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Spyre Therapeutics Announces Grants of Inducement Awards

Key Takeaway: Spyre Therapeutics has announced the approval of stock options and restricted stock units (RSUs) for two non-executive employees as part of its 2018 Equity Inducement Plan. The grants, totaling 21,424 stock options and 6,604 RSUs, are designed to enhance employee retention and align interests with the company's long-term goals. The options have a 10-year term and a competitive exercise price.

Market Sentiment Analysis

POSITIVE FACTORS

  • Spyre Therapeutics is expanding its team with equity inducement awards.
  • The grants are part of a strategy to attract and retain talent.
  • The stock options and RSUs are structured to incentivize long-term commitment.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+75%
120-day peak, hindsight
Typical move
5.6%
average across 5 past catalysts
Cash runway
~47 mo
Minimal dilution risk
Lead asset
SPY002-072
Phase 2 · Rheumatoid Arthritis

Full Press Release Details

WALTHAM, Mass., Oct. 02, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company committed to developing next-generation therapies that elevate the standard in immunology by delivering more complete disease control, greater durability, and a simpler treatment experience for patients, today announced that Spyre’s independent Compensation Committee of the Board of Directors approved the grant of stock options to purchase an aggregate of 21,424 shares of common stock of Spyre and 6,604 restricted stock units (“RSUs”) to two non-executive employees as equity inducement awards under the Spyre Therapeutics, Inc. 2018 Equity Inducement Plan, as amended (the “2018 Plan”). The stock options and RSUs were approved on October 1, 2026 and were material to each employee's acceptance of employment with Spyre, in accordance with Nasdaq Listing Rule 5635(c)(4).
The stock options were granted with a 10-year term and an exercise price equal to $89.93, the closing price per share of Spyre's common stock as reported by Nasdaq on October 1, 2026. The options granted to the employees shall vest and become exercisable as to one-fourth (1/4th) of the shares subject to the respective options on the first anniversary of the employee’s start date, and one-forty-eighth (1/48th) of the shares subject to the respective options shall vest and become exercisable monthly thereafter, in each case, subject to continuous service with Spyre through the applicable vesting dates. The RSUs granted to the employees shall vest as to one-fourth (1/4 th) of the shares subject to the respective RSUs on each anniversary of the next February 15, May 15, August 15, or November 15 occurring on or after the employee’s start date, subject to continuous service with Spyre through the applicable vesting dates. The stock options and RSUs are subject to the terms of the 2018 Plan.

About Spyre Therapeutics

Spyre Therapeutics is a clinical-stage biotechnology company committed to developing next-generation therapies that elevate the standard in immunology by delivering more complete disease control, greater durability, and a simpler treatment experience for patients. Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, IL-23, and IL-17A/F as well as rational combination programs.
For more information, please visit http://spyre.com.

For Investors: Eric McIntyre SVP of Finance and Investor Relations Spyre Therapeutics Eric.mcintyre@spyre.com

Frequently Asked Questions

What are the inducement awards granted by Spyre Therapeutics?

Spyre Therapeutics granted stock options and restricted stock units (RSUs) to two non-executive employees.

How many shares were included in the inducement awards?

The inducement awards included 21,424 stock options and 6,604 RSUs.

What is the exercise price for the stock options?

The exercise price for the stock options is $89.93.

What is the vesting schedule for the stock options?

The stock options vest one-fourth on the first anniversary and monthly thereafter.

Last updated: Oct 2, 2026