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ORIC® Pharmaceuticals to Report Combination Dose Optimization Data From Phase 1b Trial of Rinzimetostat in Patients with mCRPC

Key Takeaway: ORIC Pharmaceuticals will present combination dose optimization data from its Phase 1b trial of rinzimetostat for metastatic castration resistant prostate cancer (mCRPC) on March 31, 2026. The conference call will include a live Q&A session and will be accessible via the company's website. This trial aims to enhance treatment options for patients facing therapeutic resistance.
Price reaction · baseline $12.38 (2026-03-26 close) · hit pre-market · 2 other ORIC headline(s) in the window, move may be shared
day 0 close · peak
-2.6%

Market Sentiment Analysis

POSITIVE FACTORS

  • ORIC Pharmaceuticals is advancing its clinical trials for rinzimetostat.
  • The upcoming conference call will provide important data on dose optimization.
  • The company is focused on addressing therapeutic resistance in cancer.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+58%
120-day peak, hindsight
Typical move
10.1%
average across 6 past catalysts
Cash runway
~36 mo
Minimal dilution risk
Lead asset
ORIC-944
Phase 1 · Metastatic Prostate Cancer

Full Press Release Details

SOUTH SAN FRANCISCO, Calif. and SAN DIEGO, March 27, 2026 (GLOBE NEWSWIRE) -- ORIC Pharmaceuticals, Inc. (Nasdaq: ORIC), a clinical stage oncology company focused on developing treatments that address mechanisms of therapeutic resistance, today announced that it will report combination dose optimization data from the Phase 1b trial of rinzimetostat (ORIC-944) in patients with metastatic castration resistant prostate cancer (mCRPC) in a conference call and webcast on Tuesday, March 31, 2026 at 4:30pm ET.
To join the conference call via phone and participate in the live Q&A session, please pre-register onlinehereto receive a telephone number and unique passcode required to enter the call. A live webcast and audio archive of the conference call will be available through the investor section of the company’s website at www.oricpharma.com. The webcast will be available for replay for 90 days following the presentation.
About ORIC Pharmaceuticals, Inc.ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives byOvercoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib (ORIC-114), a brain-penetrant inhibitor targeting EGFR exon 20 and EGFR PACC mutations, being developed for NSCLC. ORIC has offices in South San Francisco and San Diego, California. For more information, please go towww.oricpharma.com, and follow us onXorLinkedIn.

Contact:Dominic Piscitelli, Chief Financial Officerdominic.piscitelli@oricpharma.cominfo@oricpharma.com

Frequently Asked Questions

What is the focus of ORIC Pharmaceuticals?

ORIC Pharmaceuticals focuses on developing treatments that address mechanisms of therapeutic resistance in cancer.

When will the rinzimetostat trial data be reported?

The trial data will be reported on March 31, 2026, during a conference call.

How can I join the conference call?

Participants can pre-register online to receive a telephone number and passcode for the call.

What is rinzimetostat used for?

Rinzimetostat is being developed for treating metastatic castration resistant prostate cancer (mCRPC).

Last updated: Mar 27, 2026