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Shattuck Labs to Participate in Upcoming December Investor Conferences

Key Takeaway: Shattuck Labs, Inc. announced its participation in several investor conferences in December 2025, including the Piper Sandler 37th Annual Healthcare Conference and the Evercore ISI 8th Annual HealthCONx Conference. CEO Taylor Schreiber will present at both events, discussing the company's innovative therapies targeting TNF superfamily receptors. The company is advancing its lead program, SL-325, currently in Phase 1 trials.
Price reaction · baseline $1.96 (2025-11-19 close) · hit pre-market · clean, no other STTK news in the window
day 0 close · peak
-1.5%

Market Sentiment Analysis

POSITIVE FACTORS

  • Participation in multiple investor conferences highlights company visibility.
  • CEO Taylor Schreiber will present at notable healthcare events.
  • Potential first-in-class therapeutic SL-325 shows promising preclinical results.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+161%
120-day peak, hindsight
Typical move
7.5%
average across 5 past catalysts
Cash runway
~65 mo
Minimal dilution risk
Lead asset
SL-325
Phase 2 · Crohn's Disease

Full Press Release Details

AUSTIN, TX and DURHAM, NC, Nov. 20, 2025 (GLOBE NEWSWIRE) -- Shattuck Labs, Inc. (“Shattuck” or the “Company”) (NASDAQ: STTK), a clinical-stage biotechnology company pioneering the development of novel therapeutics targeting tumor necrosis factor (TNF) superfamily receptors for the treatment of patients with inflammatory and immune-mediated diseases, today announced that Company management will participate in multiple investor conferences in December 2025.

Conference Details

Conference:Piper Sandler 37thAnnual Healthcare ConferenceFormat:Presentation and one-on-one meetingsPresenter:Taylor Schreiber, M.D., Ph.D., Chief Executive OfficerPresentation Date:Dec 2, 2025Time:10:10 AM ESTLocation:New York, NYWebcast link:HERE
Conference:Evercore ISI 8thAnnual HealthCONx ConferenceFormat:Fireside chat with Umer Raffat and Jonathan Miller, Ph.D. and one-on-one meetings (Dec 3-4)Presenter:Taylor Schreiber, M.D., Ph.D., Chief Executive OfficerFireside Chat Date:Dec 4, 2025Time:8:20 AM ESTLocation:Coral Gables, FLWebcast link:HERE
A replay of the presentations from the Piper Sandler 37thAnnual Healthcare Conference and the Evercore ISI 8thAnnual HealthCONx Conference will be available on theEvents and Presentationssection of the Company’s website. A replay of the webcasts will remain archived for up to 30 days following the presentation date.

About SL-325

SL-325 is a potential first-in-class Death Receptor 3 (DR3) blocking antibody designed to achieve a complete and durable blockade of the clinically validated DR3/TL1A pathway. Shattuck’s preclinical studies demonstrate high affinity binding and superior activity over TL1A antibodies and offer a data-driven rationale for targeting the TNF receptor, DR3, versus its ligand, TL1A. SL-325 is a fully Fc-silenced humanized immunoglobin G monoclonal antibody with a favorable safety profile in non-human primates, currently being evaluated in a Phase 1 clinical trial.
About Shattuck Labs, Inc.Shattuck Labs, Inc. (Nasdaq: STTK) is a clinical-stage biotechnology company specializing in the development of potential treatments for inflammatory and immune-mediated diseases. The Company is developing a potentially first-in-class antibody for the treatment of inflammatory bowel disease (IBD) and other inflammatory and immune-mediated diseases. Shattuck’s expertise in protein engineering and the development of novel TNF receptor therapeutics come together in its lead program, SL-325, a potentially first-in-class DR3 antagonist antibody designed to achieve a more complete blockade of the clinically validated DR3/TL1A pathway. The Company has offices in both Austin, Texas and Durham, North Carolina. For more information, please visit: www.ShattuckLabs.com.

Investor & Media Contact:Andrew R. NeillChief Financial OfficerShattuck Labs, Inc.InvestorRelations@shattucklabs.com

Frequently Asked Questions

What conferences will Shattuck Labs attend in December 2025?

Shattuck Labs will participate in the Piper Sandler 37th Annual Healthcare Conference and the Evercore ISI 8th Annual HealthCONx Conference.

Who will present at the investor conferences?

CEO Taylor Schreiber, M.D., Ph.D., will present at both conferences.

What is SL-325?

SL-325 is a potential first-in-class antibody targeting the DR3/TL1A pathway, currently in Phase 1 trials.

Where can I find the conference presentations?

Replays of the presentations will be available on Shattuck Labs' website for up to 30 days.

Last updated: Nov 20, 2025