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PolyPid to Report Fourth Quarter 2025 Financial Results and Operational Highlights on February 11, 2026

Key Takeaway: PolyPid Ltd. will announce its fourth quarter 2025 financial results and operational highlights on February 11, 2026. The company will host a conference call at 8:30 AM ET to discuss these results. PolyPid is advancing its lead product candidate, D-PLEX100, for preventing surgical site infections, with an NDA submission expected in early 2026.
Price reaction · baseline $4.8 (2026-01-27 close) · hit pre-market · 1 other PYPD headline(s) in the window, move may be shared
day 0 close
-1.7%

Market Sentiment Analysis

POSITIVE FACTORS

  • PolyPid is set to report Q4 2025 results, indicating ongoing business activity.
  • The company is advancing its lead product candidate, D-PLEX100, towards NDA submission.
  • Positive phase 3 results suggest potential success in preventing surgical site infections.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+50%
120-day peak, hindsight
Typical move
4.8%
average across 4 past catalysts
Lead asset
D-PLEX
Phase 3 · Surgical Site Infection

Full Press Release Details

PETACH TIKVA, Israel, Jan. 28, 2026 (GLOBE NEWSWIRE) -- PolyPid Ltd. (Nasdaq: PYPD) ("PolyPid" or the "Company"), a late-stage biopharma company aiming to improve surgical outcomes, today announced that it will report its fourth quarter 2025 financial results and operational highlights before the open of the U.S. financial markets on Wednesday, February 11, 2026. The Company will host a conference call and webcast at 8:30 AM Eastern Time to discuss the results and provide an update on business operations.
To ensure you are connected prior to the beginning of the call, PolyPid suggests registering a minimum of 5 minutes before the start of the call. For those not planning to ask a question of management, the Company recommends listening via the webcast.

Conference Call Dial-In & Webcast Information:

Date: February 11, 2026
Time: 8:30 AM Eastern Time
Conference Call: https://register-conf.media-server.com/register/BI793c5305462d49cea4ba91529d2636bf
Webcast: https://edge.media-server.com/mmc/p/izp7gdk6
About PolyPidPolyPid Ltd. (Nasdaq:PYPD) is a late-stage biopharma company aiming to improve surgical outcomes. Through locally administered, controlled, prolonged-release therapeutics, PolyPid’s proprietary PLEX (Polymer-Lipid Encapsulation matriX) technology pairs with Active Pharmaceutical Ingredients (APIs), enabling precise delivery of drugs at optimal release rates over durations ranging from several days to months. Following positive phase 3 results, New Drug Application (NDA) submission of D-PLEX100, PolyPid’s lead product candidate, for the prevention of abdominal colorectal surgical site infections, is expected in early 2026. In addition, the Company has an innovative pipeline in oncology, obesity and diabetes.
For additional Company information, please visithttp://www.polypid.comand follow us onTwitter (X)and LinkedIn.
Forward-looking StatementsThis press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act and other securities laws. Words such as “expects,” “anticipates,” “intends,” “plans,” “believes,” “seeks,” “estimates” and similar expressions or variations of such words are intended to identify forward-looking statements. For example, the Company is using forward-looking statements when it discusses the NDA submission of D-PLEX100and the timing thereof. Forward-looking statements are not historical facts, and are based upon management’s current expectations, beliefs and projections, many of which, by their nature, are inherently uncertain. Such expectations, beliefs and projections are expressed in good faith. However, there can be no assurance that management’s expectations, beliefs and projections will be achieved, and actual results may differ materially from what is expressed in or indicated by the forward-looking statements. Forward-looking statements are subject to risks and uncertainties that could cause actual performance or results to differ materially from those expressed in the forward-looking statements. For a more detailed description of the risks and uncertainties affecting the Company, reference is made to the Company’s reports filed from time to time with the Securities and Exchange Commission, including, but not limited to, the risks detailed in the Company’s Annual Report on Form 20-F filed on February 26, 2025. Forward-looking statements speak only as of the date the statements are made. The Company assumes no obligation to update forward-looking statements to reflect actual results, subsequent events or circumstances, changes in assumptions or changes in other factors affecting forward-looking information except to the extent required by applicable securities laws. If the Company does update one or more forward-looking statements, no inference should be drawn that the Company will make additional updates with respect thereto or with respect to other forward-looking statements.
References and links to websites have been provided as a convenience, and the information contained on such websites is not incorporated by reference into this press release. PolyPid is not responsible for the contents of third-party websites.

Company Contact:PolyPid Ltd.Ori Warshavsky908-858-5995IR@Polypid.com

Investor Relations Contact:Arx Investor RelationsNorth American Equities Deskpolypid@arxhq.com

Frequently Asked Questions

When will PolyPid report its Q4 2025 results?

PolyPid will report its Q4 2025 financial results on February 11, 2026.

What is the purpose of the conference call?

The conference call will discuss the financial results and provide business updates.

What is D-PLEX100?

D-PLEX100 is PolyPid's lead product candidate aimed at preventing surgical site infections.

When is the NDA submission for D-PLEX100 expected?

The NDA submission for D-PLEX100 is expected in early 2026.

Last updated: Jan 28, 2026