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Silo Pharma Granted U.S. Patent for Novel Intranasal Post-Traumatic Stress Disorder Treatment

Key Takeaway: Silo Pharma, Inc. announced that the U.S. Patent Office granted a patent for its innovative intranasal treatment targeting post-traumatic stress disorder (PTSD), strengthening protection for its lead asset, SPC-15. The new patent includes expanded claims on previous patents and supports ongoing collaborative research with Columbia University. SPC-15 has shown promise as an intranasal serotonin 5-HT4 receptor agonist, and its potential eligibility for a streamlined FDA approval pathway could accelerate its clinical development. Silo continues to focus on addressing underserved conditions, enhancing its biopharmaceutical pipeline.

Market Sentiment Analysis

POSITIVE FACTORS

  • U.S. Patent Office granted a patent for Silo's PTSD treatment.
  • Patent strengthens protection for lead asset SPC-15.
  • Potential for expedited FDA approval via streamlined 505(b)(2) pathway.
  • Collaboration with Columbia University enhances research capabilities.

Full Press Release Details

SARASOTA, FL, Feb. 26, 2025 (GLOBE NEWSWIRE) -- Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced that the U.S. Patent and Trademark Office (USPTO) issued an Issue Notification for our previously filed patent application (No. 17/954,864) titled “Pharmacological Prophylactics Against Stress-Induced Affective Disorders in Females.”  The projected patent number is 12,239,614 and the issue date of such patent will be March 4, 2025.
The patent reinforces protection for Silo’s lead asset, SPC-15, an intranasal treatment targeting post-traumatic stress disorder (PTSD). The patent includes newly added claims to U.S. Patent 11,491,120, which was issued to Silo in November 2022.
“Strategic IP and patent expansion is key to advancing our lead asset SPC-15 to clinical trials and creating value for our full pipeline of novel assets,” said Eric Weisblum, CEO of Silo. “This new patent further supports our collaborative research with Columbia University and expands coverage for SPC-15.”
Silo announced the USPTO’s Notice of Allowance for the new patent in January 2025.
SPC-15 is an intranasal serotonin 5-HT4 receptor agonist aimed at treating stress-induced psychiatric disorders such as PTSD and anxiety. With its potential eligibility for the FDA’s streamlined 505(b)(2) regulatory pathway, SPC-15 offers a promising approach to accelerate the approval process. Silo Pharma is collaborating with Columbia University to conduct preclinical studies and has exclusive global rights to the development and commercialization of SPC-15.
Silo Pharma Inc. (Nasdaq: SILO) is a developmental stage biopharmaceutical company focused on addressing underserved conditions, including stress-induced psychiatric disorders, chronic pain, and central nervous system (CNS) diseases. The Company’s portfolio includes innovative programs such as SPC-15 for PTSD, SP-26 for fibromyalgia and chronic pain, and preclinical assets targeting Alzheimer’s disease and multiple sclerosis. Silo’s research is conducted in collaboration with leading universities and laboratories. silopharma.com
Forward-Looking Statements
This news release contains "forward-looking statements" within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. These statements are identified using words “could”, “believe”, “anticipate”, “intend”, “estimate”, “expect”, “may”, “continue”, “predict”, “potential”, and similar expressions that are intended to identify forward-looking statements. Such statements involve known and unknown risks, uncertainties, and other factors that could cause the actual results of Silo Pharma, Inc. (“Silo” or “the Company”) to differ materially from the results expressed or implied by such statements, including changes to anticipated sources of revenues, future economic and competitive conditions, difficulties in developing the Company’s technology platforms, retaining and expanding the Company’s customer base, fluctuations in consumer spending on the Company’s products and other factors. Accordingly, although the Company believes that the expectations reflected in such forward-looking statements are reasonable, there can be no assurance that such expectations will prove to be correct. The Company disclaims any obligations to publicly update or release any revisions to the forward-looking information contained in this press release, whether as a result of new information, future events, or otherwise, after the date of this press release or to reflect the occurrence of unanticipated events except as required by law.

Frequently Asked Questions

What is SPC-15 developed by Silo Pharma?

SPC-15 is an intranasal treatment focused on PTSD and stress-induced disorders.

When will the new patent for Silo be issued?

The new patent will be issued on March 4, 2025.

What does the new patent cover?

It covers pharmacological prophylactics against stress-induced affective disorders.

Who is collaborating with Silo Pharma on SPC-15?

Silo Pharma is collaborating with Columbia University for preclinical studies.

What pathways might SPC-15 qualify for?

SPC-15 may qualify for the FDA’s streamlined 505(b)(2) regulatory pathway.

Last updated: Feb 26, 2025