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Palisade Bio Announces Participation in Two Upcoming Investor Conferences

Key Takeaway: Palisade Bio, Inc. announced its participation in two investor conferences in March 2026, where management will present and hold meetings. The company is advancing its lead program, PALI-2108, which has shown a 100% clinical response in a Phase 1b trial for ulcerative colitis. Palisade is preparing for a Phase 2 study to further evaluate the drug's efficacy and safety.
Price reaction · baseline $1.77 (2026-02-27 close) · hit pre-market · clean, no other PALI news in the window
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POSITIVE FACTORS

  • Palisade Bio is participating in two significant investor conferences.
  • The company's lead program, PALI-2108, shows promising results in clinical trials.
  • Palisade aims to transform PDE4 biology into safer oral therapies.

CONCERNS & RISKS

  • The company is still in early stages of clinical development.
  • There are inherent risks in relying on PALI-2108's clinical trial results.

Full Press Release Details

Carlsbad, CA, March 02, 2026 (GLOBE NEWSWIRE) --Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Company”), a clinical-stage biopharmaceutical company developing next-generation, once-daily, oral PDE4 inhibitor prodrugs designed for targeted delivery to the terminal ileum and colon, today announced that management will participate in two upcoming investor conferences taking place during March 2026. Details are as follows:
TD Cowen 46th Annual Health Care ConferenceDate/time:March 2, 2026 at 3:10 PM ESTLocation:Boston Mariott Copley Place, Boston, MAFormat:In-person presentation & investor meetingsWebcast link:Register here
Investors registered to attend the conference who wish to meet with Palisade Bio management should contact the TD Cowen one-on-one desk to request a meeting.
Leerink Partners 2026 Global Healthcare ConferenceDate:March 8-11, 2026Location:W South Beach, Miami, FLFormat:One-on-one investor meetings
Investors registered to attend the conference who wish to meet with Palisade Bio management should contact the Leerink one-on-one desk to request a meeting.
About Palisade Bio
Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Company”) is a clinical-stage biopharmaceutical company advancing a next generation oral PDE4 inhibitor prodrugs designed to improve pharmacology, tolerability and convenience for patients with inflammatory and fibrotic diseases. Through its differentiated prodrug platform and precision pharmacology strategy, Palisade Bio is committed to transforming proven PDE4 biology into better, safer oral therapies for patients living with chronic inflammatory and fibrotic diseases.
The Company’s lead program, PALI-2108, is a once-daily oral PDE4 inhibitor prodrug designed to be selectively bioactivated in the ileum and colon, initiating targeted PDE4 inhibition at sites of disease while enabling systemic distribution of the active drug. In a recently reported Phase 1b trial, PALI-2108 achieved a 100% clinical response in the UC cohort, with no serious adverse events, favorable tolerability and pharmacokinetics consistent with localized activation in the lower intestine, low systemic exposure, and controlled release within the GI tract.
Palisade Bio is now advancing towards a Phase 2 clinical study in UC designed to evaluate clinical remission, response and pharmacodynamic biomarkers over 12 weeks, with an extension phase assessing maintenance of remission. In addition, the Company is completing early studies in fibrostenotic crohn’s disease to further characterize PALI-2108’s safety, pharmacology and potential therapeutic benefit across inflammatory bowel disease indications. For more information, please go towww.palisadebio.com.
Forward Looking Statements
Any statements contained in this communication that are not statements of historical fact may be deemed to be forward-looking statements for purposes of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include but are not limited to: statements regarding the timing and results of clinical trials, the potential mechanisms of action and therapeutic benefits of PALI-2108, and plans for regulatory submissions. These forward-looking statements are based on the Company’s current expectations. Forward-looking statements involve risks and uncertainties. Important factors that could cause actual results to differ materially from those reflected in the Company’s forward-looking statements include, among others, the timing of enrollment, commencement and completion of the Company’s clinical trials; the Company’s reliance on PALI-2108, and its early stage of clinical development; the risk that prior results, such as signals of safety, clinical response, dosing or durability of effect, observed from preclinical or clinical trials, will not be replicated or will not continue in ongoing or future studies or clinical trials involving the Company’s product candidates in clinical trials focused on the same or different indications; and other factors that are described in the “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” sections of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024, filed with the Securities and Exchange Commission (“SEC”) on March 24, 2025, and the Quarterly Reports on Form 10-Q or other SEC filings that are filed thereafter. Investors are cautioned not to put undue reliance on these forward-looking statements. These forward-looking statements speak only as of the date hereof, and the Company expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in the Company’s expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based.
Investor Relations Contact

Frequently Asked Questions

What are the dates for Palisade Bio's investor conferences?

Palisade Bio will participate in conferences on March 2 and March 8-11, 2026.

What is PALI-2108 designed for?

PALI-2108 is designed as a once-daily oral PDE4 inhibitor for inflammatory diseases.

What were the results of the Phase 1b trial for PALI-2108?

The Phase 1b trial reported a 100% clinical response in the ulcerative colitis cohort.

Where will the TD Cowen conference take place?

The TD Cowen conference will be held at the Boston Marriott Copley Place.

What is the focus of Palisade Bio's upcoming Phase 2 study?

The Phase 2 study will evaluate clinical remission and pharmacodynamic biomarkers.

Last updated: Mar 2, 2026