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Pharvaris Announces Data Highlighting Deucrictibant for the Treatment of HAE to be Presented at Upcoming Scientific Meetings

Key Takeaway: Pharvaris, a biopharmaceutical company, has announced the acceptance of multiple abstracts for presentation at several upcoming scientific meetings, highlighting their product Deucrictibant for treating hereditary angioedema (HAE). The presentations will detail the long-term safety, efficacy, and treatment outcomes associated with Deucrictibant. Key presentations will occur at the American College of Allergy, Asthma, & Immunology meeting, Canadian Society of Allergy and Clinical Immunology conference, and the Japanese Society of Allergology event. The company also is advancing a pivotal Phase 3 study for the on-demand treatment of HAE attacks and plans to initiate another pivotal study for prevention. This signifies a promising step forward in HAE treatment development.
Price reaction · baseline $20.82 (2024-10-15 close) · hit after-hours · clean, no other PHVS news in the window
day 0 close · peak
+3.3%

Market Sentiment Analysis

POSITIVE FACTORS

  • Pharvaris has multiple abstracts accepted at scientific meetings, showcasing the efficacy of Deucrictibant.
  • Upcoming presentations are expected to provide robust data on the treatment of hereditary angioedema.
  • The company is progressing with a pivotal Phase 3 study for both on-demand and prophylactic treatment.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+50%
120-day peak, hindsight
Typical move
8.8%
average across 6 past catalysts
Lead asset
Deucrictibant
Phase 3 · Hereditary Angioedema (HAE)

Full Press Release Details

ZUG, Switzerland, Oct. 16, 2024 (GLOBE NEWSWIRE) -- Pharvaris (Nasdaq: PHVS), a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to prevent and treat hereditary angioedema (HAE) attacks, today announced the acceptance of multiple abstracts at several upcoming scientific meetings. Presentation details are as follows:
American College of Allergy, Asthma, & Immunology’s Annual Scientific Meeting (ACAAI), Boston, October 24-28, 2024. Seven abstracts have been accepted for e-Poster presentation:
Poster: Long-Term Safety and Efficacy of Oral Deucrictibant for Hereditary Angioedema Prophylaxis: CHAPTER-1 Open-Label Extension Study
Speaker: John Anderson, M.D.
Format: e-Poster (R102)
Date, Time: Friday, Oct. 25, 2:00-2:15 p.m. EDT
Location: Monitor 21, Exhibit Hall A
Poster: Long-Term Treatment of Hereditary Angioedema Attacks With Oral Deucrictibant: RAPIDe-2 Extension Study Results
Speaker: John Anderson, M.D.
Format: e-Poster (R103)
Date, Time: Friday, Oct. 25, 2:15-2:30 p.m. EDT
Location: Monitor 21, Exhibit Hall A
Poster: Development Of A Novel Kinin Biomarker Assay For Characterization Of Bradykinin-Mediated Disorders
Speaker: Evangelia Pardali, Ph.D.
Format: e-Poster (R088)
Date, Time: Friday, Oct. 25, 2:30-2:45 p.m. EDT
Location: Monitor 20, Exhibit Hall A
Poster: Development of a HMWK Capillary Immunoblotting Assay for Characterization of Bradykinin-Mediated Disorders
Speaker: Evangelia Pardali, Ph.D.
Format: e-Poster (R090)
Date, Time: Friday, Oct. 25, 3:00-3:15 p.m. EDT
Location: Monitor 20, Exhibit Hall A
Poster: The Bradykinin Challenge Model In Non-Human Primates Successfully Predicted Efficacious Doses of Deucrictibant in Humans
Speaker: Juan Bravo, Ph.D.
Format: e-Poster (R112)
Date, Time: Friday, Oct. 25, 4:30-4:45 p.m. EDT
Location: Monitor 21, Exhibit Hall A
Poster: CHAPTER-1 Phase 2 Trial of Oral Bradykinin B2 Receptor Antagonist Deucrictibant for Hereditary Angioedema Prophylaxis
Speaker: H. James Wedner, M.D.
Format: e-Poster (R100)
Date, time: Friday, Oct. 25, 5:30-5:45 p.m. EDT
Location: Monitor 20, Exhibit Hall A
Poster: Prophylactic Treatment With Oral Deucrictibant Improves Hereditary Angioedema Disease Control and Health-Related Quality of Life
Speaker: H. James Wedner, M.D.
Format: e-Poster (R101)
Date, Time: Friday, Oct. 25, 5:45-6:00 p.m. EDT
Location: Monitor 20, Exhibit Hall A
Canadian Society of Allergy and Clinical Immunology (CSACI), Banff, Alberta, Canada, November 6-9, 2024. Three abstracts have been accepted for poster presentation.
Poster: Efficacy and Safety of Oral Deucrictibant, a Bradykinin B2 Receptor Antagonist, in Prophylaxis of HAE Attacks: Results of CHAPTER-1 Phase 2 Trial
Speaker: William H. Yang, M.D., FRCPC, FAAAAI
Date, Time: Thursday, Nov. 7, 12:30-1:00 p.m. MST (2:30-3:00 p.m. EST) and Friday, Nov. 8, 1:30-2:00 p.m. MST (3:30-4:00 p.m. EST)
Poster: Long-term safety and efficacy of oral deucrictibant, a bradykinin B2 receptor antagonist, for prophylaxis in HAE: CHAPTER-1 extension study results
Speaker: William H. Yang, M.D., FRCPC, FAAAAI
Date, Time: Thursday, Nov. 7, 12:30-1:00 p.m. MST (2:30-3:00 p.m. EST) and Friday, Nov. 8, 1:30-2:00 p.m. MST (3:30-4:00 p.m. EST)
Poster: Long-term efficacy and safety of oral bradykinin B2 receptor antagonist deucrictibant in treatment of HAE attacks: RAPIDe-2 extension study results
Speaker: Hugo Chapdelaine, M.D., FRCPC
Date, Time: Thursday, Nov. 7, 12:30-1:00 p.m. MST (2:30-3:00 p.m. EST) and Friday, Nov. 8, 1:30-2:00 p.m. MST (3:30-4:00 p.m. EST)
Japanese Society of Allergology (JSA), Kyoto, Japan, October 18-20, 2024. One abstract has been accepted for oral presentation.
Presentation: Efficacy and safety of oral deucrictibant IR capsule in HAE: RAPIDe-3 phase 3 trial design
Speaker: Prof. Michihiro Hide, M.D., Ph.D.
Format: Oral Presentation
Date, Time: Sunday, Oct. 20, 13:30-14:45 JST (12:30 -1:45 a.m. EDT)
The presentation slides and posters will be available on the Investors section of the Pharvaris website at: https://ir.pharvaris.com/news-events/events-presentations.
Pharvaris is a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to prevent and treat HAE attacks. By directly pursuing this clinically proven therapeutic target with novel small molecules, the Pharvaris team aspires to offer people with all types of bradykinin-mediated angioedema effective, well-tolerated, and easy-to-administer alternatives to treat attacks, both prophylactically and on-demand. With positive data in both Phase 2 prophylaxis and on-demand studies in HAE, Pharvaris is encouraged to further develop deucrictibant. Pharvaris is currently enrolling a pivotal Phase 3 study for the on-demand treatment of HAE attacks and plans to initiate a pivotal Phase 3 study of deucrictibant for the prevention of HAE attacks in the coming months. For more information, visit https://pharvaris.com/.

Frequently Asked Questions

What is the focus of Pharvaris's research?

Pharvaris develops oral bradykinin B2 receptor antagonists for hereditary angioedema.

When is the ACAAI Annual Scientific Meeting?

The ACAAI meeting takes place from October 24-28, 2024, in Boston.

How many abstracts did Pharvaris have accepted at JSA?

Pharvaris had one abstract accepted for oral presentation at JSA.

What is the name of the Phase 3 study by Pharvaris?

Pharvaris is enrolling a pivotal Phase 3 study for on-demand HAE treatment.

Where can I find presentation materials from Pharvaris?

Presentation materials will be available in the Investors section of the Pharvaris website.

Last updated: Oct 16, 2024