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Avidity Biosciences to Host Investor and Analyst Event Focused on AOC 1001 Topline Data from Phase 1/2 MARINA™ Trial on April 27, 2023

Key Takeaway: Avidity Biosciences will host an investor and analyst event on April 27, 2023, in Boston, to present topline data from its AOC 1001 Phase 1/2 MARINA trial targeting myotonic dystrophy type 1. The event, featuring lead investigator Nicholas E. Johnson, will be available via webcast, ensuring broader access to the findings. This marks the seventh volume of Avidity's ongoing series aimed at engaging with investors and analysts regarding their clinical developments in RNA therapeutics.
Price reaction · baseline $13.99 (2023-04-12 close) · hit after-hours · 1 other RNA headline(s) in the window, move may be shared
day 0 close
+9.1%
day 1
+7.1%
day 3 · peak
+15.2%

Market Sentiment Analysis

POSITIVE FACTORS

  • Upcoming presentation of AOC 1001 topline data suggests transparency and engagement with stakeholders.
  • Event indicates progress in clinical trials for myotonic dystrophy type 1.
  • Avidity's innovative approach using Antibody Oligonucleotide Conjugates may represent a significant advancement in RNA therapeutics.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Cash runway
~201 mo
Minimal dilution risk
Lead asset
Durvalumab
Phase 2 · Lung Cancer Stage II

Full Press Release Details

Nicholas E. Johnson, M.D., M.Sci., FAAN, MARINA lead investigator will present AOC 1001 topline data
Volume 7 of investor and analyst series will be an in-person event in Boston and available via webcast
SAN DIEGO, April 13, 2023 /PRNewswire/ -- Avidity Biosciences, Inc. (Nasdaq: RNA), a biopharmaceutical company committed to delivering a new class of RNA therapeutics called Antibody Oligonucleotide Conjugates (AOCs™), today announced that the company will host Volume 7 of its investor and analyst series focused on the topline safety, biomarker and functional data from the AOC 1001 Phase 1/2 MARINA™ trial in adults with myotonic dystrophy type 1 (DM1) on April 27, 2023 at 5:30 p.m. ET in Boston and available via webcast.
(PRNewsfoto/Avidity Biosciences, Inc.)
The Avidity management team will be joined by Nicholas E. Johnson, MD, MSCI, FAAN, Vice Chair for Research, Department of Neurology, Virginia Commonwealth University. Dr. Johnson is presenting the topline data for the first time earlier that day during an oral presentation at the 75th American Academy of Neurology (AAN) Annual Meeting.
Dr. Johnson is one of the principal investigators in END-DM1, an ongoing natural history study being run by the Myotonic Dystrophy Clinical Research Network (DMCRN) and is the lead investigator in the AOC 1001 Phase 1/2 MARINA trial.
In-person and Video Webcast Information
The company is hosting Volume 7 of its investor and analyst event series on April 27, 2023 in Boston, beginning at 5:30 p.m. ET to discuss the topline data from the MARINA trial of AOC 1001. The event will be available via a live video webcast and can be accessed here or from the "Events and Presentations" page in the "Investors" section of Avidity's website. A replay of the webcast will be archived on Avidity's website following the event.
Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs™). Avidity's proprietary AOCs are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to target the root cause of diseases previously untreatable with RNA therapeutics. Avidity's advancing and expanding pipeline has three programs in clinical development. AOC 1001 is designed to treat people with myotonic dystrophy type 1 (DM1) and is currently in Phase 1/2 development with the ongoing MARINA™ and MARINA-OLE™ trials. AOC 1020 is designed to treat people living with facioscapulohumeral muscular dystrophy (FSHD) and is currently in Phase 1/2 development with the FORTITUDE™ trial. AOC 1044 is designed for people with Duchenne muscular dystrophy (DMD) mutations amenable to exon 44 skipping and is currently in Phase 1/2 development with the EXPLORE44™ trial. AOC 1044 is the first of multiple AOCs the company is developing for DMD. Avidity is also broadening the reach of AOCs beyond muscle tissues through both internal discovery efforts and key partnerships as the company continues to deliver on the RNA revolution. Avidity is headquartered in San Diego, CA. For more information about our science, pipeline and people, please visit www.aviditybiosciences.com and engage with us on LinkedIn and Twitter.

Frequently Asked Questions

What is the focus of Avidity Biosciences' April 27 event?

The event focuses on topline safety, biomarker, and functional data from the AOC 1001 trial.

Who will present the AOC 1001 data?

Dr. Nicholas E. Johnson will present the topline data for the first time.

Where is the investor event being held?

The investor event will take place in Boston and will also be available via webcast.

What company is behind the AOC therapeutics?

Avidity Biosciences, Inc. is the company developing the Antibody Oligonucleotide Conjugates.

What diseases are targeted by Avidity's programs?

Avidity's programs target myotonic dystrophy, facioscapulohumeral muscular dystrophy, and Duchenne muscular dystrophy.

Last updated: Apr 13, 2023