE:

Bio-Techne Corporation (NASDAQ:TECH) is a global life sciences company providing innovative tools and bioactive reagents for research and clinical diagnostic communities. Bio-Techne products assist scientific investigations into biological processes and the nature and progress of specific diseases. They aid in drug discovery efforts and provide the means for accurate clinical tests and diagnoses. With hundreds of thousands of products in its portfolio, Bio-Techne generated over $1.2 billion in net sales in fiscal 2025 and has approximately 3,100 employees worldwide. For more information on Bio-Techne and its brands, please visithttps://www.bio-techne.comor follow the company on social media atLinkedIn,X, orYouTube.
MEDIA CONTACTS:
Corporate Communications[email protected]
David Clair, Vice PresidentInvestor Relations & Corporate Development[email protected]

Frequently Asked Questions

What is the enhanced Leo System?

The enhanced Leo System is a next-generation tool for protein analysis, featuring advanced multiplexing and high-throughput capabilities.

How does the Leo System improve protein analysis?

It introduces dual-channel fluorescence detection, allowing simultaneous quantification of multiple targets and greater experimental flexibility.

What are the throughput capabilities of the Leo System?

The Leo System can process up to 100 capillaries within three hours.

What is the variability rate achieved by the Leo System?

The system achieves a remarkable variability rate of only 5-6%.

Last updated: Dec 9, 2025