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Rani Therapeutics to Present Clinical and Preclinical Data on Oral Delivery of an Ustekinumab Biosimilar via the RaniPill Capsule at Digestive Disease Week 2024

Key Takeaway: Rani Therapeutics will present clinical and preclinical data on its RaniPill capsule, which delivers an ustekinumab biosimilar, at Digestive Disease Week 2024. The sessions include a late-breaking oral presentation on the safety and bioavailability of the drug in humans, and a poster session on the drug's efficacy in canines. This event is a significant opportunity for Rani Therapeutics to demonstrate its innovative technology and findings to a large audience of medical professionals.
Price reaction · baseline $7.15 (2024-05-08 close) · hit after-hours · 1 other RANI headline(s) in the window, move may be shared
day 0 close
-5.2%
day 1
-11.7%
day 3 · peak
-19.2%

Market Sentiment Analysis

POSITIVE FACTORS

  • Rani Therapeutics is showcasing innovative oral delivery of biologics.
  • The RaniPill capsule has demonstrated reliability and safety in human trials.
  • Presentation at a major conference highlights the importance of the findings.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Cash runway
~18 mo
Low dilution risk
Lead asset
Stelara
Phase 1 · Healthy Volunteers

Full Press Release Details

SAN JOSE, Calif., May 09, 2024 (GLOBE NEWSWIRE) -- Rani Therapeutics Holdings, Inc. (“Rani Therapeutics” or “Rani”) (Nasdaq: RANI), a clinical-stage biotherapeutics company focused on the oral delivery of biologics and drugs, today announced that it will present clinical and preclinical and data on the RaniPill® capsule, the company’s oral delivery platform, at Digestive Disease Week® (DDW) taking place both virtually and in-person on May 18-21, 2024 in Washington, DC.
Details of the presentations are as follows:
Abstract Title: An Orally Administered Robotic Pill (RP) Reliably and Safely Delivers an Ustekinumab Biosimilar RT-111 with High Bioavailability Relative to Subcutaneous (SC) Ustekinumab in Healthy Human Participants
Session Type: Late-Breaking Oral Presentation
Session Title: IMIBD Late Breakers and Innovations in IBD
Session Date & Time: May 19, 2024 from 2:00 – 3:30 EDT
Presentation Time: 3:00 PM to 3:15 PM EDT
Session Number: 3465
Presenting Author: Jacques Van Dam, MD, PhD
Abstract Title: Orally-Administered Ustekinumab Biosimilar RT-111 Delivered Via a Robotic Pill Yields Bioavailability Comparable to Subcutaneous Injection in Canines
Session Type: Poster Session
Session Title: Animal Models of IBD: Pre-Clinical Treatment of Intestinal Inflammation
Session Date & Time: May 21, 2024 from 12:30 PM to 1:30 PM EDT
Presenting Author: Kyle Horlen, DVM
Abstracts selected by the American Gastroenterological Association (AGA) for presentation at DDW will be available in a supplement to Gastroenterology. The presentations and information about DDW 2024 may be accessed at https://ddw.org/.
About Digestive Disease Week
Digestive Disease Week® (DDW) is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. Jointly sponsored by the American Association for the Study of Liver Diseases (AASLD), the American Gastroenterological Association (AGA), the American Society for Gastrointestinal Endoscopy (ASGE) and the Society for Surgery of the Alimentary Tract (SSAT), DDW is an in-person and online meeting from May 18-21, 2024. The meeting showcases more than 4,400 abstracts and hundreds of lectures on the latest advances in GI research, medicine and technology. More information can be found at www.ddw.org.
About RaniPill® Capsule
Rani Therapeutics has developed a disruptive technology for the oral delivery of biologics. The RaniPill® Capsule is an innovative robotic pill that moves fully intact through the stomach, where acids typically break down drugs, and then reaches the intestine, where it delivers the drug via transenteric injection. The injection is painless, and the drug is rapidly absorbed.
RT-111 is an orally administered RaniPill® capsule containing an ustekinumab biosimilar, CT-P43, designed to offer a highly differentiated dosing regimen for patients with psoriasis and other chronic inflammatory diseases compared to both injectable biologics and oral small molecules and peptides.
About Rani Therapeutics
Rani Therapeutics is a clinical stage biotherapeutics company focused on advancing technologies to enable the development of orally administered biologics and drugs. Rani has developed the RaniPill® capsule, which is a novel, proprietary and patented platform technology, intended to replace subcutaneous injection or intravenous infusion of biologics and drugs with oral dosing. Rani has successfully conducted several preclinical and clinical studies to evaluate safety, tolerability and bioavailability using RaniPill® capsule technology. For more information, visit ranitherapeutics.com.

Frequently Asked Questions

What is Rani Therapeutics presenting at DDW 2024?

Rani Therapeutics will present data on the RaniPill® capsule at DDW 2024.

When is Rani Therapeutics' presentation at DDW?

The presentation is on May 19, 2024, from 3:00 PM to 3:15 PM EDT.

What is the RaniPill® capsule designed for?

The RaniPill® capsule enables the oral delivery of biologics, avoiding injections.

What is RT-111 in the context of Rani's research?

RT-111 is an ustekinumab biosimilar delivered via the RaniPill® capsule.

What is Digestive Disease Week (DDW)?

DDW is a major international conference on gastroenterology and related fields.

Last updated: May 9, 2024