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PROQR THERAPEUTICS N.V. Index to Unaudited Condensed Consolidated Financial Statements PAGE Unaudited Condensed Consolidated Statement of Financial Position at

Key Takeaway: PROQR THERAPEUTICS N.V. Index to Unaudited Condensed Consolidated Financial Statements PAGE Unaudited Condensed Consolidated Statement of Financial Position at December 31, 2016 and December 31, 2015 1 Unaudited Condensed Consolidated Statement of Comprehensive Loss for

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PROQR THERAPEUTICS N.V.
Index to Unaudited Condensed Consolidated
Financial Statements
PAGE
Unaudited Condensed Consolidated Statement of Financial Position at December 31, 2016 and December 31, 2015 1
Unaudited Condensed Consolidated Statement of Comprehensive Loss for the Years and Three Month Periods ended December 31, 2016 and 2015 2
Unaudited Condensed Consolidated Statement of Changes in Equity for the Years ended December 31, 2016 and 2015 3
Unaudited Condensed Consolidated Statement of Cash Flows for the Years and Three Month Periods ended December 31, 2016 and 2015 4
Notes to Unaudited Condensed Consolidated Financial Statements 5
Unaudited Condensed Consolidated Financial Statements
PROQR THERAPEUTICS N.V.
Unaudited Condensed Consolidated Statement of Financial Position
December 31, 2016 December 31, 2015
1,000 1,000
Assets
Current assets
Cash and cash equivalents 59,200 94,865
Prepayments and other receivables 2,420 1,948
Social securities and other taxes 395 956
Total current assets 62,015 97,769
Property, plant and equipment 3,438 2,199
Intangible assets 90 141
Total assets 65,543 100,109
Liabilities and shareholders equity
Current liabilities
Finance lease liabilities -- 15
Trade payables 328 885
Social securities and other taxes 312 235
Pension premiums 13 16
Deferred income -- 144
Other current liabilities 6,057 4,191
Total current liabilities 6,710 5,486
Borrowings 5,697 4,824
Total liabilities 12,407 10,310
Shareholders equity
Shareholders equity 53,136 89,799
Total liabilities and shareholders equity 65,543 100,109
The notes are an integral part of these condensed consolidated financial statements.
THERAPEUTICS | ZERNIKEDREEF 9 | 2333 CK LEIDEN | THE NETHERLANDS | +31 88 166 7000 | WWW.PROQR.COM
Unaudited Condensed Consolidated Financial Statements
PROQR THERAPEUTICS N.V.
Unaudited Condensed Consolidated Statement of Profit or Loss and OCI
( in thousands, except share and per share data)
Three month period ended December 31, Year ended December 31,
2016 2015 2016 2015
1,000 1,000 1,000 1,000
Other income 103 958 1,828 3,235
Research and development costs (8,100 ) (6,494 ) (31,923 ) (23,401 )
General and administrative costs (2,260 ) (1,999 ) (9,478 ) (6,837 )
Total operating costs (10,360 ) (8,493 ) (41,401 ) (30,238 )
Operating result (10,257 ) (7,535 ) (39,573 ) (27,003 )
Finance income and expense 1,438 1,409 470 6,171
Result before corporate income taxes (8,819 ) (6,126 ) (39,103 ) (20,832 )
Income taxes
Net loss attributable to equity holders of the Company (8,819 ) (6,126 ) (39,103 ) (20,832 )
Other comprehensive income (16 ) 1 (16 ) 1
Total comprehensive loss (attributable to equity holders of the Company) (8,835 ) (6,125 ) (39,119 ) (20,831 )
Share information
Weighted average number of shares outstanding 1 23,346,856 23,345,860 23,346,507 23,343,262
Earnings per share attributable to the equity holders of the Company (expressed in Euro per share)
Basic loss per share 1 (0.38 ) (0.26 ) (1.68 ) (0.89 )
Diluted loss per share 1 (0.38 ) (0.26 ) (1.68 ) (0.89 )
The notes are an integral part of these condensed consolidated financial statements.
THERAPEUTICS | ZERNIKEDREEF 9 | 2333 CK LEIDEN | THE NETHERLANDS | +31 88 166 7000 | WWW.PROQR.COM
Unaudited Condensed Consolidated Financial Statements
PROQR THERAPEUTICS N.V.
Unaudited Condensed Consolidated Statement of Changes in Equity
Number of shares Total Share Capital Share Premium Equity Settled Employee Benefit Reserve Translation Reserve Accumulated Deficit Total Equity
1,000 1,000 1,000 1,000 1,000 1,000
Balance at January 1, 2015 23,338,154 934 123,581 687 -- (15,798 ) 109,404
Net loss -- -- -- -- -- (20,832 ) (20,832 )
Other comprehensive income -- -- -- -- 1 -- 1
Recognition of share-based payments -- -- -- 1,212 -- -- 1,212
Share options exercised 7,811 0 14 -- -- -- 14
Balance at December 31, 2015 23,345,965 934 123,595 1,899 1 (36,630 ) 89,799
Net loss -- -- -- -- -- (39,103 ) (39,103 )
Other comprehensive income -- -- -- -- (16 ) -- (16 )
Recognition of share-based payments -- -- -- 2,454 -- -- 2,454
Share options exercised 891 0 2 -- -- -- 2
Balance at December 31, 2016 23,346,856 934 123,597 4,353 (15 ) (75,733 ) 53,136
The notes are an integral part of these condensed consolidated financial statements.
THERAPEUTICS | ZERNIKEDREEF 9 | 2333 CK LEIDEN | THE NETHERLANDS | +31 88 166 7000 | WWW.PROQR.COM
Unaudited Condensed Consolidated Financial Statements
PROQR THERAPEUTICS N.V.
Unaudited Condensed Consolidated Statement of Cash Flows
Three month period ended December 31, Year ended December 31,
2016 2015 2016 2015
1,000 1,000 1,000 1,000
Cash flows from operating activities
Net result (8,835 ) (6,125 ) (39,119 ) (20,831 )
Adjustments for:
Depreciation 267 142 1,245 480
Share-based compensation 537 293 2,454 1,212
Financial income and expenses (1,438 ) (1,409 ) (470 ) (6,171 )
Changes in working capital 1,984 165 1,433 637
Cash used in operations (7,485 ) (6,934 ) (34,457 ) (24,673 )
Corporate income tax paid -- -- -- --
Interest received/(paid) 159 160 236 441
Net cash used in operating activities (7,326 ) (6,774 ) (34,221 ) (24,232 )
Cash flow from investing activities
Purchases of intangible assets -- -- -- (28 )
Purchases of property, plant and equipment (44 ) (203 ) (2,539 ) (1,296 )
Net cash used in investing activities (44 ) (203 ) (2,539 ) (1,324 )
Cash flow from financing activities
Proceeds from exercise of share options -- 0 2 14
Proceeds from borrowings 177 386 370 1,640
Redemption of financial lease -- (7 ) (15 ) (34 )
Net cash generated by financing activities 177 379 357 1,620
Net increase/(decrease) in cash and cash equivalents (7,193 ) (6,598 ) (36,403 ) (23,936 )
Currency effect cash and cash equivalents 1,472 1,451 738 6,065
Cash and cash equivalents, at beginning of the period 64,921 100,012 94,865 112,736
Cash and cash equivalents at the end of the period 59,200 94,865 59,200 94,865
The notes are an integral part of these condensed consolidated financial statements.
THERAPEUTICS | ZERNIKEDREEF 9 | 2333 CK LEIDEN | THE NETHERLANDS | +31 88 166 7000 | WWW.PROQR.COM
Unaudited Condensed Consolidated Financial Statements
PROQR THERAPEUTICS N.V.
Notes to Unaudited Condensed Consolidated Financial Statements
ProQR Therapeutics N.V., or ProQR or the Company , is a development stage company that primarily focuses on the development
and commercialization of novel therapeutic medicines.
Since September 18, 2014, the Company s ordinary shares are listed on the NASDAQ Global Market under
The Company was incorporated in the Netherlands, on February 21, 2012 and has been reorganized from a private company with limited
liability to a public company with limited liability on September 23, 2014. The Company has its statutory seat in Leiden, the Netherlands. The address of its headquarters and registered office is Zernikedreef 9, 2333 CK Leiden, the Netherlands.
ProQR Therapeutics N.V. is the ultimate parent company of the following entities:
As used in these condensed consolidated financial statements, unless the context
indicates otherwise, all references to ProQR or the Company refer to ProQR Therapeutics N.V. including its subsidiaries.
These condensed consolidated financial statements have been prepared in accordance with International Financial Reporting Standards
( IFRS ), as issued by the International Accounting Standards Board ( IASB ), in particular IAS 34 - Interim Financial Reporting. Certain information and disclosures normally included in financial statements prepared in
accordance with IFRS have been condensed or omitted. Accordingly, these condensed consolidated financial statements should be read in conjunction with the Company s annual financial statements for the year ended December 31, 2015. In the
opinion of management, all adjustments, consisting of normal recurring nature, considered necessary for a fair presentation have been included in the condensed consolidated financial statements.
The Company s financial results have varied substantially, and are expected to continue to vary, from period to period. The Company believes that its ordinary
activities are not linked to any particular seasonal factors.
The Company operates in one reportable segment, which comprises the discovery and development of
innovative, RNA based therapeutics.
THERAPEUTICS | ZERNIKEDREEF 9 | 2333 CK LEIDEN | THE NETHERLANDS | +31 88 166 7000 | WWW.PROQR.COM
Unaudited Condensed Consolidated Financial Statements
3. Adoption of new and revised International Financial Reporting Standards
The accounting policies adopted in the preparation of the condensed consolidated financial statements are consistent with those applied in the preparation of the
Company s annual financial statements for the year ended December 31, 2015. New Standards and Interpretations, which became effective as of January 1, 2016, did not have a material impact on our condensed consolidated financial
4. Critical Accounting Estimates and Judgments
application of the Company s accounting policies, management is required to make judgments, estimates and assumptions about the carrying amounts of assets and liabilities that are not readily apparent from other sources. The estimates and
associated assumptions are based on historical experience and other factors that are considered to be relevant. Actual results may differ from these estimates.
estimates and underlying assumptions are reviewed on an ongoing basis. Revisions to accounting estimates are recognized in the period in which the estimate is revised if the revision affects only that period or in the period of the revision and
future periods if the revision affects both current and future periods.
(a) Share-based payments
Share options granted to employees and consultants are measured at the fair value of the equity instruments granted. Fair value is determined through the use of the
Black-Scholes option-pricing model, which is considered the most appropriate model for this purpose by management.
Initially, the Company s ordinary shares
were not publicly traded and consequently the Company needed to estimate the fair value of its share and the expected volatility of that value. Please refer to the Company s annual financial statements for the year ended December 31, 2015
for the assumptions used in those estimates. The value of the underlying shares was determined on the basis of the prior sale of company stock method. As such, the Company has benchmarked the value per share to external transactions of Company
shares and external financing rounds.
For options granted from the moment of listing, the Company uses the closing price of the ordinary shares on the previous
business day as exercise price of the options granted.
The result of the share option valuations and the related compensation expense is dependent on the model and
input parameters used. Even though Management considers the fair values reasonable and defensible based on the methodologies applied and the information available, others might derive a different fair value for the Company s share options.
(b) Corporate income taxes
The Company recognizes deferred tax assets arising
from unused tax losses or tax credits only to the extent that the Company has sufficient taxable temporary differences or there is convincing evidence that sufficient taxable profit will be available against which the unused tax losses or unused tax
credits can be utilized. Management s judgment is that such convincing evidence is currently not sufficiently available and a deferred tax asset is therefore only recognized to the extent that the Company has sufficient taxable temporary
Grants (to be) received are reflected in
the balance sheet as other receivables or deferred income. At each balance sheet date, for grants approved, the Company estimates the associated costs incurred, the level of service performed and the progress of the associated projects. Based on
this analysis grant income is recognized.
THERAPEUTICS | ZERNIKEDREEF 9 | 2333 CK LEIDEN | THE NETHERLANDS | +31 88 166 7000 | WWW.PROQR.COM
Unaudited Condensed Consolidated Financial Statements
(d) Research and development expenditures
Research expenditures are currently not capitalized but are reflected in the income statement because the criteria for capitalization are not met. At each balance sheet
date, the Company estimates the level of service performed by the vendors and the associated costs incurred for the services performed.
Although we do not expect
the estimates to be materially different from amounts actually incurred, the understanding of the status and timing of services performed relative to the actual status and timing of services performed may vary and could result in reporting amounts
that are too high or too low in any particular period.
The condensed consolidated financial statements do not include all disclosures for critical accounting
estimates and judgments that are required in the annual consolidated financial statements and should be read in conjunction with the Company s annual financial statements for the year ended December 31, 2015.
5. Cash and Cash Equivalents
At December 31, 2016, the Company s
cash and equivalents were 59,200,000 as compared to 94,865,000 at December 31, 2015. A significant portion of the cash balance is
denominated in US dollars. The cash balances are held at banks with investment grade credit ratings. The cash at banks is at full disposal of the Company.
At December 31, 2016 and December 31, 2015, the other current liabilities consisted principally of accruals for services provided
by vendors not yet billed and other miscellaneous liabilities. The accrued liabilities as at December 31, 2016 increased compared to December 31, 2015 as a result of the increased level of research and development activities.
December 31, 2016 December 31, 2015
1,000 1,000
Innovation credit 4,598 4,228
Accrued interest on innovation credit 1,099 596
Total borrowings 5,697 4,824
Innovation credit ( Innovatiekrediet )
On June 1, 2012, ProQR was awarded an Innovation credit by the Dutch government, through its agency RVO (previously: AgentschapNL ) of the Ministry of
Economic Affairs, for the Company s cystic fibrosis program. The credit was increased in the course of 2013 through 2016. The credit covers 35% of the costs incurred in respect of the program up to an initial maximum of 5.0 million through March 31, 2018.
The credit is interest-bearing at a rate of 10% per annum. The
credit, including accrued interest, is repayable in three instalments on November 30, 2018, November 30, 2019 and November 30, 2020, depending on the technical success of the program.
The assets which are co-financed with the granted innovation credit are subject to a right of pledge for the benefit of RVO.
THERAPEUTICS | ZERNIKEDREEF 9 | 2333 CK LEIDEN | THE NETHERLANDS | +31 88 166 7000 | WWW.PROQR.COM
Last updated: Feb 28, 2017