Announces a Major Technological Breakthrough for

Announces a Major Technological Breakthrough for

Industrialization of Apotainer Stem Cell Product Line

first in kind (patent pending) technology of FasL-magnetic beads

significantly improve the stem cells selection process

beads are used within Cellect's ApoTainer and designed to allow replacement of complex

laboratory procedures significantly

reducing time and costs while increasing efficacy

Shai Yarkoni, Cellect CEO commented: "We believe the development for industrialization of

Apotainer represents a breakthrough in meeting the rapidly growing demand for stem cells as a raw material."

Aviv, Israel - October 22, 2018 - Cellect Biotechnology Ltd. (Nasdaq: APOP), a developer of a novel stem cell

isolation technology, announced that it has successfully developed for industrialization its first in kind new technology as an

integral part of Cellect's ApoTainer . The new technology utilizes FasL-coated magnetic beads for maximizing efficacy

and scalability of stem cell-based products' manufacturing. The Apotainer improves the uniformity and hence quality

of the outcome thereby supporting the safety and efficacy of raw material for all cell therapy.

the last 6 months, the Cellect team was able to optimize the beads size, coating technology, elimination of the release of FasL

into the medium, all while preserving the biological activity observed in Cellect's ongoing human clinical trial. As previously

reported, pre-clinical proof of concept testing of the ApoTainer has shown that the use of FasL-coated magnetic

beads significantly increases the active surface allowing a dramatic increase of interactions between the selecting agent and

the cells. Further, such testing showed that the outcome increases specific elimination of certain (but not all) of the non-stem

cells while full preservation of the number and function of the stem and progenitor cells.

enhancement of the ApoTainer with the Fas-L-presenting magnetic beads is designed to replace highly complex and expensive

procedures currently used by laboratories (e.g. T cells depletion), with a significantly more effective process at a fraction

of the time and cost.

the ApoTainer , Cellect expects blood stem cell donation to be transplantable within less than 6 hours from donation through

a simple process performed bedside instead of undergoing a lengthy laboratory procedure in a highly specialized setting. The standard

medical procedure for reaching enriched stem cells currently costs tens of thousands of dollars and produces significant adverse

About Cellect Biotechnology Ltd.

Biotechnology (NASDAQ: APOP) has developed a breakthrough technology for the selection of stem cells from any given tissue that

aims to improve a variety of stem cell-based therapies.

Company's technology is expected to provide research, hospitals and pharma companies with the tools to rapidly isolate stem cells

in quantity and quality allowing stem cell-based treatments and procedures in a wide variety of applications in regenerative medicine.

The Company's current clinical trial is aimed at bone marrow transplantations in cancer treatment.

press release contains forward-looking statements about the Company's expectations, beliefs and intentions. Forward-looking statements

can be identified by the use of forward-looking words such as "believe", "expect", "intend", "plan",

"may", "should", "could", "might", "seek", "target", "will",

"project", "forecast", "continue" or "anticipate" or their negatives or variations of

these words or other comparable words or by the fact that these statements do not relate strictly to historical matters. For example,

forward-looking statements are used in this press release when we discuss the future potential of the Apotainer. These forward-looking

statements and their implications are based on the current expectations of the management of the Company only and are subject

to a number of factors and uncertainties that could cause actual results to differ materially from those described in the forward-looking

statements. In addition, historical results or conclusions from scientific research and clinical studies do not guarantee that

future results would suggest similar conclusions or that historical results referred to herein would be interpreted similarly

in light of additional research or otherwise. The following factors, among others, could cause actual results to differ materially

from those described in the forward-looking statements: the Company's history of losses and needs for additional capital to fund

its operations and its inability to obtain additional capital on acceptable terms, or at all; the Company's ability to continue

as a going concern; uncertainties of cash flows and inability to meet working capital needs; the Company's ability to obtain regulatory

approvals; the Company's ability to obtain favorable pre-clinical and clinical trial results; the Company's technology may not

be validated and its methods may not be accepted by the scientific community; difficulties enrolling patients in the Company's

clinical trials; the ability to timely source adequate supply of FasL; risks resulting from unforeseen side effects; the Company's

ability to establish and maintain strategic partnerships and other corporate collaborations; the scope of protection the Company

is able to establish and maintain for intellectual property rights and its ability to operate its business without infringing

the intellectual property rights of others; competitive companies, technologies and the Company's industry; unforeseen scientific

difficulties may develop with the Company's technology; and the Company's ability to retain or attract key employees whose knowledge

is essential to the development of its products. Any forward-looking statement in this press release speaks only as of the date

of this press release. The Company undertakes no obligation to publicly update or review any forward-looking statement, whether

as a result of new information, future developments or otherwise, except as may be required by any applicable securities laws.

More detailed information about the risks and uncertainties affecting the Company is contained under the heading "Risk Factors"

in the Company's Annual Report on Form 20-F for the fiscal year ended December 31, 2017 filed with the U.S. Securities and Exchange

Commission ("SEC"), which is available on the SEC's website, http://www.sec.gov, and in the Company's periodic filings

Leibovitz, Chief Financial Officer