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SAB BIO to Present Additional Data Supporting the Unique Profile of SAB-142 at the 2026 Immunology of Diabetes Society Congress

Key Takeaway: SAB Biotherapeutics will present new data on SAB-142 at the upcoming Immunology of Diabetes Society Congress in Brisbane. The presentations will highlight the clinical and mechanistic profile of SAB-142, an innovative immunotherapy for type 1 diabetes. The company anticipates significant engagement with the scientific community as it progresses towards topline data readout in late 2027.
Price reaction · baseline $3.86 (2026-04-14 close) · hit pre-market · clean, no other SABS news in the window
day 0 close · peak
+4.9%

Market Sentiment Analysis

POSITIVE FACTORS

  • SAB-142 shows potential as a best-in-class therapy for T1D.
  • Data presented at the IDS Congress could enhance SAB BIO's reputation.
  • The ongoing SAFEGUARD study indicates active engagement in clinical research.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+144%
120-day peak, hindsight
Typical move
5.9%
average across 3 past catalysts
Cash runway
~29 mo
Minimal dilution risk
Lead asset
SAB-142
Phase 3 · Type 1 Diabetes

Full Press Release Details

MIAMI, April 15, 2026 (GLOBE NEWSWIRE) -- SAB Biotherapeutics, Inc. (Nasdaq: SABS ), a clinical-stage biopharmaceutical company developing a fully human anti-thymocyte immunoglobulin (hATG) for type 1 diabetes (T1D) and other autoimmune diseases, today announced that the Company will give an oral presentation and multiple poster presentations at the 21 st Immunology of Diabetes Society (IDS) Congress being held April 20-24, 2026, in Brisbane, Australia. Data to be presented will highlight SAB BIO’s lead program, SAB-142, a potentially best-in-class, disease-modifying, redosable immunotherapy in clinical development for newly diagnosed Stage 3 T1D patients.
Alexandra Kropotova, M.D., MBA, Chief Medical Officer, SAB BIO, stated, “IDS is an important forum for us to present the breadth of SAB-142's clinical and mechanistic profile. We are pleased to share data on SAB-142's multi-specific binding profile and additional C-peptide data from our patient cohort, which we believe underpins its best-in-class potential. With the SAFEGUARD study now actively enrolling, we look forward to continued engagement with the T1D scientific community as we advance toward our anticipated topline data readout for this study in the 2H 2027.”
Oral Presentation:
Title : Save All Beta Cells: Sustained Autoimmune Balance with SAB-142 Induction and Maintenance Dosing Session: SAB BIO Industry Symposium Presenters: John Wentworth, PhD, FRACP, Professor of Medicine*, Alexandra Kropotova, MD, MBA, Chief Medical Officer, SAB BIO; Christoph Bausch, PhD, MBA, Chief Operating Officer, SAB BIO Presentation Date and Time: Wednesday, April 22, 2026 | 1:00 – 1:45PM AEST Location: Boulevard Auditorium * Dr. Wentworth is an independent guest speaker and is not affiliated with SAB BIO.
Oral Poster Presentations: Title : Multi-specific binding profile of SAB-142, a fully human anti-thymocyte globulin, against T-cell surface proteins Session: Poster Session 1 – Poster #207 Presenter: Christoph Bausch, PhD, MBA, Chief Operating Officer, SAB BIO Presentation Date and Time: Tuesday, April 21, 2026 | 5:30 – 7:00PM AEST Location: Boulevard Foyer
Title : Tracking multiplicity for SAB142: a PBMC based flow cytometry pharmacokinetic assay linking target engagement to clinical exposure Session: Poster Session 1 – Poster #264 Presenter: Eric Sandhurst, PhD, Director, Program Management, SAB BIO Presentation Date and Time: Tuesday, April 21, 2026 | 5:30 – 7:00PM AEST Location: Boulevard Foyer Title : The challenge of blood preservation from multicenter clinical trials: assessing whole blood preservation methods for analysis by flow cytometry Session: Poster Session 2 – Poster #364 Presenter: Eric Sandhurst, PhD, Director, Program Management, SAB BIO Presentation Date and Time: Wednesday, April 22, 2026 | 5:30 – 7:00PM AEST Location: Boulevard Foyer
The presentations will be made available in the Presentations section of the Company’s website at the time of the presentation and will remain accessible following the conference.
About SAB-142 SAB-142 is a potentially disease-modifying, redosable immunotherapy in clinical development for the treatment of autoimmune type 1 diabetes (T1D). SAB-142 is a multi-specific, fully human anti-thymocyte globulin (hATG) with a mechanism of action analogous to that of rabbit ATG (rATG). rATG has demonstrated in multiple clinical trials the ability to slow disease progression in patients with new- or recent-onset of Stage 3 T1D. SAB-142, like rATG, directly targets multiple immune cells involved in destroying pancreatic beta cells, including modulation of “bad acting” T-lymphocytes. By stopping immune cells from attacking beta cells, this treatment has the potential to preserve insulin-producing beta cells.
About SAB BIO SAB BIO is a clinical-stage biopharmaceutical company focused on developing multi-specific, high-potency, human immunoglobulin G (hIgG) to treat and prevent immune and autoimmune disorders. Using advanced genetic engineering and antibody science, SAB BIO developed a proprietary technology which holds the potential to generate additional novel therapeutic candidates utilizing the human immune response, without the need for human donors or convalescent plasma. SAB BIO has optimized genetic engineering in the development of transchromosomic cattle, or Tc-Bovine, to produce hIgG. SAB BIO’s drug development production system is able to generate a diverse repertoire of specifically targeted, high-potency, hIgGs that can address a wide range of serious unmet needs in human diseases. The Company’s lead candidate, SAB-142, targets autoimmune T1D with a disease-modifying therapeutic approach that aims to change the T1D treatment paradigm by delaying onset and potentially preventing disease progression of Stage 3 T1D patients. SAB-142 is currently being evaluated in newly diagnosed Stage 3 autoimmune T1D patients in a registrational Phase 2b clinical trial called SAFEGUARD. For more information, visit www.sab.bio .
Forward-Looking Statements Certain statements made in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995. Forward-looking statements generally are accompanied by words such as “believe,” “may,” “will,” “to be,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” “should,” “would,” “plan,” “predict,” “potential,” “seem,” “seek,” “future,” “outlook,” and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding future events, including statements about the development and clinical trial results of the Company’s T1D program and other discovery programs.
These statements are based on the current expectations of SAB BIO and are not predictions of actual performance, and are not intended to serve as, and must not be relied on, by any investor as a guarantee, prediction, definitive statement, or an assurance, of fact or probability. These statements are only current predictions or expectations, and are subject to known and unknown risks, uncertainties and other factors which may be beyond our control. Actual events and circumstances are difficult or impossible to predict, and these risks and uncertainties may cause our or our industry’s results, performance, or achievements to be materially different from those anticipated by these forward-looking statements. A further description of risks and uncertainties can be found in the sections captioned “Risk Factors” in our most recent annual report on Form 10-K, subsequent quarterly reports on Form 10-Q, as may be amended or supplemented from time to time, and other filings with or submissions to, the U.S. Securities and Exchange Commission, which are available at https://www.sec.gov/. Except as otherwise required by law, SAB BIO disclaims any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events, or circumstances or otherwise.
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Frequently Asked Questions

What is SAB-142?

SAB-142 is a fully human anti-thymocyte immunoglobulin being developed for type 1 diabetes.

When will SAB BIO present data on SAB-142?

SAB BIO will present data at the Immunology of Diabetes Society Congress from April 20-24, 2026.

What is the SAFEGUARD study?

The SAFEGUARD study is a Phase 2b clinical trial evaluating SAB-142 in newly diagnosed Stage 3 T1D patients.

Where will the presentations be held?

The presentations will take place in Brisbane, Australia, during the IDS Congress.

Last updated: Apr 15, 2026