Full Press Release Details
Quoin Pharmaceuticals Provides Corporate Update
and Announces Second Quarter 2024 Financial Results
Quoin Broadens Product Portfolio through Research
Agreement with University College Cork, Ireland
Company Expands On-going Clinical Trials in
Netherton Syndrome to Include International Sites
Announced Plans to Initiate Clinical Study in
Peeling Skin Syndrome
Continues to Evaluate M&A Opportunities
in Rare and Orphan Diseases
ASHBURN, Va., August 8, 2024 -- Quoin Pharmaceuticals
Ltd. (NASDAQ: QNRX) (the "Company" or "Quoin"), a clinical stage, specialty pharmaceutical company focused on
developing and commercializing novel treatments for rare and orphan diseases, today provides a business update and announces financial
results for the three and six months ended June 30, 2024.
Quoin CEO, Dr. Michael Myers, said, "This was another quarter
of solid achievement and incremental progress for Quoin. Our research partnership with University College Cork, Ireland, has the potential
to lead to the development of a number of topical rapamycin (sirolimus) formulations utilizing the university's proprietary dissolvable
microneedles delivery technology. Quoin intends to clinically develop any successfully developed formulations as potential treatments
for several rare and orphan diseases. We continued to advance the clinical development of our lead product, QRX003, as a potential treatment
for Netherton Syndrome with the announcement of the international expansion of clinical trial sites. The first international site will
be opened in Saudi Arabia and Quoin has engaged an experienced Clinical Research Organization to manage all local activities. In addition,
we have also engaged a European based CRO as we seek to expand our clinical activities into several EU countries. All international sites
will operate under the auspices of Quoin's open Investigational New Drug application with the US Food and Drug Administration. Earlier
this week, we announced our plans to initiate a clinical study in Peeling Skin Syndrome, a rare genetic disease for which there are currently
no approved treatments or cures. The first clinical site and patient have been identified and we are working closely with the site to
initiate clinical testing as promptly as possible. Finally, throughout the quarter we continued to evaluate several promising M&A
opportunities in rare and orphan diseases. This remains a priority for Quoin throughout the remainder of 2024."
Recent Corporate Highlights -
Financial Highlights
About Quoin Pharmaceuticals Ltd.
Quoin Pharmaceuticals Ltd. is a clinical stage specialty pharmaceutical
company focused on developing and commercializing therapeutic products that treat rare and orphan diseases. We are committed to addressing
unmet medical needs for patients, their families, communities and care teams. Quoin's innovative pipeline comprises four products
in development that collectively have the potential to target a broad number of rare and orphan indications, including Netherton Syndrome,
Peeling Skin Syndrome, Palmoplantar Keratoderma, Scleroderma, Epidermolysis Bullosa and others. For more information, visit: www.quoinpharma.com or LinkedIn for
Cautionary Note Regarding Forward Looking Statements
cautions that statements in this press release that are not a description of historical facts are forward-looking statements within the
meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by the use of words referencing
future events or circumstances such as "expect," "intend," "plan," "anticipate," "believe,"
and "will," among others. All statements that reflect the Company's expectations, assumptions, projections, beliefs,
or opinions about the future, other than statements of historical fact, are forward-looking statements, including, without limitation,
statements relating to plans to initiate clinical study in peeling skin syndrome and the timing thereof, plans to evaluate M&A opportunities
in rare and orphan diseases, the partnership with the UCC potentially leading to the development of a number of topical rapamycin (sirolimus)
formulations utilizing the university's proprietary dissolvable microneedles delivery technology, the Company intends to clinically
develop any successfully developed formulations as potential treatments for several rare and orphan diseases, the opening of the Company's
first international site in Saudi Arabia, the Company seeking to expand its clinical activities into a number of EU countries. the Company's
expected cash runway, and Quoin's products in development collectively have the potential to target a broad number of rare and
orphan indications, including Netherton Syndrome, Peeling Skin Syndrome, Palmoplantar Keratoderma, Scleroderma, Epidermolysis Bullosa
and others. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed
or implied by such forward-looking statements. These forward-looking statements are based upon the Company's current expectations
and involve assumptions that may never materialize or may prove to be incorrect. Actual results and the timing of events could differ
materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties including, but not
limited to, the timing of the clinical studies may be delayed, the clinical studies may not generate the results anticipated, the partnership
with UCC may not lead to development of the formulations expected, the Company being unable to expand into a number of EU countries as
planned, the Company may need to raise additional funds sooner than planned, the clinical studies may not generate data which is sufficiently
robust and comprehensive to support an NDA filing and the Company's ability to obtain regulatory approvals. More detailed information
about the risks and uncertainties affecting the Company is summarized in the Company's Annual Report on Form 10-K for the year
ended December 31, 2023 and in other filings the Company has made and may make
with the SEC in the future. One should not place undue reliance on these forward-looking statements, which speak only as of the
date on which they were made. The Company undertakes no obligation to update such statements to reflect events that occur or circumstances
that exist after the date on which they were made, except as may be required by law.
For further information:
PHARMACEUTICALS, LTD.
| June 30, | December 31, | |||||||
| 2024 | 2023 | |||||||
| (Unaudited) | ||||||||
| ASSETS | ||||||||
| Current assets: | ||||||||
| Cash and cash equivalents | $ | 2,845,126 | $ | 2,401,198 | ||||
| Investments | 9,725,463 | 8,293,663 | ||||||
| Prepaid expenses and other current assets | 650,696 | 591,034 | ||||||
| Total current assets | 13,221,285 | 11,285,895 | ||||||
| Prepaid expenses - long term | 300,000 | 300,000 | ||||||
| Intangible assets, net | 533,334 | 583,334 | ||||||
| Total assets | $ | 14,054,619 | $ | 12,169,229 | ||||
| LIABILITIES AND SHAREHOLDERS' EQUITY | ||||||||
| Current liabilities: | ||||||||
| Accounts payable | $ | 819,674 | $ | 526,523 | ||||
| Accrued expenses | 1,386,625 | 1,308,706 | ||||||
| Accrued interest and financing expense | 1,146,251 | 1,146,251 | ||||||
| Due to officers - short term | 600,000 | 600,000 | ||||||
| Total current liabilities | 3,952,550 | 3,581,480 | ||||||
| Due to officers - long term | 2,623,733 | 2,923,733 | ||||||
| Total liabilities | $ | 6,576,283 | $ | 6,505,213 | ||||
| Commitments and contingencies | ||||||||
| Shareholders' equity: | ||||||||
| Ordinary shares, no par value per share, 100,000,000 ordinary shares authorized at | $ | - | $ | - | ||||
| June 30, 2024 and December 31, 2023, respectively - 3,979,970 (3,979,970 ADS's) ordinary shares issued and outstanding at June 30, 2024 and 987,220 (987,220 ADS's) at December 31, 2023 | ||||||||
| Additional paid in capital | 57,982,969 | 51,867,336 | ||||||
| Accumulated deficit | (50,504,633 | ) | (46,203,320 | ) | ||||
| Total shareholders' equity | 7,478,336 | 5,664,016 | ||||||
| Total liabilities and shareholders' equity | $ | 14,054,619 | $ | 12,169,229 |
PHARMACEUTICALS, LTD.
Statement of Operations (unaudited)
| Three months ended June 30, | Six months ended June 30, | |||||||||||||||
| 2024 | 2023 | 2024 | 2023 | |||||||||||||
| Operating expenses | ||||||||||||||||
| General and administrative | $ | 1,617,769 | $ | 1,634,960 | $ | 3,233,221 | $ | 3,318,777 | ||||||||
| Research and development | 519,349 | 625,104 | 1,362,181 | 1,716,837 | ||||||||||||
| Total operating expenses | 2,137,118 | 2,260,064 | 4,595,402 | 5,035,614 | ||||||||||||
| Other (income) and expenses | ||||||||||||||||
| Unrealized loss | 2,177 | 34,472 | 8,686 | 14,045 | ||||||||||||
| Realized and accrued interest income | (165,262 | ) | (187,589 | ) | (302,775 | ) | (339,643 | ) | ||||||||
| Total other income | (163,085 | ) | (153,117 | ) | (294,089 | ) | (325,598 | ) | ||||||||
| Net loss | $ | (1,974,033 | ) | $ | (2,106,947 | ) | $ | (4,301,313 | ) | $ | (4,710,016 | ) | ||||
| Loss per ADS | ||||||||||||||||
| Loss per ADS | ||||||||||||||||
| Basic | $ | (0.39 | ) | $ | (2.13 | ) | $ | (1.20 | ) | $ | (5.79 | ) | ||||
| Fully-diluted | $ | (0.39 | ) | $ | (2.13 | ) | $ | (1.20 | ) | $ | (5.79 | ) | ||||
| Weighted average number of ADS's outstanding | ||||||||||||||||
| Basic | 5,049,720 | 987,220 | 3,576,506 | 813,187 | ||||||||||||
| Fully-diluted | 5,049,720 | 987,220 | 3,576,506 | 813,187 |