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How Skipping The CRO Helped RenovoRx Get Closer To Patients

Key Takeaway: RenovoRx has opted to conduct its Phase 3 TIGer-PaC trial without a CRO, leveraging in-house expertise. Chief Clinical Officer Leesa Gentry discusses how this decision enhances patient engagement and streamlines trial execution. The trial focuses on delivering chemotherapy directly to patients with locally advanced pancreatic cancer.
Price reaction · baseline $1.23 (2025-09-23 close) · hit pre-market · 4 other RNXT headline(s) in the window, move may be shared
day 0 close
-2.4%

Market Sentiment Analysis

POSITIVE FACTORS

  • RenovoRx's decision to skip a CRO has streamlined their trial process.
  • The in-house expertise allows for closer patient engagement.
  • The trial aims to improve treatment for pancreatic cancer patients.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+57%
120-day peak, hindsight
Typical move
12.3%
average across 4 past catalysts
Cash runway
~10 mo
Medium dilution risk
Lead asset
nab-paclitaxel
Phase 3 · Locally Advanced Pancreatic Cancer

Full Press Release Details

A conversation with Leesa Gentry, chief clinical officer, RenovoRx Most clinical trials involve three core parties in their execution: the sponsor, the site, and the CRO. Recently, this approach has maintained dominance, but from time to time, sponsor preferences change their approach and take execution of the trial into their own hands.
Such is the case with RenovoRx and TIGer-PaC, its Phase 3 head-to-head superiority trial for RenovoCath, which delivers chemotherapy intra-arterially instead of standard of care IV administration for those with locally advanced pancreatic cancer.
In this Q&A, RenovoRx Chief Clinical Officer Leesa Gentry explains why they decided to forgo a CRO partner, discusses their in-house expertise, and shares how the decision helped them get closer to patients.
View the entire article on Clinical Leader

Frequently Asked Questions

What is the TIGer-PaC trial?

The TIGer-PaC trial is a Phase 3 head-to-head superiority trial for RenovoCath.

Why did RenovoRx skip the CRO?

RenovoRx chose to skip the CRO to utilize their in-house expertise and enhance patient engagement.

What is RenovoCath?

RenovoCath is a treatment that delivers chemotherapy intra-arterially for pancreatic cancer.

Who is Leesa Gentry?

Leesa Gentry is the Chief Clinical Officer at RenovoRx.

Last updated: Sep 24, 2025