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Vaxcyte to Host Webcast and Conference Call to Present Topline Results from VAX-24 Infant Phase 2 Study

Key Takeaway: Vaxcyte, Inc. will host a webcast and conference call on March 31, 2025, to present topline results from its VAX-24 Phase 2 study. This study evaluates the safety and immunogenicity of VAX-24, a 24-valent pneumococcal conjugate vaccine, compared to Prevnar 20 in healthy infants. The results are anticipated to provide insights into the vaccine's effectiveness against invasive pneumococcal disease.
Price reaction · baseline $69.46 (2025-03-28 close) · 1 other PCVX headline(s) in the window, move may be shared
day 0 close
-45.6%
day 1
-53.6%
day 3 · peak
-56%

Market Sentiment Analysis

POSITIVE FACTORS

  • Vaxcyte is presenting topline results from a promising Phase 2 study.
  • The VAX-24 vaccine aims to cover more serotypes than existing infant vaccines.
  • The company is innovating vaccine production with advanced synthetic techniques.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+1%
120-day peak, hindsight
Typical move
27.5%
average across 2 past catalysts
Cash runway
~19 mo
Low dilution risk
Lead asset
31 valent pneumococcal conjugate vaccine
Phase 3 · Pneumococcal Vaccines

Full Press Release Details

SAN CARLOS, Calif., March 30, 2025 (GLOBE NEWSWIRE) -- Vaxcyte, Inc. (Nasdaq: PCVX), a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, today announced it will hold a webcast and conference call tomorrow, March 31, 2025, at 8:00 a.m. Eastern Time to present topline results from the VAX-24 infant Phase 2 study. This study is evaluating the safety, tolerability and immunogenicity of VAX-24, the Company’s 24-valent pneumococcal conjugate vaccine (PCV) candidate designed to prevent invasive pneumococcal disease (IPD), compared to Prevnar 20®in healthy infants.
To participate in the conference call, please dial 800-445-7795 (domestic) or 785-424-1699 (international) and refer to conference ID PCVX0331. A live webcast of the conference call will also be available on the investor relations page of the Vaxcyte corporate website atwww.vaxcyte.com. After the live webcast, the event will remain archived on the Vaxcyte website for 30 days.
About VaxcyteVaxcyte is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. The Company is developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. VAX-31, a 31-valent PCV candidate advancing to a Phase 3 adult clinical program and currently being evaluated in a Phase 2 infant clinical program, is being developed for the prevention of IPD in adults and infants and is the broadest-spectrum PCV candidate in the clinic today. VAX-24, the Company’s 24-valent PCV candidate, is designed to cover more serotypes than any infant PCV on-market and is currently being evaluated in a Phase 2 infant study. Both VAX-31 and VAX-24 are designed to improve upon the standard-of-care PCVs by covering the serotypes in circulation that are responsible for a significant portion of IPD and are associated with high case-fatality rates, antibiotic resistance and meningitis, while maintaining coverage of previously circulating strains that are currently contained through continued vaccination practice.
Vaxcyte is re-engineering the way highly complex vaccines are made through modern synthetic techniques, including advanced chemistry and the XpressCF™ cell-free protein synthesis platform, exclusively licensed from Sutro Biopharma, Inc. Unlike conventional cell-based approaches, the Company’s system for producing difficult-to-make proteins and antigens is intended to accelerate its ability to efficiently create and deliver high-fidelity vaccines with enhanced immunological benefits. Vaxcyte’s pipeline also includes VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease; and VAX-GI, a vaccine candidate designed to prevent Shigella. Vaxcyte is driven to eradicate or treat invasive bacterial infections, which have serious and costly health consequences when left unchecked. For more information, visitwww.vaxcyte.com.

Frequently Asked Questions

What is the purpose of the VAX-24 study?

The VAX-24 study evaluates the safety, tolerability, and immunogenicity of the 24-valent pneumococcal conjugate vaccine in infants.

When will Vaxcyte present the study results?

Vaxcyte will present the topline results on March 31, 2025, at 8:00 a.m. Eastern Time.

How can I participate in the conference call?

To participate, dial 800-445-7795 for domestic or 785-424-1699 for international calls, using conference ID PCVX0331.

What is unique about the VAX-24 vaccine?

VAX-24 is designed to cover more serotypes than any other infant pneumococcal vaccine currently available.

Last updated: Mar 30, 2025