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PolyPid to Host Conference Call and Webcast to Discuss D-PLEX₁₀₀ SHIELD II Phase 3 Trial Topline Results on Monday, June 9, 2025

Key Takeaway: PolyPid Ltd. will host a conference call and webcast on June 9, 2025, to discuss topline results from its SHIELD II Phase 3 trial of D-PLEX100. This trial aims to evaluate the efficacy of D-PLEX100 in preventing surgical site infections among patients undergoing abdominal colorectal surgery. The company's proprietary PLEX technology is designed to optimize drug delivery, enhancing surgical recovery. PolyPid is also exploring other therapeutic possibilities for solid tumors, starting with glioblastoma.
Price reaction · baseline $3.16 (2025-06-05 close) · hit after-hours · 1 other PYPD headline(s) in the window, move may be shared
day 0 close
+3.5%

Market Sentiment Analysis

POSITIVE FACTORS

  • PolyPid is set to report topline data for its Phase 3 trial on D-PLEX100.
  • The company focuses on improving surgical outcomes, indicating a strong therapeutic intent.
  • D-PLEX100 could potentially reduce surgical site infections for colorectal surgery patients.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+50%
120-day peak, hindsight
Typical move
4.8%
average across 4 past catalysts
Lead asset
D-PLEX
Phase 3 · Surgical Site Infection

Full Press Release Details

PETACH TIKVA, Israel, June 06, 2025 (GLOBE NEWSWIRE) -- PolyPid Ltd. (Nasdaq: PYPD), (“PolyPid” or the “Company”), a late-stage biopharma company aiming to improve surgical outcomes, today announced that it will host a conference call and webcast to report topline data for the SHIELD II Phase 3 trial, evaluating D-PLEX100 for the prevention of surgical site infections in patients undergoing abdominal colorectal surgery, on Monday, June 9, at 8:30 a.m. ET.
To ensure you are connected prior to the beginning of the call, PolyPid suggests registering a minimum of 5 minutes before the start of the call.
Conference Call Dial-In & Webcast Information:
Date: Monday, June 9, 2025
Time: 8:30 AM Eastern Time
Conference Call: https://register-conf.media-server.com/register/BIb5bb85aa1ffc4940b78f7191b278ca77
Webcast: https://edge.media-server.com/mmc/p/k6n5hrft
PolyPid Ltd. (Nasdaq: PYPD) is a late-stage biopharma company aiming to improve surgical outcomes. Through locally administered, controlled, prolonged-release therapeutics, PolyPid’s proprietary PLEX (Polymer-Lipid Encapsulation matriX) technology pairs with Active Pharmaceutical Ingredients (APIs), enabling precise delivery of drugs at optimal release rates over durations ranging from several days to months. PolyPid’s lead product candidate D-PLEX100 is in Phase 3 clinical trial for the prevention of abdominal colorectal surgical site infections. In addition, the Company is currently in preclinical stages to test the efficacy of OncoPLEX for the treatment of solid tumors, beginning with glioblastoma.

Frequently Asked Questions

When will PolyPid report SHIELD II trial data?

PolyPid will report SHIELD II trial data on June 9, 2025, at 8:30 AM ET.

What is D-PLEX100 used for?

D-PLEX100 aims to prevent surgical site infections in abdominal colorectal surgery.

How can I join the conference call?

Register at least 5 minutes before the call using the provided conference link.

What technology does PolyPid use for drug delivery?

PolyPid uses PLEX technology for controlled, prolonged-release therapeutics.

Is PolyPid developing treatments for tumors?

Yes, PolyPid is testing OncoPLEX for solid tumors, starting with glioblastoma.

Last updated: Jun 6, 2025