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Spyre Therapeutics Announces Grants of Inducement Awards

Key Takeaway: Spyre Therapeutics announced the approval of stock options and RSUs for two non-executive employees. The grants, totaling 11,138 shares of common stock and 3,195 RSUs, were made under the 2018 Equity Inducement Plan. The options have a 10-year term with an exercise price of $95.51, aligning with the company's commitment to attract talent.

Market Sentiment Analysis

POSITIVE FACTORS

  • Spyre granted stock options and RSUs to attract talent.
  • The options have a favorable exercise price of $95.51.
  • The company is committed to advancing immunology therapies.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+49%
120-day peak, hindsight
Typical move
9%
average across 9 past catalysts
Cash runway
~41 mo
Low dilution risk
Lead asset
SPY002-072
Phase 2 · Rheumatoid Arthritis

Full Press Release Details

WALTHAM, Mass., Nov. 06, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company committed to developing next-generation therapies that elevate the standard in immunology by delivering more complete disease control, greater durability, and a simpler treatment experience for patients, today announced that Spyre’s independent Compensation Committee of the Board of Directors approved the grant of stock options to purchase an aggregate of 11,138 shares of common stock of Spyre and 3,195 restricted stock units (“RSUs”) to two non-executive employees as equity inducement awards under the Spyre Therapeutics, Inc. 2018 Equity Inducement Plan, as amended (the “2018 Plan”). The stock options and RSUs were approved on November 2, 2026 and were material to each employee's acceptance of employment with Spyre, in accordance with Nasdaq Listing Rule 5635(c)(4).
The stock options were granted with a 10-year term and an exercise price equal to $95.51, the closing price per share of Spyre's common stock as reported by Nasdaq on November 2, 2026. The options granted to the employees shall vest and become exercisable as to one-fourth (1/4th) of the shares subject to the respective options on the first anniversary of the employee’s start date, and one-forty-eighth (1/48th) of the shares subject to the respective options shall vest and become exercisable monthly thereafter, in each case, subject to continuous service with Spyre through the applicable vesting dates. The RSUs granted to the employees shall vest as to one-fourth (1/4th) of the shares subject to the respective RSUs on each anniversary of the next November 15 occurring on or after the employee’s start date, subject to continuous service with Spyre through the applicable vesting dates. The stock options and RSUs are subject to the terms of the 2018 Plan.

About Spyre Therapeutics

Spyre Therapeutics is a clinical-stage biotechnology company committed to developing next-generation therapies that elevate the standard in immunology by delivering more complete disease control, greater durability, and a simpler treatment experience for patients. Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, IL-23, and IL-17A/F as well as rational combination programs.
For more information, please visit http://spyre.com.

For Investors: Eric McIntyre SVP of Finance and Investor Relations Spyre Therapeutics Eric.mcintyre@spyre.com

Frequently Asked Questions

What are the inducement awards granted by Spyre?

Spyre granted stock options and RSUs to two non-executive employees.

How many shares were included in the inducement awards?

The awards included 11,138 shares of common stock and 3,195 RSUs.

What is the exercise price of the stock options?

The exercise price of the stock options is $95.51.

What is the vesting schedule for the options?

Options vest 1/4th on the first anniversary and monthly thereafter.

Last updated: Nov 6, 2026