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Vaxcyte to Host Webcast and Conference Call to Present Topline Data from OPUS-1, the Pivotal Adult Phase 3 Trial of VAX-31, the Company’s 31-Valent Pneumococcal Conjugate Vaccine Candidate

Key Takeaway: Vaxcyte, Inc. announced a webcast and conference call to present topline data from the OPUS-1 Phase 3 trial of its 31-valent pneumococcal conjugate vaccine, VAX-31. The trial evaluates the vaccine's safety, tolerability, and immunogenicity. The event is scheduled for October 5, 2026, and will also be archived on the company's website.

Market Sentiment Analysis

POSITIVE FACTORS

  • Vaxcyte is presenting topline data from a pivotal Phase 3 trial.
  • VAX-31 aims to prevent serious pneumococcal diseases.
  • The company is innovating with high-fidelity vaccines.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+35%
120-day peak, hindsight
Typical move
10.5%
average across 6 past catalysts
Cash runway
~17 mo
Low dilution risk
Lead asset
VAX-31
Phase 3 · Pneumococcal Vaccines

Full Press Release Details

SAN CARLOS, Calif., Oct. 04, 2026 (GLOBE NEWSWIRE) -- Vaxcyte, Inc. (Nasdaq: PCVX), a clinical-stage vaccine innovation company, today announced it will host a webcast and conference call tomorrow, October 5, 2026 at 8:00 a.m. ET / 5:00 a.m. PT to present topline data from the OPUS-1 adult pivotal Phase 3 trial evaluating the safety, tolerability and immunogenicity of VAX-31, the Company’s 31-valent pneumococcal conjugate vaccine (PCV) candidate designed to prevent invasive pneumococcal disease (IPD) and pneumococcal pneumonia.
To participate in the conference call, please dial 800-445-7795 (domestic) or 785-424-1699 (international) and refer to conference ID PCVX1005. A live webcast of the conference call will also be available on the investor relations page of the Vaxcyte corporate website at www.vaxcyte.com.
After the live webcast, the event will remain archived on the Vaxcyte website for at least 30 days.
About Vaxcyte Vaxcyte is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. VAX-31, a 31-valent PCV candidate being evaluated in the OPUS Phase 3 adult clinical program and in a Phase 2 infant clinical program, is being developed for the prevention of IPD and is the broadest-spectrum PCV candidate in the clinic today. VAX-24, a 24-valent PCV candidate, has generated positive Phase 2 clinical results in both adults and infants and is designed to cover more serotypes than any PCV on-market. VAX-31 and VAX-24 are designed to improve upon standard-of-care PCVs by covering the serotypes in circulation that cause a significant portion of IPD and are associated with high case-fatality rates, antibiotic resistance and meningitis, while maintaining coverage of previously circulating strains. VAX-XL, in earlier-stage development, also leverages the Company’s carrier-sparing, site-specific conjugation technology with the aim of further expanding coverage to deliver the broadest-spectrum candidate in the Company’s PCV franchise.
VAX-A1 is a prophylactic vaccine candidate designed to provide broad, strain-independent protection against disease caused by Group A Strep and is currently being evaluated in a Phase 1 clinical study in adults. Group A Strep remains a significant global cause of morbidity and mortality across both adult and pediatric populations and is a leading driver of antibiotic use, underscoring the substantial public health burden.
Vaxcyte is re-engineering the way highly complex vaccines are made through XpressCF®, its cell-free protein synthesis platform exclusively licensed from Sutro Biopharma, Inc. Unlike conventional cell-based approaches, the Company’s system for producing difficult-to-make proteins and antigens is intended to develop and deliver high-fidelity vaccines with enhanced immunological benefits. Vaxcyte’s pipeline also includes VAX-GI, a vaccine candidate designed to prevent Shigella. For more information, visit www.vaxcyte.com.

Contacts: Patrick Ryan, Executive Director, Corporate Affairs Vaxcyte, Inc. 415-606-5135 media@vaxcyte.com

Frequently Asked Questions

What is the purpose of the OPUS-1 trial?

The OPUS-1 trial evaluates the safety, tolerability, and immunogenicity of VAX-31.

When will the Vaxcyte webcast take place?

The webcast is scheduled for October 5, 2026, at 8:00 a.m. ET.

How can I access the Vaxcyte conference call?

Participants can dial 800-445-7795 domestically or 785-424-1699 internationally.

What is VAX-31 designed to prevent?

VAX-31 is designed to prevent invasive pneumococcal disease and pneumococcal pneumonia.

Last updated: Oct 4, 2026