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Top U.S. Honor Roll Hospital Expands Use of INSPIRA ART100 System to Lung Transplant Procedures RA'ANANA, Israel

Key Takeaway: Inspira Technologies OXY B.H.N. Ltd. has announced that a leading U.S. hospital has expanded its use of the INSPIRA ART100 system to include lung transplantation procedures. This decision follows a positive experience with the ART100 in other clinical applications. The move is seen as strong validation of the system's performance and may pave the way for more widespread adoption in advanced respiratory care. Furthermore, this expansion reflects growing confidence in Inspira’s innovative technologies within the medical community.

Market Sentiment Analysis

POSITIVE FACTORS

  • Expansion into lung transplant procedures signifies confidence in the ART100 system.
  • The U.S. hospital is ranked among the nation's top 20, enhancing credibility.
  • Inspira Technologies is gaining recognition and market presence in advanced respiratory care.
  • Successful prior use of ART100 provided a basis for this expanded application.

Full Press Release Details

Top U.S. Honor Roll Hospital Expands Use of
INSPIRA ART100 System to Lung Transplant Procedures
Israel, September 2, 2025 -- Inspira Technologies OXY B.H.N. Ltd. (NASDAQ: IINN) ("Inspira," "Inspira
Technologies," or the "Company"), a pioneer in innovative life-support and diagnostic technologies, today
announced that a top U.S. hospital, has expanded its clinical use of the INSPIRA ART100 system to lung transplantation procedures,
one of the most demanding applications in advanced respiratory care. The hospital was included in the U.S. News & World Report 2025-2026
Best Hospitals Honor Roll of the nation's top 20 hospitals, and has multiple specialties consistently ranked among the top five
This clinical expansion follows the hospital's positive experience
with the ART100 system in prior clinical use. The decision by one of the nation's most highly ranked hospitals to extend the use
of Inspira's technology into such a critical and complex surgical procedure provides strong external validation of the system's
performance and clinical value. Expanding the application of the ART100 into lung transplantation highlights its potential as a reliable
platform for advanced respiratory support across multiple indications.
Chief Executive Officer of Inspira Technologies, stated: "The decision by one of the most decorated and respected medical institutions
in the United States
to broaden the use of our ART100 system into lung transplantation is a highly meaningful step for Inspira. It reflects the growing confidence
leading hospitals are placing in our technology and underscores its potential to become an essential platform in advanced respiratory
care. This expansion marks an important step toward establishing the ART100 as part of the standard of care in the most complex surgical
This U.S. clinical expansion follows Inspira's recently announced
multi-million dollar binding government orders for ART100 systems, underscoring the Company's growing global footprint and commercial
About Inspira Technologies
Inspira Technologies is a commercial-stage medical device company specializing
in advanced respiratory support and real-time blood monitoring solutions. The Company's U.S. Food and Drug Administration -cleared
INSPIRA ART100 system is approved for cardiopulmonary bypass in the U.S. and ECMO (Extracorporeal Membrane Oxygenation) procedures
outside the U.S and serves as a foundation for the development of the INSPIRA ART500, a next-generation system designed to deliver oxygenation
while patients remain awake and spontaneously breathing. Inspira Technologies is also advancing HYLA , a proprietary blood sensor
platform offering continuous, non-invasive monitoring. With multiple cleared products, a growing IP portfolio, and strategic streamlining
of its operations, Inspira Technologies is increasingly positioned as an attractive platform within the life-support and MedTech landscape.
The Company's recent internal shifts may reflect broader alignment with long-term industry trends, including consolidation, cross-sector
collaboration, and potential strategic partnerships. For more information, visit: https://inspira-technologies.com
Forward-Looking Statement Disclaimer
This press release contains express or implied forward-looking statements
pursuant to U.S. Federal securities laws. These forward-looking statements are based on the current expectations of the management of
the Company only and are subject to a number of factors and uncertainties that could cause actual results to differ materially from those
described in the forward-looking statements. For example, the Company is using forward-looking statements when it discusses the expanded
use of the ART100 by a leading U.S. hospital, particularly during lung transplant procedures, that the decision to expand the use of the
ART100 during such a complex surgical procedure provides strong external validation of the system's performance and an indication
of its clinical value, that expanding the application of the ART100 into lung transplantation highlights the ART100's potential
as a reliable platform for advanced respiratory support across multiple indications, that the expanded use of the ART100 reflects the
growing confidence leading hospitals are placing in its technology and underscores the ART100's potential to become an essential
platform in advanced respiratory care and that the expansion marks an important step toward establishing the ART100 as part of the standard
of care in the most complex surgical settings. These forward-looking statements and their implications are based solely on the current
expectations of the Company's management and are subject to a number of factors and uncertainties that could cause actual results to differ
materially from those described in the forward-looking statements. Except as otherwise required by law, the Company undertakes no obligation
to publicly release any revisions to these forward-looking statements to reflect events or circumstances after the date hereof or to reflect
the occurrence of unanticipated events. More detailed information about the risks and uncertainties affecting the Company is contained
under the heading "Risk Factors" in the Company's annual report on Form 20-F for the fiscal year ended December 31, 2024, filed
with the U.S. Securities and Exchange Commission (the "SEC"), which is available on the SEC's website at www.sec.gov.
Inspira Technologies - Media Relations
Phone: +972-9-9664485

Frequently Asked Questions

What recent application did the INSPIRA ART100 system expand to?

The INSPIRA ART100 system has expanded its use to lung transplantation procedures.

Which prestigious U.S. recognition did the hospital receive?

The hospital was listed in the U.S. News & World Report 2025-2026 Best Hospitals Honor Roll.

What does the CEO of Inspira Technologies say about the expansion?

The CEO noted that this expansion reflects growing confidence in their technology.

What markets does the INSPIRA ART100 serve?

The INSPIRA ART100 is cleared for cardiopulmonary bypass in the U.S. and ECMO outside.

What is Inspira Technologies also developing alongside the ART100?

Inspira Technologies is developing the INSPIRA ART500 for awake oxygenation.

Last updated: Sep 2, 2025