Y ea s t: P i chi a pas t or i s IL - 17 is a cytokine that plays a key role in the development of psoriatic lesions, which are in essence an acute, local (dermis) flareup of a chronic underlying disease . It allows for
Friday, September 22, 2023 1 min read
Key Takeaway: The article discusses the role of IL-17, a cytokine, in the formation of psoriatic lesions, highlighting its significance in the inflammatory process associated with psoriasis. It points out the potential for local administration of anti-IL-17 therapies, which may offer a targeted approach to managing this chronic condition. Additionally, the presence of Psoriasin in skin models indicates its relevance to understanding skin inflammation.
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POSITIVE FACTORS
IL-17 plays a key role in the development of psoriatic lesions.
Local administration of anti-IL-17 drugs is possible, targeting the cytokine cascade.
Presence of Psoriasin could be beneficial in understanding skin responses.
Full Press Release Details
10 15 20 30 25 40 70 60 50 85 100 Y ea s t: P i chi a pas t or i s
IL - 17 is a cytokine that plays a key role in the development of psoriatic lesions, which are in essence an acute, local (dermis) flareup of a chronic underlying disease . It allows for local (rather than systemic) administration of anti - IL - 17 drugs to stop the cytokine cascade .
P esence of Pso iasin (S100A7) in an InflammaSkin Model with - Cell activation No induction - cell activation leads to significant inc ease in IL - 17A exp ession healthy ex vivo skin samples of one dono , g owing in a well
10 1 10 2 10 3 10 4 10 5 10 6 Titer [TCID 50 /g] limit of detection 9 8 7 6 5 4 3 2 1 SARS - CoV - 2 RNA copies/ml BALF de t e c t i o n limit
Frequently Asked Questions
What role does IL-17 play in psoriasis?
IL-17 contributes to the development of psoriatic lesions by causing local skin flare-ups.
How can anti-IL-17 drugs be administered?
Anti-IL-17 drugs can be administered locally to effectively halt the cytokine cascade.
What is Psoiasin's significance in inflammation?
Psoiasin (S100A7) increases IL-17A expression in an inflamed skin model.
Where was the research on psoriatic skin conducted?
The research on psoriatic skin models was illustrated on ResearchGate.