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Rezolute to Host Virtual Investor Event on Ersodetug Development Program

Key Takeaway: Rezolute, Inc. will host a virtual investor event on November 10, 2025, to discuss the development of ersodetug, a treatment for hypoglycemia due to hyperinsulinism. The event will cover the market opportunity and clinical progress of ersodetug, currently in two Phase 3 studies. Key insights will be shared by Rezolute's management and hyperinsulinism experts.
Price reaction · baseline $8.9 (2025-11-04 close) · hit pre-market · 3 other RZLT headline(s) in the window, move may be shared
day 0 close
+5.1%
day 1
+7.9%
day 3 · peak
+11.9%

Market Sentiment Analysis

POSITIVE FACTORS

  • Rezolute is hosting a virtual investor event to discuss ersodetug.
  • Ersodetug shows potential in treating hypoglycemia from various causes.
  • Upcoming Phase 3 studies are expected to yield important results.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+183%
120-day peak, hindsight
Typical move
5.3%
average across 2 past catalysts
Cash runway
~23 mo
Low dilution risk
Lead asset
Experimental: Group 1- RZ402
Phase 2 · Diabetic Macular Edema

Full Press Release Details

REDWOOD CITY, Calif., Nov. 05, 2025 (GLOBE NEWSWIRE) --Rezolute, Inc. (Nasdaq: RZLT) (“Rezolute” or the “Company”), a late-stage rare disease company focused on treating hypoglycemia caused by hyperinsulinism, today announced that the company will host a virtual investor event via webcast on Monday, November 10, 2025, from 12:00 – 1:30 pm EST. The event will highlight the market opportunity and clinical development of ersodetug, which is currently being evaluated in two Phase 3 studies in congenital hyperinsulinism (HI) and tumor HI, respectively.
During the event, Rezolute Chief Commercial Officer, Sunil Karnawat, will discuss the anticipated commercial opportunities for ersodetug as a potential treatment for congenital and tumor HI. In addition, Rezolute management will review the Company’s ongoing clinical development programs, including the Phase 3 sunRIZE study in congenital HI, with topline results expected in December 2025, and the Phase 3 upLIFT study in tumor HI.
The call will also feature remarks from two leading hyperinsulinism experts:
The physicians will discuss the significant unmet medical need, patient profiles, and current treatment landscape for each indication.

Conference Call Information

To access the event by phone, please dial 1-877-317-6789 from the U.S. and Canada or 1-412-317-6789 internationally and ask to be joined into the Rezolute call. The live webcast can be accessed on the investor page of Rezolute’s website at https://ir.rezolutebio.com. A replay of the webcast will be available approximately two hours after the completion of the event.

About Ersodetug

Ersodetug is a fully human monoclonal antibody that binds allosterically to the insulin receptor to decrease receptor over-activation by insulin and related substances (such as IGF-2) in the setting of hyperinsulinism (HI), thereby improving hypoglycemia. Because ersodetug acts downstream from the pancreas, it has the potential to be universally effective at treating hypoglycemia due to any congenital or acquired form of HI.

About Rezolute, Inc.

Rezolute is a late-stage rare disease company focused on treating hypoglycemia caused by hyperinsulinism (HI). The Company’s antibody therapy, ersodetug, is designed to treat all forms of HI and has shown meaningful benefit in clinical trials and real-world use for the treatment of both congenital and tumor HI. For more information, visit www.rezolutebio.com.

Rezolute Contacts:

Frequently Asked Questions

When is Rezolute's virtual investor event?

The event is scheduled for November 10, 2025, from 12:00 to 1:30 pm EST.

What is the focus of the investor event?

The event will highlight the market opportunity and clinical development of ersodetug.

What studies is ersodetug currently involved in?

Ersodetug is being evaluated in two Phase 3 studies for congenital and tumor hyperinsulinism.

Who will speak at the investor event?

Rezolute's Chief Commercial Officer and leading hyperinsulinism experts will present.

How can I access the virtual event?

You can access the event via phone or live webcast on Rezolute's investor page.

Last updated: Nov 5, 2025