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Rani Therapeutics to Present Preclinical Data on Oral Delivery of Semaglutide via the RaniPill® Capsule at ObesityWeek® 2025

Key Takeaway: Rani Therapeutics will present preclinical data on its RaniPill® capsule at ObesityWeek 2025. The study demonstrates that oral Semaglutide (RT-116) in dogs is bioequivalent to subcutaneous injections, producing similar weight loss results. The presentation will occur on November 6, 2025, in Atlanta, Georgia.
Price reaction · baseline $1.66 (2025-10-29 close) · hit pre-market · clean, no other RANI news in the window
day 0 close
-12.7%
day 1
+32.5%
day 3 · peak
+43.4%

Market Sentiment Analysis

POSITIVE FACTORS

  • Rani Therapeutics is advancing oral delivery technologies for biologics.
  • Presentation at ObesityWeek 2025 highlights innovative research.
  • Preclinical data shows oral Semaglutide is bioequivalent to injections.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Cash runway
~18 mo
Low dilution risk
Lead asset
Stelara
Phase 1 · Healthy Volunteers

Full Press Release Details

SAN JOSE, Calif., Oct. 30, 2025 (GLOBE NEWSWIRE) -- Rani Therapeutics Holdings, Inc. (“Rani Therapeutics” or “Rani”) (Nasdaq: RANI), a clinical-stage biotherapeutics company focused on the oral delivery of biologics and drugs, today announced that it will present preclinical data on the RaniPill® capsule, the company’s oral delivery platform, at ObesityWeek® 2025 taking place both virtually and in-person on November 4-7, 2025 in Atlanta, Georgia.
Details of the presentation are as follows:
Abstract Title:Oral Semaglutide (RT-116) in Dogs is Bioequivalent to SC Injections and Elicits Similar Weight LossSession Type:Poster SessionPoster Number:647Location:Georgia World Congress Center, Exhibit Hall A1Session Date & Time:November 6, 2025 from 2:30 pm – 3:30 pm E.T.Presenting Author:Kyle Horlen, DVM, VP of Nonclinical Development

About Rani Therapeutics

Rani Therapeutics is a clinical-stage biotherapeutics company focused on advancing technologies to enable the development of orally administered biologics and drugs. Rani has developed the RaniPill® capsule, which is a novel, proprietary and patented platform technology, intended to replace subcutaneous injection or intravenous infusion of biologics and drugs with oral dosing. Rani has successfully conducted several preclinical and clinical studies to evaluate safety, tolerability and bioavailability using RaniPill® capsule technology.

Frequently Asked Questions

What is the RaniPill® capsule?

The RaniPill® capsule is a proprietary platform technology for oral delivery of biologics.

When will Rani present its data?

Rani will present its preclinical data at ObesityWeek 2025 on November 6, 2025.

What does the preclinical data show?

The data indicates that oral Semaglutide is bioequivalent to subcutaneous injections.

Where is ObesityWeek 2025 held?

ObesityWeek 2025 will take place in Atlanta, Georgia.

Last updated: Oct 30, 2025