SCIENTURE Secures Multiple Commercial GPO Agreements, Expanding U.S. Market Access for Arbli™ (losartan potassium) to more than 2500 Healthcare Institutions

U.S. losartan market totals $256M annually with 71M prescriptions, creating a significant opportunity for Arbli™as the first FDA-approved ready-to-use oral suspension

COMMACK, NY, Oct. 01, 2025 (GLOBE NEWSWIRE) -- SCIENTURE HOLDINGS, INC.(NASDAQ: SCNX),a holding company for existing and planned pharmaceutical operating companies focused on providing enhanced value to patients, physicians and caregivers through the development, commercialization, and distribution of novel specialty products that address unmet market needs, today announced that it has formalized multiple commercial group purchasing organization (GPO) agreements for ArbliTM(losartan potassium) Oral Suspension, 10 mg/mL, providing access to more than 2500 healthcare institutions, including hospitals, clinics, nursing homes, specialty pharmacies, long-term care facilities, and ambulatory centers, representing potential penetration into an estimated 20% of the U.S. institutional market while also establishing a broad footprint across long-term care and outpatient facilities.

“Securing these GPO agreements is a pivotal milestone for Scienture and for Arbli™,” commented Narasimhan Mani, President and co-CEO of Scienture. “By gaining access to more than 2500 healthcare institutions, we are positioning Arbli™ to reach the patients and providers who need it most. Looking ahead, we plan to further expand our GPO partnerships and direct contracts to deepen institutional market penetration nationwide. This strategy underscores our commitment to creating meaningful growth opportunities and long-term value for shareholders.”

ArbliTMis a novel proprietary formulation of losartan, a widely prescribed angiotensin receptor blocker (ARB) for hypertension.It is the first and only liquid formulation of losartan on the market that does not require compoundingand has reduced dosing volume and long-term shelf life at room temperature storage. ArbliTMis FDA-approved for the treatment of hypertension in patients greater than six years old, for reducing the risk of stroke in patients with hypertension and left ventricular hypertrophy, and for treating diabetic nephropathy in certain patients with type 2 diabetes. By offering a safe, effective, and convenient liquid alternative, Arbli™provides a tailored solution for patients who require or prefer a liquid formulation. As an FDA-approved product, Arbli™ provides consistent quality and dosing accuracy, addressing the risks and inconsistencies often associated with extemporaneously compounded losartan prescriptions. ArbliTMhas two issued patents from the USPTO, which are also listed in the FDA Orangebook.

According to IQVIA data (MAT June 2025), the U.S. losartan market represents approximately $256 million in annual sales and a prescription volume of 71 million (TRx), with all currently marketed products available only in oral solid form.

“GPO agreements often serve as a strategic gateway,” stated Shankar Hariharan, Executive Chairman and co-CEO of Scienture. “Once a product is listed on a contract, it becomes accessible to all member institutions, enabling adoption to scale rapidly without renegotiating individual agreements. These agreements highlight a significant opportunity for Arbli™ as the first FDA-approved, ready-to-use oral suspension.”

ArbliTMis the first and only oral liquid formulation of losartan approved by the U.S. FDA. Arbli™comes in a 165 mL bottle as a peppermint flavored suspension that does not require refrigeration, and has been approved for a shelf life of 24 months from the date of manufacture when stored at room temperature.

ArbliTMis an angiotensin II receptor blocker (ARB) indicated for:

You are encouraged to report negative side effects of prescription drugs to the FDA. Visitwww.fda.gov/medwatch, or call 1-800-FDA-1088. You may also contact Scienture at 1-833-754-4917.

Please see the full Prescribing Information for complete product information. For more information, talk to your healthcare provider.

Hypertension (high blood pressure) is a cardiovascular condition, when the pressure in the blood vessels is too high (140/90 mmHg or higher). According to the CDC, hypertension, or high blood pressure, affects nearly half of adults in the United States, or 119.9 million people. Hypertension is defined as a systolic blood pressure of 140 mmHg or higher, and diastolic blood pressure of 90 mmHg or higher. Hypertension is a risk factor for stroke and heart disease, which are leading causes of death in the U.S. Factors that increase the risk of having high blood pressure include: older age, genetics, being overweight or obese, not being physically active, high-salt diet and drinking too much alcohol. Hypertension is clinically diagnosed if, when blood pressure is measured on two different days, the systolic blood pressure readings on both days is ≥140 mmHg and/or the diastolic blood pressure readings on both days is ≥ 90 mmHg.

SCIENTURE HOLDINGS, INC. (NASDAQ: “SCNX”), through its wholly owned subsidiary, Scienture, LLC, is a comprehensive pharmaceutical product company focused on providing enhanced value to patients, physicians and caregivers by offering novel specialty products to satisfy unmet market needs. Scienture, LLC is a branded, specialty pharmaceutical company consisting of a highly experienced team of industry professionals who are passionate about developing and bringing to market unique specialty products that provide enhanced value to patients and healthcare systems. The assets in development at Scienture are across therapeutics areas, indications and cater to different market segments and channels. For more information please visit:www.scientureholdings.comandwww.scienture.com.

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SCIENTURE HOLDINGS, INC.20 Austin BlvdCommack, NY 11725Phone: (866) 468-6535Email:IR@Scienture.com