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THERAPIX BIOSCIENCES LTD. Therapix Biosciences Reports Second Quarter 2018 Financial Results and Provides Business Update

Key Takeaway: THERAPIX BIOSCIENCES LTD. Therapix Biosciences Reports Second Quarter 2018 Financial Results and Provides Business Update AVIV, Israel, August 20, 2018 /PRNewswire/ -- Therapix Biosciences Ltd. (Nasdaq: TRPX) a specialty, clinical-stage pharmaceutical company focusing on the

Full Press Release Details

THERAPIX BIOSCIENCES LTD.
Therapix Biosciences Reports Second Quarter
2018 Financial Results and
Provides Business Update
AVIV, Israel, August 20, 2018 /PRNewswire/ -- Therapix Biosciences Ltd. (Nasdaq: TRPX) a specialty, clinical-stage pharmaceutical
company focusing on the development of cannabinoid-based treatments, issued today its financial summary - second
quarter 2018 vs. second quarter 2017 (Note: The functional currency of the Company is New Israeli Shekel; for presentation purposes,
the financial data herein is presented in USD):
Business update and developments
in the Company's clinical R&D programs:
Tourette Syndrome (TS):
Obstructive Sleep Apnea (OSA):
Mild Cognitive Impairment (MCI):
THX-150 is a pharmaceutical composition
of dronabinol (synthetic 9-tetrahydracannabinol) with or without palmitoylethanolamide (PEA) along with a selected antibacterial
agent that may possess synergy potential. Our objective is to use our entourage technology in association with THC to potentially
increase the efficacy of existing antibiotic drugs especially in antibiotic-resistant bacteria strains. In addition, we have initiated
a study in an animal model of a microbial infection to test the potential efficacy and safety of THX-150 in accordance with the
plan schedule during the second half of 2018.
STATEMENTS OF FINANCIAL POSITION
(Mainly based on an effective
exchange rate of 3.65 NIS/USD as of June 30, 2018)
June 30, December 31,
2018 2017 2017
Unaudited Audited
USD in thousands
ASSETS
CURRENT ASSETS:
Cash 5,103 11,784 9,195
Restricted cash 23 13 24
Accounts receivable 448 242 278
Convertible loan 705 - -
6,279 12,039 9,497
NON-CURRENT ASSETS:
Prepaid public offering costs 53 - 19
Property and equipment 53 17 50
106 17 69
6,385 12,056 9,566
LIABILITIES AND EQUITY (DEFICIT)
CURRENT LIABILITIES:
Trade payables 1,077 543 1,017
Other accounts payable 155 128 160
1,232 671 1,177
EQUITY ATTRIBUTABLE TO EQUITY HOLDERS OF THE COMPANY:
Share capital 3,812 3,812 3,812
Share premium 36,989 36,612 36,612
Reserve from share-based payment transactions 5,310 4,584 5,311
Foreign currency translation reserve 432 760 782
Transactions with non-controlling interests 261 261 261
Accumulated deficit (41,651 ) (34,644 ) (38,389 )
Total equity 5,153 11,385 8,389
6,385 12,056 9,566
STATEMENTS OF PROFIT OR LOSS
(Based on the average exchange rate of
3.56 NIS/USD for the six-month period ended June 30, 2018)
Six months ended June 30, Three months ended June 30, Year ended December 31,
2018 2017 2018 2017 2017
Unaudited Audited
USD in thousands
Research and development expenses, net 1,645 695 650 455 1,943
General and administrative expenses 2,139 1,376 1,000 971 3,810
3,784 2,071 1,650 1,426 5,753
Other expenses - - - - 1
Operating loss 3,784 2,071 1,650 1,426 5,754
Finance income (525 ) - (437 ) - (1 )
Finance expenses 3 428 1 437 491
Loss 3,262 2,499 1,214 1,863 6,244
Attributable to:
Equity holders of the Company 3,262 2,499 1,214 1,863 6,244
Non-controlling interests - - - - -
3,262 2,499 1,214 1,863 6,244
Basic and diluted loss per share attributable to equity holders of the Company 0.02 0.03 0.01 0.03 0.05
Basic and diluted loss per ADS attributable to equity holders of the Company 0.93 1.07 0.35 1.10 2.14
STATEMENTS OF COMPREHENSIVE INCOME
(Based on the average exchange rate of
3.56 NIS/USD for the six-month period ended June 30, 2018)
Six months ended June 30, Three months ended June 30, Year ended December 31,
2018 2017 2018 2017 2017
Unaudited Audited
USD in thousands
Net loss 3,262 2,499 1,214 1,863 6,244
Amounts that will not be reclassified subsequently to profit or loss:
Adjustments arising from translation financial statements from functional currency to presentation currency 350 (439 ) 266 (124 ) (461 )
Total other comprehensive income (loss) 350 (439 ) 266 (124 ) (461 )
Total comprehensive loss 3,612 2,060 1,480 1,739 5,783
Attributable to:
Equity holders of the Company 3,612 2,060 1,480 1,739 5,783
Non-controlling interests - - - - -
3,612 2,060 1,480 1,739 5,783
STATEMENTS OF CHANGES IN EQUITY
(Mainly based on the average exchange rate
of 3.56 NIS/USD for the six-month period ended June 30, 2018)
Attributable to equity holders of the Company
Share capital Share premium Reserve from share-based payment transactions Foreign currency translation reserve Transactions with non-controlling interests Accumulated deficit Total
Unaudited
USD in thousands
Balance at January 1, 2018 3,812 36,612 5,311 782 261 (38,389 ) 8,389
Loss - - - - - (3,262 ) (3,262 )
Other comprehensive loss - - - (350 ) - - (350 )
Total comprehensive loss - - - (350 ) - (3,262 ) (3,612 )
Share-Based payment - - 376 - - - 376
Expiration of share options - 377 (377 ) - - - -
Balance at June 30, 2018 3,812 36,989 5,310 432 261 (41,651 ) 5,153
STATEMENTS OF CHANGES IN EQUITY
(Mainly based on the average exchange rate
of 3.56 NIS/USD for the six-month period ended June 30, 2018)
Attributable to equity holders of the Company
Share capital Share premium Reserve from share-based payment transactions Foreign currency translation reserve Transactions with non-controlling interests Accumulated deficit Total
Unaudited
USD in thousands
Balance at January 1, 2017 1,087 26,600 4,449 321 261 (32,145 ) 573
Loss - - - - - (2,499 ) (2,499 )
Other comprehensive income - - - 439 - - 439
Total comprehensive income (loss) - - - 439 - (2,499 ) (2,060 )
Share-Based payment - - 135 - - - 135
Issuance of shares (1) 189 769 - - - - 958
Issuance of shares (2) 2,207 7,928 - - - - 10,135
Issuance of shares (3) 329 1,315 - - - - 1,644
Balance at June 30, 2017 3,812 36,612 4,584 760 261 (34,644 ) 11,385
(1) Net issuance expenses of $61,000
(2) Net issuance expenses of $1,865,000
(3) Net issuance expenses of $156,000
STATEMENTS OF CHANGES IN EQUITY
(Mainly based on the average exchange rate
of 3.56 NIS/USD for the six-month period ended June 30, 2018)
Attributable to equity holders of the Company
Share capital Share premium Reserve from share-based payment transactions Foreign currency translation reserve Transactions with non-controlling interests Accumulated deficit Total
Unaudited
USD in thousands
Balance at March 31, 2018 3,812 36,829 5,332 698 261 (40,437 ) 6,495
Loss - - - - - (1,214 ) (1,214 )
Other comprehensive loss - - - (266 ) - - (266 )
Total comprehensive loss - - - (266 ) - (1,214 ) (1,480 )
Share-based payment - - 138 - - - 138
Expiration of share options - 160 (160 ) - - - -
Balance at June 30, 2018 3,812 36,989 5,310 432 261 (41,651 ) 5,153
STATEMENTS OF CHANGES IN EQUITY
(Mainly based on the average exchange rate
of 3.56 NIS/USD for the six-month period ended June 30, 2018)
Attributable to equity holders of the Company
Share capital Share premium Reserve from share-based payment transactions Foreign currency translation reserve Transactions with non-controlling interests Accumulated deficit Total
Unaudited
USD in thousands
Balance at March 31, 2017 3,483 35,297 4,513 636 261 (32,781 ) 11,409
Loss - - - - - (1,863 ) (1,863 )
Other comprehensive income - - - 124 - - 124
Total comprehensive income (loss) - - - 124 - (1,863 ) (1,739 )
Share-based payment - - 71 - - - 71
Issuance of shares (1) 329 1,315 - - - - 1,644
Balance at June 30, 2017 3,812 36,612 4,584 760 261 (34,644 ) 11,385
(1) Net issuance expenses of $156,000
STATEMENTS OF CHANGES IN EQUITY
(Mainly based on the average exchange rate
of 3.56 NIS/USD for the six-month period ended June 30, 2018)
Attributable to equity holders of the Company
Share capital Share premium Reserve from share-based payment transactions Foreign currency translation reserve Transactions with non-controlling interests Accumulated deficit Total
Audited
USD in thousands
Balance at January 1, 2017 1,087 26,600 4,449 321 261 (32,145 ) 573
Loss - - - - - (6,244 ) (6,244 )
Other comprehensive income - - - 461 - - 461
Total comprehensive income (loss) - - - 461 - (6,244 ) (5,783 )
Share-Based payment - - 862 - - - 862
Issuance of shares (1) 189 769 - - - - 958
Issuance of shares (2) 2,207 7,928 - - - - 10,135
Issuance of shares (3) 329 1,315 - - - - 1,644
Balance at December 31, 2017 3,812 36,612 5,311 782 261 (38,389 ) 8,389
(1) Net issuance expenses of $61,000
(2) Net issuance expenses of $1,865,000
(3) Net issuance expenses of $156,000
STATEMENTS OF CASH FLOWS
(Based on the average exchange rate of
3.56 NIS/USD for the six-month period ended June 30, 2018)
Six months ended June 30, Three months ended June 30, Year ended December 31,
2018 2017 2018 2017 2017
Unaudited Audited
USD in thousands
Cash flows from operating activities:
Net loss (3,262 ) (2,499 ) (1,214 ) (1,863 ) (6,244 )
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization 6 2 3 1 5
Gain from sale of equipment - - - - 1
Share-based payment expense 376 135 138 71 862
Finance expenses (incomes), net (512 ) 446 (422 ) 453 525
(130 ) 583 (281 ) 525 1,393
Working capital adjustments:
Increase in accounts receivable (189 ) (110 ) (50 ) (102 ) (143 )
Decrease (increase) in trade payables 113 (101 ) (101 ) (406 ) 349
Decrease (increase) in other accounts payable 3 33 (189 ) (54 ) 66
(73 ) (178 ) (340 ) (562 ) 272
Net cash used in operating activities (3,465 ) (2,094 ) (1,835 ) (1,900 ) (4,579 )
Cash flows from investing activities:
Increase in restricted cash - (2 ) - (2 ) (11 )
Proceed from sale of equipment - - - - 2
Purchase of equipment (12 ) (7 ) (3 ) (7 ) (44 )
Grant of convertible loan (500 ) - (500 ) - -
Net cash used in investing activities (512 ) (9 ) (503 ) (9 ) (53 )
Cash flows from financing activities:
Prepaid public offering costs (36 ) - 1 - (18 )
Proceeds from issuance of share capital (net of issuance expenses) - 13,167 - 1,943 13,193
Net cash provided by (used in) financing activities (36 ) 13,167 1 1,943 13,175
Exchange rate differences on cash and cash equivalents in foreign currency 308 (446 ) 218 (453 ) (527 )
Translation differences on cash and cash equivalents (387 ) 490 (287 ) 149 503
Increase (decrease) in cash (4,092 ) 11,108 (2,406 ) (270 ) 8,519
Cash at the beginning of the period 9,195 676 7,509 12,054 676
Cash at the end of the period 5,103 11,784 5,103 11,784 9,195
(Based on the average exchange rate of
3.56 NIS/USD for the six-month period ended June 30, 2018)
Six months ended June 30, Three months ended June 30, Year ended December 31,
2018 2017 2018 2017 2017
Unaudited Audited
USD in thousands
Research and Development Expenses:
Clinical studies 372 256 118 163 511
R&D and preclinical studies 423 158 268 119 362
Wages and related expenses 335 140 127 57 321
Share-based payment 80 24 33 11 103
Regulatory and other expenses 384 117 104 105 276
Chemistry and formulation studies 51 - - - 330
1,645 695 650 455 1,943
General and Administrative Expenses:
Investor relations and business expenses 164 388 55 340 871
Professional and director fees 713 394 259 302 1,007
Regulatory expenses 35 53 20 29 80
Business development 484 - 393 - 74
Wages and related expenses 347 343 120 185 808
Office, maintenance, rent and other expenses 100 87 48 55 211
Share-based payment 296 111 105 60 759
2,139 1,376 1,000 971 3,810
On July 31, 2018, the Company entered into
an Agreement for Convertible Equity (the "Convertible Equity Agreement") with Therapix Healthcare Resources, Inc. ("THR"),
which is a company incorporated in Delaware and an unaffiliated third party. Under the Convertible Equity Agreement, the Company
loaned an aggregate of $1,300,000 (the "Loan") to THR. The maturity date of the Loan, which accrues interest at a rate
of nine percent (9%) per annum, will be upon demand of the Company at any time after August 1, 2018, the closing date (the "Maturity
Date"). At the election of the Company, the entire Loan shall be converted into that number of shares of the most senior
class of shares of THR existing at the time of such conversion, at a price per share equal to the fair market value of such shares
as shall be determined by THR's Board of Directors, it being acknowledged that, following the exercise of such conversion
right, the Company shall hold 20.96% of THR. In addition, the Company shall have the right to appoint 50% of the members of the
THR Board of Directors. The proceeds of the Loan were used by THR to acquire eight pain clinics, seven of which are located in
Tennessee and one in Arkansas, as well as a fully equipped laboratory in Tennessee from Anesthesia Services Associates PLLC. (d/b/a
Comprehensive Pain Specialist) on August 1, 2018.
About Therapix Biosciences Ltd.:
Therapix Biosciences Ltd. is a specialty
clinical-stage pharmaceutical company led by an experienced team of Senior Executives and Scientists. Our focus is creating and
enhancing a portfolio of technologies and assets based on cannabinoid pharmaceuticals. With this focus, the company is currently
engaged in the following drug development programs based on repurposing an FDA-approved cannabinoid (Dronabinol): THX-110 for the
treatment of Tourette syndrome (TS), for the treatment of Obstructive Sleep Apnea (OSA), and the treatment of pain; THX-130 for
the treatment of Mild Cognitive Impairment (MCI) and Traumatic Brain Injury (TBI); THX-150 for the treatment of infectious diseases;
and THX-160 for the treatment of pain. Please visit our website for more information at www.therapixbio.com.
About TXH-110 (Previously referred to
as THX-TS01 and THX-OSA01):
THX-110 is a combination drug candidate
for the treatment of Tourette syndrome, Obstructive Sleep Apnea and pain. It is composed of two components: (1) dronabinol (an
FDA approved analog of 9-tetrahydracannabinol, or "THC"), and (2) palmitoylethanolamide ("PEA"), which
is an endogenous fatty acid amide that belongs to the class of nuclear factor agonists, which are molecules that regulate the expression
of genes. The combination of THC and PEA may induce a reaction known as the "Entourage Effect". The basic tenet of the
entourage effect is that cannabinoids work together, or possess synergy, and affect the body in a mechanism similar to the body's
own endocannabinoid system, which is a group of molecules and receptors in the brain that mediates the psychoactive effects of
cannabis. This entourage effect may account for the pharmacological actions of PEA. Based on an activity enhancement of other physiological
compounds, PEA may indirectly stimulate the cannabinoid receptors by potentiating their affinity for a receptor or by inhibiting
their metabolic degradation, and by doing so, may increase the uptake of cannabinoid compounds, such as THC. Thus, it is speculated
that the presence of the PEA molecule could increase the efficacy of THC, while reducing the required dosage and decreasing associated
deleterious adverse events.
THX-130 is a proprietary, innovative, formulation
of ultra-low dose dronabinol, which is intended to provide a treatment for Mild Cognitive Impairment (MCI). Recent pre-clinical
animal studies have found that an ultra-low dose of THC could potentially protect the brain from long-term cognitive impairment,
which may be caused by aging, lack of oxygen supply, seizures or use of drugs. Certain pre-clinical studies also suggest that ultra-low
doses of THC cause animals to improve performance in behavioral tests that measure learning and memory.
Last updated: Aug 20, 2018