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Silexion Therapeutics to Present SIL-204 Data in KRAS-Driven Pancreatic Cancer at the 2025 ASCO Gastrointestinal Cancers Symposium

Key Takeaway: Silexion Therapeutics Corp. will present data on SIL-204, an RNA interference therapy targeting KRAS mutations, at the 2025 ASCO Gastrointestinal Cancers Symposium. The symposium, held in San Francisco from January 23-25, aims to showcase advancements in gastrointestinal cancers. Silexion's abstract will be available prior to the presentation on January 21, and the company's innovative approaches focus on improving outcomes in challenging cancer types.

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POSITIVE FACTORS

  • Presentation of SIL-204 data at a prestigious symposium shows Silexion's active engagement in oncology research.
  • SIL-204 demonstrates significant potential against KRAS-driven cancers based on preclinical studies.
  • Silexion has promising results from its first-generation product, LODER™, in pancreatic cancer.

Full Press Release Details

Cayman Islands, January 13, 2025 -- Silexion Therapeutics Corp. (NASDAQ: SLXN) (“Silexion” or the “Company”), a clinical-stage biotech developing RNA interference (RNAi) therapies for KRAS-driven cancers, today announced that it will be presenting a poster at the 2025 ASCO Gastrointestinal (GI) Cancers Symposium taking place January 23-25, 2025, in San Francisco, California.
The 2025 ASCO Gastrointestinal Cancers Symposium is a specialized meeting designed to highlight the latest science in GI cancers and other information oncologists of all subspecialties need to know now, in order to provide the highest quality of care to patients.
Silexion’s abstract will be published on the ASCO Gastrointestinal Cancers Symposium website at 5:00 p.m. ET on January 21, 2025. Following the presentation, the poster will be available on Silexion Therapeutics’ website under the “Our Science” section.
Presentation Details
Title: SIL-204 siRNA free and encapsulated in extended release microparticles for the treatment of localized and systemic cancer that harbors a KRAS G12x, Q61H, or G13D mutation
Presenter: Mitchell Shirvan, Ph.D.
Session: Cancers of the Pancreas, Small Bowel, and Hepatobiliary Tract
Abstract Number: 745
Session Date & Time: January 24, 2025, 11:30 AM-1:00 PM PST
About Silexion Therapeutics
Silexion Therapeutics (NASDAQ: SLXN) is a pioneering clinical-stage, oncology-focused biotechnology company developing innovative RNA interference (RNAi) therapies to treat solid tumors driven by KRAS mutations, the most common oncogenic driver in human cancers. The company's first-generation product, LODER™, has shown promising results in a Phase 2 trial for non-resectable pancreatic cancer. Silexion is also advancing its next-generation siRNA candidate, SIL-204, designed to target a broader range of KRAS mutations and showing significant potential in preclinical studies. The company remains committed to pushing the boundaries of therapeutic innovation in oncology, with a focus on improving outcomes for patients with difficult-to-treat cancers. For more information please visit: https://silexion.com
Silexion Therapeutics Corp
Ms. Mirit Horenshtein Hadar, CFO
Capital Markets & IR Contact
ARX | Capital Markets Advisors
North American Equities Desk

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Frequently Asked Questions

What is Silexion Therapeutics focused on?

Silexion Therapeutics develops RNA interference therapies for KRAS-driven cancers.

Where will Silexion present its poster?

The poster will be presented at the 2025 ASCO GI Cancers Symposium in San Francisco.

What is the title of Silexion's presentation?

The presentation is titled 'SIL-204 siRNA for localized and systemic cancer treatment.'

When will Silexion's abstract be published?

The abstract will be published on January 21, 2025, at 5:00 PM ET.

Who will present the poster at the symposium?

Dr. Mitchell Shirvan will present the poster during the session.

Last updated: Jan 13, 2025