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Spyre Therapeutics Announces Grants of Inducement Awards

Key Takeaway: Spyre Therapeutics announced the grant of stock options to Kate Chevlen, appointed as the new Chief Commercial Officer. The grant includes options to purchase 108,155 shares at an exercise price of $34.09, following Nasdaq Listing Rule 5635(c)(4). The options are part of Spyre's 2018 Equity Inducement Plan and are expected to vest over time. Spyre is focused on developing long-acting antibodies for treating inflammatory bowel disease and rheumatic diseases.

Market Sentiment Analysis

POSITIVE FACTORS

  • Spyre Therapeutics is expanding its leadership team by appointing a new Chief Commercial Officer.
  • The grant of stock options serves as an inducement for the new hire, indicating confidence in the employee's potential impact.
  • Spyre is pioneering long-acting antibodies, which may significantly enhance treatment options for inflammatory bowel disease and rheumatic diseases.

Full Press Release Details

WALTHAM, Mass., Jan. 23, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease and rheumatic diseases, today announced that Spyre’s independent Compensation Committee of the Board of Directors approved the grant of stock options to purchase 108,155 shares of common stock of Spyre to an employee, Kate Chevlen, in connection with her appointment as Chief Commercial Officer, as an equity inducement award under the Spyre Therapeutics, Inc. 2018 Equity Inducement Plan, as amended (the “2018 Plan”). The stock options were approved on January 22, 2026 and were material to the employee's acceptance of employment with Spyre, in accordance with Nasdaq Listing Rule 5635(c)(4).
The stock options were granted with a 10-year term and an exercise price equal to $34.09, the closing price per share of Spyre's common stock as reported by Nasdaq on January 22, 2026. The options granted to the employee shall vest and become exercisable as to one-fourth (1/4th) of the shares subject to the respective options on the first anniversary of the employee’s start date, and one-forty-eighth (1/48th) of the shares subject to the respective options shall vest and become exercisable monthly thereafter, in each case, subject to continuous service with Spyre through the applicable vesting dates. The stock options are subject to the terms of the 2018 Plan.
About Spyre Therapeutics
Spyre Therapeutics is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases. Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, and IL-23.
For more information, please visit http://spyre.com.
SVP of Finance and Investor Relations

Frequently Asked Questions

What recent stock option grant did Spyre Therapeutics announce?

Spyre Therapeutics granted stock options to Kate Chevlen for 108,155 shares.

Who approved the stock options at Spyre Therapeutics?

The independent Compensation Committee of the Board approved the stock options.

What is the exercise price of the stock options?

The exercise price of the stock options is $34.09 per share.

How will the stock options vest for Kate Chevlen?

The options will vest one-fourth after one year and then monthly thereafter.

What diseases does Spyre Therapeutics focus on?

Spyre focuses on inflammatory bowel disease and rheumatic diseases.

Last updated: Jan 23, 2026