Recent Updates
Recently added Catalysts
STTK Positive Sentiment

Shattuck Labs to Host Investor Call and Webcast on Phase 1 Clinical Data of SL-325, a Potentially First-in-Class DR3 Blocking Antibody, and Pipeline Update on June 8

Key Takeaway: Shattuck Labs will host an investor call on June 8, 2026, to discuss Phase 1 clinical data for SL-325, a DR3 blocking antibody. The presentation will cover safety, pharmacokinetics, and immunogenicity results, along with a pipeline update. Key executives will present and participate in a Q&A session.
Price reaction · baseline $4.8 (2026-06-04 close) · hit after-hours · 4 other STTK headline(s) in the window, move may be shared
day 0 close · peak
-4.6%

Market Sentiment Analysis

POSITIVE FACTORS

  • Shattuck Labs presents promising Phase 1 data for SL-325.
  • The drug targets a validated pathway with a favorable safety profile.
  • The investor call will provide comprehensive insights into the pipeline.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+161%
120-day peak, hindsight
Typical move
7.5%
average across 5 past catalysts
Cash runway
~65 mo
Minimal dilution risk
Lead asset
SL-325
Phase 2 · Crohn's Disease

Full Press Release Details

AUSTIN, Texas and DURHAM, N.C., June 05, 2026 (GLOBE NEWSWIRE) -- Shattuck Labs, Inc. (Shattuck) (NASDAQ: STTK), a clinical-stage biotechnology company pioneering the development of potentially first-in-class monoclonal and bispecific DR3-blocking antibodies for the treatment of patients with inflammatory and immune-mediated diseases, today announced that it will host an investor call and webcast on Monday, June 8, 2026 at 8:00 a.m. ET to present comprehensive Phase 1 clinical data for SL-325, including safety, tolerability, pharmacokinetics, receptor occupancy, pharmacodynamic and immunogenicity results and provide a pipeline update.
The event will feature presentations by members of Shattuck’s management team, including Taylor Schreiber, M.D., Ph.D., Chief Executive Officer, Lini Pandite, M.D., M.B.A., Chief Medical Officer, Suresh De Silva, Ph.D., Chief Scientific Officer, Michael Choi, M.D., Vice President of Clinical Development, and Andrew Neill, M.B.A., Chief Financial Officer, followed by a question-and-answer session.

Conference Details

Title: Phase 1 Clinical Data of SL-325, a Potentially First-in-Class DR3 Blocking Antibody, and Pipeline UpdateDate & Time:Monday, June 8, 2026 at 8:00 a.m. ETWebcast Details:Click here
Interested parties can access the live webcast via the Events & Presentations section of the Company’s website atwww.shattucklabs.com. A replay of the webcast will be available for approximately 30 days following the event.
About SL-325SL-325 is a potential first-in-class Death Receptor 3 (DR3) blocking antibody designed to achieve a complete and durable blockade of the clinically validated DR3/TL1A pathway. Shattuck’s preclinical studies demonstrate high affinity binding and superior activity over TL1A antibodies, and offer a data-driven rationale for targeting the TNF receptor, DR3, versus its ligand, TL1A. SL-325 is a fully Fc-silenced, fully human immunoglobulin G monoclonal antibody with a favorable safety profile in non-human primates, currently being evaluated in a Phase 1 clinical trial.
About Shattuck Labs, Inc.Shattuck Labs, Inc. is a clinical-stage biotechnology company pioneering the development of potentially first-in-class monoclonal and bispecific DR3 blocking antibodies for the treatment of patients with inflammatory and immune-mediated diseases. Shattuck’s expertise in protein engineering and the development of novel TNF receptor therapeutics come together in its lead program, SL-325, a potentially first-in-class DR3 antagonist antibody designed to achieve a more complete blockade of the clinically validated DR3/TL1A pathway. The Company has offices in both Austin, Texas and Durham, North Carolina. For more information, please visit: www.ShattuckLabs.com.

Investor & Media Contact:Andrew R. NeillChief Financial OfficerShattuck Labs, Inc.InvestorRelations@shattucklabs.com

Frequently Asked Questions

What is SL-325?

SL-325 is a potentially first-in-class DR3 blocking antibody targeting inflammatory diseases.

When will the investor call take place?

The investor call is scheduled for June 8, 2026, at 8:00 a.m. ET.

What will be discussed during the call?

The call will cover Phase 1 clinical data, including safety and pharmacokinetics.

How can I access the webcast?

The webcast can be accessed via the Events & Presentations section of Shattuck's website.

Last updated: Jun 5, 2026