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Spyre Therapeutics Announces Grants of Inducement Awards - May 1, 2026

Key Takeaway: Spyre Therapeutics has granted stock options to four non-executive employees as part of its 2018 Equity Inducement Plan. The options, totaling 20,800 shares, were approved on May 1, 2026, and are crucial for employee retention and recruitment. The exercise price is set at $69.42, aligning with the company's closing stock price on the same day.
Price reaction · baseline $69.42 (2026-05-01 close) · hit pre-market · 1 other SYRE headline(s) in the window, move may be shared
day 0 close
-0.4%

Market Sentiment Analysis

POSITIVE FACTORS

  • Spyre Therapeutics is expanding its team with stock options for new employees.
  • The stock options are part of a strategic plan to attract talent.
  • The company is focused on innovative treatments for inflammatory bowel disease and rheumatic diseases.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+82%
120-day peak, hindsight
Typical move
5.6%
average across 5 past catalysts
Cash runway
~47 mo
Minimal dilution risk
Lead asset
SPY002-072
Phase 2 · Rheumatoid Arthritis

Full Press Release Details

WALTHAM, Mass., May 01, 2026(GLOBE NEWSWIRE)-- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease and rheumatic diseases, today announced that Spyre’s independent Compensation Committee of the Board of Directors approved the grant of stock options to purchase an aggregate of 20,800 shares of common stock of Spyre to four non-executive employees as equity inducement awards under the Spyre Therapeutics, Inc. 2018 Equity Inducement Plan, as amended (the “2018 Plan”). The stock options were approved on May 1, 2026 and were material to each employee's acceptance of employment with Spyre, in accordance with Nasdaq Listing Rule 5635(c)(4).
The stock options were granted with a 10-year term and an exercise price equal to $69.42, the closing price per share of Spyre's common stock as reported by Nasdaq on May 1, 2026. The options granted to the employees shall vest and become exercisable as to one-fourth (1/4th) of the shares subject to the respective options on the first anniversary of the employee’s start date, and one-forty-eighth (1/48th) of the shares subject to the respective options shall vest and become exercisable monthly thereafter, in each case, subject to continuous service with Spyre through the applicable vesting dates. The stock options are subject to the terms of the 2018 Plan.

About Spyre Therapeutics

Spyre Therapeutics is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases. Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, and IL-23.
For more information, please visit http://spyre.com.

For Investors:Eric McIntyreSVP of Finance and Investor RelationsSpyre TherapeuticsEric.mcintyre@spyre.com

Frequently Asked Questions

What are the stock options granted by Spyre Therapeutics?

Spyre Therapeutics granted stock options to purchase 20,800 shares to four non-executive employees.

What is the exercise price of the stock options?

The exercise price for the stock options is set at $69.42 per share.

What is the vesting schedule for the stock options?

The options vest one-fourth after one year and monthly thereafter, subject to continuous service.

Why were the stock options granted?

The stock options were granted as part of the 2018 Equity Inducement Plan to attract talent.

Last updated: May 4, 2026