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Key Takeaway: JEFFERIES 2017 GLOBAL HEALTHCARE CONFERENCE Dan Browne PRESIDENT AND CEO JUNE 2017 Exhibit 99.1 Forward-Looking Statements / Safe Harbor This presentation contains forward-looking statements, including statements related to: our financial outlook and other financial performanc

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JEFFERIES 2017 GLOBAL HEALTHCARE
CONFERENCE Dan Browne PRESIDENT AND CEO JUNE 2017 Exhibit 99.1
Forward-Looking Statements / Safe
Harbor This presentation contains forward-looking statements, including statements related to: our financial outlook and other financial performance; the process and timing of anticipated future clinical development of our product candidates; our
business strategy, goals, plans and prospects; timing and outcome of our clinical trials; our ability to obtain regulatory approval; the potential therapeutic and economic benefits and value of our product candidates and our technologies; demand for
our product candidates and drivers of demand; market size, adoption rate and potential revenue; growth opportunities and product pipeline; our ability to leverage our investment in our development and manufacturing platform; and our intellectual
property strategy. Forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially from our expectations. These risks and uncertainties include, but are not limited to: the outcome, cost and
timing of our product development activities and clinical trials; the uncertain clinical development process, including the risk that clinical trials may not have an effective design; our ability to obtain and maintain regulatory approval of our
product candidates; our ability to obtain funding for our operations; our plans to research, develop and commercialize our product candidates; our ability to achieve market acceptance of our product candidates; unanticipated costs or delays in
research, development and commercialization efforts; the applicability of clinical study results to actual outcomes; the size and growth potential of the markets for our product candidates; our ability to successfully commercialize our product
candidates and the timing of commercialization activities; the rate and degree of market acceptance of our product candidates; our ability to develop sales and marketing capabilities; the accuracy of our estimates regarding expenses, future
revenues, capital requirements and needs for financing; and our ability to continue obtaining and maintaining intellectual property protection for our product candidates. These and other risks are described in the "Risk Factors" section
of our Form 10-Q filed with the Securities and Exchange Commission on May 9, 2017. The "Risk Factors" section of 10-Q speaks only as of the date thereof. These forward-looking statements speak only as of the date hereof or the date
specified. Revance disclaims any obligation to update these forward-looking statements. "Revance Therapeutics", TransMTS, "Remarkable Science Changes Everything", and the Revance logo are registered trademarks of Revance
Therapeutics, Inc. All other trademarks or registered trademarks are the property of their respective owners.
PRE-COMMERCIAL BIOTECHNOLOGY COMPANY
LONG-DURATION, NEXT GENERATION NEUROMODULATOR REMARKABLE SCIENCE MEDICAL AESTHETICS THERAPEUTICS ADDRESSING $3B+ MARKETS Nerves Muscle
THERAPEUTICS MEDICAL AESTHETICS
Insurance and out-of-pocket pay ... sweaty palms ... migraine ... foot pain ... urinary urge/incontinence ... depression ... heart trouble ... TMJ/teeth grinding Out-of-pocket pay Several currently approved indications ... nasolabial folds ...
wrinkles ... marionette lines ... neck lines ... frown lines ... crows feet rosacea acne The Vast Potential of Neuromodulators and 700+ Other Conditions * Source: Global Industry Analysts, Inc. Botulinum Toxin -
A Strategic Business Report, Sept. 2016 the drug that's treating everything. Neuromodulators " " $3B+ TODAY* $6B+ by 2022* ... neck spasms
The Challenge of Today's
Neuromodulators / Toxins Does it work as intended? Could it work BETTER? Higher response rates How long does it last before effect fades? Could it last LONGER? 6 months vs. 3 months Are there potential adverse side effects? Could it be SAFER?
Even at higher doses EFFICACY SAFETY DURATION
Our Differentiated Neuromodulator One
THERAPEUTIC AGENT Patented Peptide Technology DaxibotulinumtoxinA Positively charged peptide that binds with negatively charged area of molecule. NO animal-derived components or human albumin Highly purified, botulinum toxin type A molecule
Potential for Better, Longer, Safer Treatment DaxibotulinumtoxinA for Injection (RT002) DaxibotulinumtoxinA Topical Gel (RT001) Two DAXI' MODALITIES In late-stage development Designed to be long lasting, injectable neuromodulator In
preclinical development Designed to offer topical delivery of botulinum toxin Current Focus Unique EXCIPIENT +
First New Neuromodulator Product in
nearly 30 years, demonstrating PROMISING SAFETY, hIGH Response Rates & LONG Duration Preparing to Commercialize in ~$1B* Glabellar Line Market Addressing >$3B Markets in aesthetic & therapeutic applications Multiple near-term catalysts in
2017 Existing funding expected to last through 2018 - $189 million at 03/31/17 * Company estimate for FY 2015 based on Specialty Pharmaceuticals Monthly Handbook, UBS Global Research, January 2016 Company Highlights
Our Two-Pronged Path, Aesthetics and
Therapeutics BUILD Infrastructure and DRIVE Commercial Excellence Lead Program: Experience in 1,200 patients by end of 2017; file for US marketing approval in 2019 AESTHETICS LEVERAGE Infrastructure and BUILD Therapeutic Portfolio THERAPEUTICS
Progressing in Three Important
Indications INDICATION GLABELLAR LINES CERVICAL DYSTONIA PLANTAR FASCIITIS Demonstrating use in ... SMALL Muscles LARGE Muscles SMOOTH Muscles Stage Phase 3 Phase 2 Phase 2 Potential Differentiation LONG TIME between treatments - Safe and
effective SAFE at the high doses required in large muscles FIRST approved neuromodulator in indication. Targeting pain and inflammation LONG DURATION AND HIGH RESPOSE RATES 1 Most Advanced 2 On-Deck 3 Next Up AESTHETICS THERAPEUTICS
Significant Market Potential in Our
Initial Indications > $2B Market Opportunity The Strategy: Capture and Build on the Opportunity ...with enhanced neuromodulator Expand indications Grow the Market Target largest segments Take Share 1 GLABELLAR LINES 2 CERVICAL DYSTONIA 3 PLANTAR
FASCIITIS NEW pain and inflammation indication in Therapeutic market Part of $1B muscle movement disorders segment, LARGEST in Therapeutics ~$1B global sales; single LARGEST neurotoxin segment in Aesthetics AESTHETICS THERAPEUTICS
1. Glabellar Lines: Largest
Aesthetic Treatment Area Significant Unmet Need for Longer Duration of Effect and Higher Response Rates Versus Currently Available Treatments Current treatments have 3-4 month duration of effect Plan to explore application to other areas of the face
UNMET NEED Phase 2 (BELMONT) Achieved Trifecta: Efficacy, Safety and Duration (BELMONT) n=268; Reported 2015 Achieved 6 month duration of effect Appeared safe with high response rates STATUS Phase 3 Underway Pivotal trials fully enrolled n=300 (x 2
pivotals) + 1,500 (LT safety) Results in Q4 2017 ~$1B Global Frown Lines Market THE CONDITION
BELMONT Phase 2 Study: Positive
Efficacy and Safety Source: IMCA's 2017 BELMONT Bertucci Short Draft *Vistabel / Botox Cosmetics EFFICACY SAFETY Excellent Overall Profile (Mean duration 47 days) Headache Erythema Ptosis (Eyelid Droop) MOST COMMON AEs % with
1 Point Improvement (IGA-FWS) DESIGN Location: Multiple centers; Canada Patients: n=268 all with moderate/ severe Glabellar lines Dosing: Placebo; RT002 (20, 40, 60 units); Botox* (20 units) RT002 60U (n=41) RT002 40U (n=39 RT002 20U (n=34)
Onabot 20U (n=42) Placebo (n=35) 90% 54% 32% 19% 18% 79%* 59%* 36% 83%* 68% 44% *p=<0.05 vs Onabot 20U *
SCORES Investigation IGA-FWS 2 0 0
Patient PFWS 2 0 0 BELMONT: 6-Month Duration of Effect Achieved - Patient Example PRE-TREATMENT (Baseline) WEEK 4 6 MONTHS DaxibotulinumtoxinA 40 Units Moderate Wrinkles No Wrinkles No Wrinkles
BELMONT P2 Study: Superior Duration
of Response Over BOTOX in Every Dose Duration of Response for at Least a 1-point Improvement from Baseline for IGA-FWS Assessment at Maximum Frown (Per-Protocol Population) % of Subjects PLACEBO Weeks RT002 40U RT002 60U RT002 20U BOTOX 20U
Median Duration (Weeks) 23.6 20.9 20.0 18.8 p=0.030
Preparing for U.S. Launch -
RT002 Injectable Glabellar Lines Pivotal Trials Fully Enrolled Randomized, double-blind, placebo-controlled trial at 60+ sites in U.S. and Canada, measuring safety, efficacy, and duration of effect for a single treatment of RT002 600 patients with
moderate to severe glabellar lines (SAKURA 1 & 2) Up to 1,500 patients enrolled in long-term safety study (SAKURA 3) Endpoints: Composite primary endpoint % of subjects achieving score of 0/1 (none/mild) and a two-point improvement from baseline
in glabellar lines severity on IGS-FWS and PFWS at maximum contraction at week 4 Secondary endpoint Duration of reduction in severity 2018 SAKURA 2 Topline Data Q4 2017 SAKURA 1 Topline Data Q4 2017 BLA Filing 2019 SAKURA 3 Safety Data U.S. Approval
& Launch 2019/20 Ex-U.S. Approval & Launch 2020+ PHASE 3 Evaluating Potential Ex-U.S. Partners MILESTONES
BELMONT Data Analyzed Using Phase 3
Endpoints Composite of Subjects with None or Mild and 2 Point Change from Baseline on IGA-FWS and PFWS (Week 4) Per-Protocol Analysis Intent-to-Treat Analysis P <.001 BELMONT Data SAKURA Primary Endpoint 4 point scale; Per-protocol
population BELMONT Data Percentage of Subjects with Severity of None or Mild Investigator Assessment (IGA-FWS) Week Daxibot 40U Placebo 2 97.3%** 2.9% 4 97.4%** 0.0% 8 97.4%** 0.0% 12 84.6%** 0.0% 16 66.7%** 0.0% 20 46.2%** 0.0% 24 30.8%** 0.0%
Patient Assessment (PFWS) Week Daxibot 40U Placebo 2 91.9%** 0.0% 4 94.9%** 0.0% 8 86.8%** 0.0% 12 84.6%** 0.0% 16 61.5%** 0.0% 20 35.9%** 0.0% 24 20.5%* 0.0% *p<.01 versus placebo; **p<.001 versus placebo SAKURA Secondary Efficacy
2. Cervical Dystonia: Largest Muscle
Movement Disorder UNMET NEED Currently Available Treatments and Therapies Include Oral Medications, Botulinum Toxin Injections, and Surgery Deeper, targeted botulinum toxin delivery is required Significant unmet need for longer duration THE
CONDITION Painful/debilitating twisting movements of neck and shoulders Large impact on quality of life ~$1B Global Muscle Movement Disorder Market 2015 STATUS Phase 2 Study Achieved Trifecta: Efficacy, Safety and Duration Topline results announced
May 2017 U.S. 24 week, Open-label, Sequential Dose-escalating, Multicenter: 37 patients ~10x dose of glabellar lines treatment Endpoint Primary: Change from baseline in Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) -Total Score over
Phase 2 Cervical Dystonia -
All Cohorts EFFICACY SAFETY* Most Frequent AEs (week 24) Other Toxins to Treat CD: Dysphagia 13-35% Note: All Subjects with values at both Baseline and Week 4 (n=35). Subjects with a missing value for either Baseline or Week 4 are excluded from the
summary. RT002 is an investigational product 38% 34% 42% 41% Score Baseline Week 4 Clinically Significant Reduction of 38% Across All Subjects Safe and Well-Tolerated: No SAEs Primary Endpoint: Reduction in TWSTRS Score (week 4) 1 All cases of
dysphagia were mild in severity 2 Muscle weakness included a mild (cervical paraspinal) and a moderate (cervical extensor) case 1 2
Phase 2 Cervical Dystonia: Subject
Distribution by Dose Number of Subjects CD Phase 2 week 24 results, May 2017 Cohort 1 (n=12) Cohort 2 (n=12) Cohort 3 (n=13) LOW Dose Group 100U-240U n=21 HIGH Dose Group 300U-450U n=16 Cohort 1 Cohort 2 Cohort 3
Phase 2 Cervical Dystonia: Overall
Response and Duration Duration of Response Overall Response Rate (Week 4; n=35) (In Maintaining 20% of Treatment Effect Achieved at Week 4*) Percent of Subjects Scores 1 Clinical Global Impression of Change (CGIC) Score 1
Patient Global Impression of Change (PGIC) Score 1 % Subjects Weeks Median Duration of Response of 24 Weeks Observed Across All Dose Groups 100-240U (n=20) 300-450U (n=16) All Subjects (n=36) *Of subjects with improvement at week 4.
Withdrawals due to need to retreatment are considered as events.
Duration of Response in Cervical
Dystonia: RT002 and Dysport *Poewe W. et al. Efficacy and safety of abobotulinumtoxinA liquid formulation in CD: a randomized controlled trial. Movement Disorders, 2016. The Dysport trademark is used under license by Galderma Laboratories, L.P. FIG.
2. Mean change from baseline in TWSTRS total scores for patients (intention-to-treat population) treated with abobotlinumtoxinA solution for injection (ASI) compared with abobotulinumtoxinA (ABO) and placebo in cycle 1. Phase 3 TRIAL: DYSPORT Weeks
*p<0.05; **p<0.005; ***p<0.0001 versus placebo Week 8: Peak Benefit (32-35% Reduction) Week 12: Majority of Benefit Lost (11-13% Reduction) * * ** ** * *** *** Placebo ASI 500U ABO 500U Mean Change from Baseline in TWSTRS Total Score Phase
2 TRIAL: RT002 Mean Change from Baseline in TWSTRS Total Score Weeks 6 9
THE CONDITION 3. Plantar Fasciitis:
Highly Prevalent Foot/Heel Disorder 1 in 10 People will develop Plantar Fasciitis in their lifetime 2M+ patients in U.S. undergo treatment annually UNMET NEED No Neurotoxin Currently Approved to Treat Plantar Fasciitis Current treatments: NSAIDs,
shoe inserts, steroid injections, shock wave therapy, platelet rich plasma injections, and/or surgery Botulinum toxin may provide fast, sustained pain relief and support healing of the plantar fascia STATUS U.S. Phase 2 Trial Actively Enrolling
Prospective, randomized, double-blind, multi-center, placebo-controlled trial measuring safety and efficacy of a single treatment 60 Patients - Entry Criteria 18 to 65 years of age Diagnosis of unilateral plantar faciitis Persistent heel pain
for more than three months Endpoints Primary: Reduction in Visual Analog Scale (VAS) for pain in the foot Secondary: Reduction in AOFAS Function Score Results Expected in Q4 2017 $250M+ US Plantar Fasciitis Market 2015
Specialty sales forces focused on
Dermatologists and Plastic Surgeons SALES Targeted effort: brand development, conversion and expansion MARKETING Publication and physician outreach; medical education DEVELOPMENT Unlimited capacity for drug substance; stable product; commercial
scale MANUFACTURING OPERATIONS Readying Our Commercial Infrastructure for Aesthetics Launch LEADERSHIP TEAM Expanding senior commercial team / capability
Proven Team with Deep Experience
Assembling a Commercial Team of Industry Veterans DAN BROWNE Co-Founder, President & CEO >30 years pharmaceutical and medical technology experience Various leadership roles in product development, sales, and marketing ABHAY JOSHI, PH.D.,
M.B.A. COO >30 years global pharmaceutical and biotech experience in various leadership roles Extensive oversight of botulinum toxin development, strategy and operations LAUREN SILVERNAIL CFO and CBO >30 years finance and business development
experience M&A and transactional experience in leadership roles ROMAN G. RUBIO, M.D. SVP, Clinical Development >15 years of drug development experience Early and late stage product development, medical affairs, and physician relations MUKUL
AGARWAL VP, Business Development >15 years drug development and commercialization experience M&A, licensing, JV transaction expertise ERICA BAZERKANIAN Head, Strategic Marketing >20 years of experience in healthcare marketing Has led brand
and new product development, strategic market planning, and product launches REVANCE EXPERTISE Launch and Commercialization Clinical Development/Regulatory Manufacturing
RT002 INJECTABLE RT001 TOPICAL
CERVICAL DYSTONIA PLANTAR FASCIITIS Hyperhidrosis Migraine Shingles & Inflammatory Diseases Neuropsychiatric Disorders Limb Spasticity Migraine Overactive Bladder Musculoskeletal Disorders TMJ/Teeth Grinding Neuropsychiatric Disorders
THERAPEUTICS GLABELLAR LINES RT002 INJECTABLE RT001 TOPICAL Rosacea Above the Lip Neck / D colletage Lateral Canthal Lines Masseter (Face Shaping) Forehead Lines AESTHETICS "Pipeline in a Product" Significant Growth from Potential
New Indications Longer Duration Higher Response Rates Daxibotulinum- toxinA = Our "Beachhead" Today
Global Commercialization Right and
Expansive IP Coverage COMMERCIALIZATION RIGHTS INTELLECTUAL PROPERTY 183 issued patents with 134 patents applications pending Core US composition and methods patents expire in 2027 and 2029 Potentially extendable for up to 5 years Acquired more than
Last updated: Jun 6, 2017