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Profusa Welcomes Former Acting U.S. Veterans Affairs Secretary Peter O'Rourke as Lead Independent Director; Adds Seasoned Finance Executive Fred Knechtel as CFO Board addition served in the Trump Administration, overseei

Key Takeaway: Profusa, Inc. announces two significant leadership appointments following its business combination with NorthView Acquisition Corp. Former Acting U.S. Secretary of Veterans Affairs Peter O'Rourke has been appointed as Lead Independent Director, while seasoned finance executive Fred Knechtel joins as Chief Financial Officer. Both leaders bring extensive experience that will support Profusa's growth and commercialization of its innovative biosensor technology. Their appointments are seen as pivotal for the company's future directions and operations.

Market Sentiment Analysis

POSITIVE FACTORS

  • Appointment of Peter O'Rourke as Lead Independent Director adds significant leadership experience.
  • Fred Knechtel's extensive background in finance and operations enhances the executive team.
  • Both leaders express confidence in Profusa's transformative technology and potential for commercialization.
  • Profusa is preparing to bring innovative biosensor technology to global markets.

Full Press Release Details

Profusa Welcomes Former Acting U.S. Veterans
Peter O'Rourke as Lead Independent Director;
Finance Executive Fred Knechtel as CFO
Board addition served in the Trump Administration, overseeing 1,300
facilities serving more than 9 million veterans; New CFO has led finance and operations at companies including Northrop Grumman, Stanley
Black & Decker, and DuPont
Profusa, Inc. ("Profusa" or the "Company")
(NASDAQ: PFSA), a commercial stage digital health company pioneering the next generation of technology platform enabling the continuous
monitoring of an individual's biochemistry, announces two major leadership additions as of the close of the business combination
with NorthView Acquisition Corp (NVAC). Peter O'Rourke, former Acting U.S. Secretary of Veterans Affairs (VA), has joined the Board
of Directors as lead independent director, and Fortune 500 financial executive Fred Knechtel has been named Chief Financial Officer.
"Profusa is at an inflection point as we
prepare to bring our transformative biosensor platform to global markets," said Ben Hwang, Ph.D., CEO of Profusa. "Peter brings
extensive leadership experience, having overseen one of the largest integrated healthcare systems in the United States, serving more than
9 million veterans across 1,300 facilities during the first Trump administration. His ability to navigate complex organizations and drive
large-scale innovation will be invaluable as we grow. Fred, who has long been a trusted partner to Profusa as a founder and CFO of NorthView
Acquisition Corp., brings deep expertise in operations, capital markets, and investor engagement. Together, their insights will strengthen
our path to commercialization."
Mr. O'Rourke has a distinguished record
as a presidential cabinet member, strategic advisor, and corporate executive. His career spans leadership in government, mergers and acquisitions,
market development, and corporate governance. As a senior executive in both private and public companies, he has helped organizations
scale, innovate, and deliver shareholder value.
"It's a privilege to join Profusa's
board at such a pivotal moment," said Mr. O'Rourke. "Profusa's biosensor technology has the potential to transform
how we understand and monitor human health. I look forward to working with the Board and leadership team to accelerate growth, support
commercialization, and maximize shareholder value."
Mr. Knechtel has led finance and operations from
start-ups to publicly traded large cap companies. As CFO, he guided organizations operating in the life sciences, automotive, consumer
products, chemical and metals recycling industries through profitable growth, capital restructure, mergers/acquisitions/sales and IPOs.
Companies he worked at include Northrop Grumman, Stanley Black and Decker, DuPont, Remy International, Sims Metal Management and GENEWIZ
Mr. Knechtel added, "I believe that Profusa
possesses game-changing technology that will set the stage for how we maintain our health for years to come. Combined with an innovative
financial strategy to manage our balance sheet1, I'm looking forward to collaborating with the management team and board to drive
our progress and growth in the coming years."
Based in Berkeley, Calif., Profusa is a commercial
stage digital health company led by visionary scientific founders, an experienced management team and a world-class board of directors
in the development of a new generation of tissue-integrated sensors to detect and continuously transmit actionable, medical-grade data
for personal and medical use. With its long-lasting, injectable and affordable biosensors and its intelligent data platform, Profusa aims
to provide people with a personalized biochemical signature rooted in data that clinicians can trust and rely on.
"LUMEE", "PROFUSA" and
the PROFUSA logo are registered trademarks of Profusa Inc. in the United States, Canada, European Union, China, Japan, South Korea and
Australia. For more information, visit https://profusa.com.
Special Note Regarding Forward-Looking Statements
Certain statements in this press release may be
considered "forward-looking statements" within the meaning of the "safe harbor" provisions of the United States
Private Securities Litigation Reform Act of 1995. Forward-looking statements generally relate to future events or future financial or
operating performance of Profusa. In some cases, you can identify forward-looking statements by terminology such as "anticipate,"
"believe," "continue," "could," "estimate," "expect," "forecast,"
"future," "intend," "may," "might," "plan," "possible," "potential,"
"predict," "project," "propose," "seek," "should," "strive," "will,"
or "would" or the negatives of these terms or variations of them or similar terminology. Such forward-looking statements are
subject to risks, uncertainties, and other factors which may be beyond the control of Profusa and could cause actual results to differ
materially from those expressed or implied by such forward-looking statements, including risks regarding the highly volatile nature of
the price of Bitcoin and other cryptocurrencies, as well as the risk that the Company's stock price may be highly correlated to the price
of the digital assets that it holds. These forward-looking statements are based upon estimates and assumptions that, while considered
reasonable by Profusa and its management, are inherently uncertain. Profusa cautions you that these statements are based on a combination
of facts and factors currently known and projections of the future, which are inherently uncertain. There are risks and uncertainties
described in our Form S-1 Registration Statement (Registration No. 333-289461) filed with the SEC on August 11, 2025, and described in
other documents filed by Profusa from time to time with the SEC. These filings may identify and address other important risks and uncertainties
that could cause actual events and results to differ materially from those contained in the forward-looking statements. Profusa cannot
assure you that the forward-looking statements in this communication will prove to be accurate.
Investor and Media Contacts email: info@coreir.com
phone: 1 (212) 655-0924

Frequently Asked Questions

Who joined Profusa's board as lead independent director?

Peter O'Rourke, former Acting U.S. Secretary of Veterans Affairs, joined.

What position did Fred Knechtel assume at Profusa?

Fred Knechtel has been appointed Chief Financial Officer.

How many veterans did O'Rourke oversee in his previous role?

He oversaw services for over 9 million veterans across 1,300 facilities.

What is Profusa's main technological focus?

Profusa is developing tissue-integrated sensors for continuous health monitoring.

Where is Profusa based?

Profusa is based in Berkeley, California.

Last updated: Aug 11, 2025