Prenetics Acquires ACT Genomics, Creating a Leader in Comprehensive Cancer Genetics and Precision Oncology - Acquisition to bring germline and somatic testing, cell-free DNA-based (liquid biopsy), and tissue-genomic prof

Prenetics Acquires ACT Genomics, Creating a Leader in Comprehensive Cancer Genetics and Precision Oncology

LONDON AND HONG KONG, December 16, 2022 Prenetics Global Limited (NASDAQ: PRE), a leader in genomic and diagnostic testing,

today announced that it is acquiring a majority stake in ACT Genomics Holdings Company Limited ( ACT ), an Asia based genomics company specializing in precision oncology with operations in Hong Kong, Taiwan, Japan, Singapore, Thailand and

With the addition of ACT s technologies, capabilities and team, Prenetics will be well-positioned to accelerate the utilization of

genetic information throughout a cancer patient s journey. Starting from risk profiling and diagnostic testing, moving to therapy optimization, monitoring and recurrence surveillance, Prenetics will be able to deliver the information needed to

enable best-in-class personalized cancer care, said Danny Yeung Co-founder and Chief Executive Officer of Prenetics.

Every year in Asia, there are 9 million+ cancer patients with limited options, it is our goal to democratize testing and make cancer genomics accessible to all. Lastly, we are actively in close discussions on additional M&A opportunities

as we still have more than US$230 million+ in cash and receivables on our balance sheet.

In connection with the acquisition, Prof. Tony Mok will be

appointed to Prenetics Scientific Advisory Board, effective January 1, 2023. Prof. Mok currently serves as Chair Professor of the Department of Clinical Oncology of Chinese University of Hong Kong, is a

non-executive director of AstraZeneca plc (AZN LON), and an independent director of HUTCHMED (China) Limited (Nasdaq/AIM: HCM; HKEX:13).

We are very pleased to join forces with Prenetics, a company and team with which we have a shared vision to revolutionize and promote cancer molecular

diagnostics in Asia. said Prof. Tony Mok, Chairman of the Board, of ACT. ACT has achieved breakthrough success since its founding in 2014, and had joined forces with Sanomics since 2021 in pioneering and promoting precision medicine

cancer treatment management. Our flagship ACTOnco+ has provided oncologists and cancer patients with valuable biomarker information for therapy selection. This transaction provides ownership in a combined company with enhanced financial strength and

the commercial and R&D capabilities to continue to drive significant growth, especially in the Asia-Pacific region. I am incredibly proud and excited about the future impact of Prenetics and ACT on patient care.

Dr. Hua Chien Chen, CEO of ACT, says We are very excited in joining the Prenetics family. The investment and partnership of Prenetics into ACT will

significantly broaden our horizon in terms of product offerings, business strategy and vision. Our team is ready to make meaningful contributions to the enlarged group with our technical expertise, as well as our first-hand clinical experience. The

synergy and combined resources will enable us to provide more comprehensive solutions and better services to more patients and pharmaceutical companies in greater geographies.

Mr. Albert Wong, Chief Executive Officer of Hong Kong Science and Technology Parks Corporation, said, We are thrilled to witness this milestone,

which is a clear vote of confidence in Hong Kong s ambition to become a biomedical technology center of excellence. It was only last year when we saw the merger of two healthtech pioneers from the Hong Kong Science Park, ACT Genomics and

Sanomics. The acquisition by Science Park incubatee, Prenetics, is a testament to the high-quality innovation ecosystem and translational research infrastructure that have been established at the Park over the past 20 years. Backed by government

support and its unique advantages, Hong Kong is open to innovators from around the world who want to come and accelerate their future success.

Creating a Leader in Comprehensive Cancer Genetics and Precision Oncology

ACT s extensive product

Cancer Prevention Blood (specimen)

ACT Risk Screening of common hereditary cancers (67 genes)

ACTBRCA Germline mutations (2 genes)

Cancer Diagnostics Tumor tissue (specimen)

ACTOnco+ Targeted therapy (440 genes)

ACTDrug+ Screening of actionable genes (40 genes)

ACTLung Screening of lung cancer related actionable genes (13 genes)

ACTBRCA Somatic and germline mutations (2 genes)

ACTHRD Screening of HRR pathway genes (24 genes)

OncoSNAP Screening of ALK, ROS1, RET, EGFR, MET Exon 14 skipping, BRAF, HER2, KRAS, NRAS, PIK3CA

PD-L1 Screening of actionable genes (40 genes)

Cancer Recurrence Liquid biopsy (specimen)

ACTCerebra Screening of actionable genes (40 genes)

ACTMonitor Measure tumor load/monitor appearance of resistance clones

EGFR Screening of EGFR genes

Under the terms of the transaction

agreement, Prenetics has agreed to issue 19.9 million shares of Prenetics class A ordinary shares and pay $20 million in cash for a majority stake in ACT. Prenetics expects ACT to contribute approximately US$25-30 million in revenues in 2023. A separate presentation summary on the transaction can be found in this link:

ACT Genomics is an innovation-driven

cancer solution provider with offices in Taipei, Hong Kong, Singapore, Tokyo, Bangkok and UK. With our Next-Generation Sequencing (NGS) technology, CAP-accredited laboratories, experienced bioinformatics team,

and proprietary AI algorithms, we provide optimal cancer treatment planning, immunotherapy evaluation, cancer relapse & drug resistance monitoring, as well as cancer risk assessment services to medical professionals. Together, we Turn

Genomics into Action . To learn more about ACT Genomics, visit www.actgenomics.com.

Founded in 2014, Prenetics is a major global diagnostic and genetic testing company with the mission to bring health closer to millions of people globally and

decentralize healthcare by making the three pillars Consumer Health, Clinical Care and Medical & Cancer Genomics comprehensive and accessible to anyone, at anytime and anywhere. Prenetics is led by visionary entrepreneur,

Danny Yeung, with operations across nine locations, including The United Kingdom, Hong Kong, India, South Africa, and Southeast Asia. Prenetics develops consumer genetic testing and early colorectal cancer screening and provides COVID-19 testing, rapid point of care and at-home diagnostic testing and medical genetic testing. Prenetics is listed on NASDAQ with the ticker PRE. To learn more about

Prenetics, visit www.prenetics.com.

Investor Relations Contact:

Forward-Looking Statements

In addition to historical information, this release contains forward-looking statements within the meaning of the Private Securities Litigation

Reform Act of 1995. In some cases, you can identify forward-looking statements by terminology such as believe, may, will, estimate, continue, anticipate, intend,

should, plan, expect, predict, potential, or the negative of these terms or other similar expressions. These statements are based on estimates and forecasts and reflect the views,

assumptions, expectations, and opinions of Prenetics and ACT Genomics. Any such estimates and assumptions, expectations, forecasts, views or opinions, whether or not identified in this press release, should be regarded as indicative, preliminary and

for illustrative purposes only and should not be relied upon as being necessarily indicative of future results. These statements include, but are not limited to, statements by our management or the board regarding expectations for the closing of the

acquisition, statements of plans, objectives, and expectations of synergy between Prenetics and ACT by our management or the board or by ACT or ACT s management or board. Our expectations and beliefs regarding these matters may not materialize,

and actual results in future periods are subject to risks and uncertainties that could cause actual results to differ materially from those projected. Because of these uncertainties, you should not make any investment decisions based on our

estimates or forward-looking statements. All information provided in this press release is as of the date of this press release. Prenetics does not undertake any obligation to update any forward-looking statement, whether as a result of new

information, future developments, or otherwise, except as required under applicable law.