PolyPid Announces Reverse Share Split

Announces Reverse Share Split

TIKVA, Israel, September 20, 2023 -- PolyPid Ltd. (Nasdaq: PYPD) ("PolyPid" or the "Company"), a late-stage

biopharma company aiming to improve surgical outcomes, today announces a reverse share split (the "Reverse Split") of the

Company's issued and outstanding ordinary shares, no par value ("Ordinary Shares"), at the ratio of 1-for-30, such

that each thirty (30) Ordinary Shares, shall be consolidated into one (1) Ordinary Share.

Company obtained shareholders' approval for the Reverse Split at a ratio of between 1:10 and 1:30 at an extraordinary general meeting

of shareholders, which took place on September 18, 2023. The Company's board of directors then approved the Reverse Split ratio

of 1-for-30 on September 18, 2023.

first date when the Company's Ordinary Shares will begin trading on the Nasdaq Capital Market ("Nasdaq") on a post-

reverse split basis is expected to be Thursday, September 21, 2023. The Company's Ordinary Shares will continue to trade on the

Nasdaq under the symbol "PYPD" and the Company expects that the reverse share split will allow the Company to regain compliance

with Nasdaq's $1.00 minimum bid price requirement.

fractional Ordinary Shares will be issued as a result of the Reverse Split. In accordance with the Company's articles of association,

as currently in effect, all fractional shares shall be rounded to the nearest whole Ordinary Share, such that only shareholders holding

fractional consolidated shares of more than one half of one whole share shall be entitled to receive one consolidated share. In addition,

a proportionate adjustment will be made to the per share exercise price and the number of shares issuable upon the exercise of all outstanding

options or warrants entitling the holders to purchase Ordinary Shares.

Ltd. (Nasdaq: PYPD) is a late-stage biopharma company aiming to improve surgical outcomes. Through locally administered, controlled,

prolonged-release therapeutics, PolyPid's proprietary PLEX (Polymer-Lipid Encapsulation matriX) technology pairs with Active Pharmaceutical

Ingredients (APIs), enabling precise delivery of drugs at optimal release rates over durations ranging from several days to months. PolyPid's

lead product candidate D-PLEX100 is in Phase 3 clinical trial for the prevention of abdominal colorectal surgical site

infections. In addition, the Company is currently in preclinical stages to test the efficacy of OncoPLEX for the treatment of solid tumors,

beginning with glioblastoma.

press release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act and

other securities laws. Words such as "expects," "anticipates," "intends," "plans," "believes,"

"seeks," "estimates" and similar expressions or variations of such words are intended to identify forward-looking

statements. For example, the Company is using forward-looking statements when it discusses the timing of the reverse share split and

its expectation that the reverse share split will help the Company regain compliance with Nasdaq's $1.00 minimum bid price requirement.

Forward-looking statements are not historical facts, and are based upon management's current expectations, beliefs and projections,

many of which, by their nature, are inherently uncertain. Such expectations, beliefs and projections are expressed in good faith. However,

there can be no assurance that management's expectations, beliefs or projections will be achieved, and actual results may differ

materially from what is expressed in, or indicated by, the forward-looking statements. Forward-looking statements are subject to risks

and uncertainties that could cause actual performance or results to differ materially from those expressed in the forward-looking statements.

For a more detailed description of the risks and uncertainties affecting the Company, reference is made to the Company's reports

filed from time to time with the SEC, including, but not limited to, the risks detailed in the Company's Annual Report on Form

20-F filed on March 31, 2023. Forward-looking statements speak only as of the date the statements are made. The Company assumes no obligation

to update forward-looking statements to reflect actual results, subsequent events or circumstances, changes in assumptions or changes

in other factors affecting forward-looking information except to the extent required by applicable securities laws. If the Company does

update one or more forward-looking statements, no inference should be drawn that the Company will make additional updates with respect

thereto or with respect to other forward-looking statements.

and links to websites have been provided as a convenience, and the information contained on such websites is not incorporated by reference

into this press release. PolyPid is not responsible for the contents of third-party websites.