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Rezolute Reports Full Year Fiscal 2023 Results and Highlights Company Progress Planning to initiate Phase 3 Study for RZ358 ("sunRIZE study") in the fourth quarter of 2023

Key Takeaway: Rezolute, Inc. reported its financial results for the full fiscal year 2023, highlighting plans to initiate the Phase 3 study called sunRIZE for RZ358 in the fourth quarter. The CEO expressed optimism about reaching important milestones, including the anticipated results from a Phase 2 study of RZ402 in early 2024. Despite the positive developments, the company faced challenges, including a significant financial loss and a decrease in cash reserves compared to the previous year. Rezolute continues its mission to develop therapies for debilitating metabolic diseases.

Market Sentiment Analysis

POSITIVE FACTORS

  • Rezolute is set to initiate the Phase 3 study for RZ358, indicating progress in their clinical development.
  • The company anticipates results from the Phase 2 study of RZ402 in early 2024, showing ongoing development efforts.
  • Rezolute remains committed to transformative therapies that aim to disrupt treatment paradigms for metabolic diseases.

CONCERNS & RISKS

  • The company reported a significant net loss for both the fourth quarter and full year of fiscal 2023.
  • There is a potential risk associated with the uncertainty of clinical trial results and their impact on future performance.
  • Rezolute's cash and cash equivalents showed a notable decline from the previous year, raising concerns about financial stability.

Full Press Release Details

Rezolute Reports Full Year
Fiscal 2023 Results and Highlights Company Progress
Planning to initiate Phase 3 Study for RZ358 ("sunRIZE study")
in the fourth quarter of 2023
REDWOOD CITY, Calif., Sept. 14, 2023 (GLOBE NEWSWIRE) -- Rezolute,
Inc. (Nasdaq: RZLT), a clinical-stage biopharmaceutical company dedicated to developing transformative therapies with the potential to
disrupt treatment paradigms for devastating metabolic diseases, today announced its financial results for the fourth quarter and full
fiscal year ended June 30, 2023.
"We are delighted that we are poised to initiate sunRIZE -- our
Phase 3 study of RZ358, which we hope will bring us one step closer to making this therapy available to patients and their families suffering
from congenital hyperinsulinism. We are also anticipating results from our Phase 2 study of RZ402 in the first quarter of 2024, where
we hope to demonstrate the safety and proof-of-concept of our oral therapy for diabetic macular edema," said Nevan Charles Elam,
Chief Executive Officer and Founder of Rezolute. "As we look ahead to these upcoming milestones, we remain committed to our mission
of delivering transformative therapies to patients with devastating metabolic diseases."
Corporate and Clinical Highlights
Fourth Quarter and Full Year Fiscal 2023 Financial Results
About Rezolute, Inc.
to disrupt current treatment paradigms by developing transformative therapies for devastating rare and chronic metabolic diseases. Its
novel therapies hold the potential to both significantly improve outcomes and reduce the treatment burden for patients, the treating
physician, and the healthcare system. Patient, clinician, and advocate voices are integrated in the Company's drug development
process, enabling Rezolute to boldly address a range of severe conditions. Rezolute is steadfast in its mission to create profound, positive,
and lasting impact on patients' lives. The Company's lead clinical asset, RZ358, is in late-stage development for the treatment
of congenital hyperinsulinism, a rare pediatric endocrine disorder. Rezolute is also developing RZ402, an orally available plasma kallikrein
Twitter or LinkedIn.
Forward-Looking Statements
The information provided herein contain "forward-looking
statements" within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. Forward-looking
statements can be identified by words such as "anticipate," "intend," "plan," "goal," "seek,"
"believe," "project," "estimate," "expect," "strategy," "future," "likely,"
"may," "should," "will" and similar references to future periods. The "forward-looking statements" include, but are not limited to, statements regarding receiving results from the Phase 2
study of RZ402 in the first quarter of 2024, the ability of RZ358 to treat congenital hyperinsulinism, the timing of the release topline
results from sunRIZE, and our ability to meet trial enrollment goals.
Forward-looking statements are neither
historical facts nor assurances of future performance. Instead, they are based only on Rezolute's current beliefs, expectations
and assumptions regarding the future of its businesses, results of and timing of clinical trials, financial condition and results of
operations, future plans and strategies, projections, anticipated events and trends, the economy and other future conditions. Because
forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that
are difficult to predict and many of which are outside of Rezolute's control. Rezolute's actual results including the timing
and results of clinical trials may differ materially from those indicated in the forward-looking statements. Therefore, you should not
place undue reliance on any of these forward-looking statements. Important factors that could cause Rezolute's actual results including
the timing and results of clinical trials to differ materially from those indicated in the forward-looking statements are discussed or
identified in Rezolute's filings made with the U.S. Securities and Exchange Commission. Any forward-looking statements made by
Rezolute in this information are based only on information currently available to Rezolute and speak only as of the date on which the
statement is made. Rezolute undertakes no obligation to update any forward-looking statement, whether written or oral, that may be made
from time to time, whether as a result of new information, future developments or otherwise except as required by applicable law.
Consolidated Financial Statements Data
thousands, except per share data)
Three Months Ended Year Ended
June 30, June 30,
2023 2022 2023 2022
Condensed Consolidated Statements of Operations Data:
Operating expenses:
Research and development $ 10,933 $ 8,574 $ 43,813 $ 32,486
General and administrative 3,305 2,725 12,177 9,357
Total operating expenses 14,238 11,299 55,990 41,843
Loss from operations (14,238 ) (11,299 ) (55,990 ) (41,843 )
Non-operating income (expense), net 1,510 1,876 4,203 783
Net loss $ (12,728 ) $ (9,423 ) $ (51,787 ) $ (41,060 )
Net loss per common share
Basic $ (0.25 ) $ (0.30 ) $ (1.01 ) $ (2.26 )
Diluted $ (0.25 ) $ (0.37 ) $ (1.01 ) $ (2.32 )
Weighted average number of common shares outstanding:
Basic 51,410 31,429 51,188 18,197
Diluted 51,410 36,302 51,188 19,487
June 30, June 30,
2023 2022
Condensed Consolidated Balance Sheets Data:
Cash and cash equivalents $ 16,036 $ 150,410
Investments in marketable debt securities 102,330 -
Working capital 99,710 149,642
Total assets 123,721 152,420
Accumulated deficit (260,984 ) (209,198 )
Total stockholders' equity 123,721 149,471

Frequently Asked Questions

What is the sunRIZE study?

The sunRIZE study is a planned Phase 3 clinical trial for RZ358 targeting congenital hyperinsulinism.

When will Phase 3 study for RZ358 begin?

The Phase 3 study for RZ358 is expected to start in the fourth quarter of 2023.

What is RZ402 being evaluated for?

RZ402 is being studied for its safety and efficacy in treating diabetic macular edema.

What were Rezolute's FY2023 financial results?

Rezolute reported a net loss of $51.8 million for fiscal year 2023.

What is Rezolute's mission?

Rezolute aims to develop transformative therapies for rare and chronic metabolic diseases.

Last updated: Sep 14, 2023