Recent Updates
Recently added Catalysts
OKYO Positive Sentiment Score: 75/100

OKYO Pharma Announces Director Acquires Shares London and New York, NY

Key Takeaway: OKYO Pharma Limited has announced that Non-Executive Director John Brancaccio acquired 5,000 shares at $1.61, increasing his total holding to 31,201 shares. The company is focused on developing therapies for neuropathic corneal pain and inflammatory eye diseases. Recently, OKYO reported positive results from a Phase 2a trial on its investigational drug urcosimod, showing pain reduction in neuropathic corneal pain subjects. The company is planning to initiate a Phase 2b/3 study with approximately 150 subjects in the near future.

Market Sentiment Analysis

POSITIVE FACTORS

  • Director John Brancaccio acquired additional shares, indicating confidence in the company.
  • Positive outcomes from recent Phase 2a trial for neuropathic corneal pain.
  • Significant pain reduction demonstrated in previously conducted trials.

Full Press Release Details

OKYO Pharma Announces Director Acquires Shares
and New York, NY, March 19, 2026. OKYO Pharma Limited (NASDAQ: OKYO), a clinical-stage biopharmaceutical company developing investigational
therapies for the treatment of neuropathic corneal pain (NCP) and for inflammatory eye diseases, today announced it has been informed
that John Brancaccio, Non-Executive Director, has acquired 5,000 of the Company's ordinary shares on NASDAQ at $1.61, bringing
his total holding to 31,201 shares.
Urcosimod (formerly called OK-101)
Urcosimod is a lipid conjugated chemerin peptide agonist of the ChemR23 G-protein coupled receptor which is typically found on immune
cells of the eye responsible for the inflammatory response, as well as on neurons and glial cells in the dorsal root ganglion. Urcosimod
has been shown to produce anti-inflammatory and pain-reducing activities in a mouse model of dry eye disease and in a neuropathic corneal
pain mouse model, respectively. OKYO recently announced positive data on NCP pain reduction in a randomized, placebo-controlled, double-masked
Phase 2a trial involving 18 neuropathic corneal pain subjects. Urcosimod has shown significant pain reduction in an earlier 240 subject
Phase 2, multi-center, double-masked, placebo-controlled trial in DED, which supports the development rationale in NCP.
OKYO Pharma Limited (Nasdaq: OKYO) is a clinical-stage biopharmaceutical company developing innovative therapies for the treatment of
neuropathic corneal pain (NCP) and inflammatory eye diseases, with ordinary shares listed for trading on the Nasdaq Capital Market. OKYO
is focused on the discovery and development of novel molecules to treat neuropathic corneal pain and other ocular diseases. OKYO recently
completed a successful phase 2 trial of its flagship drug urcosimod in subjects with NCP and plans to initiate a ~150 subject Phase 2b/3
multiple-dose study of urcosimod to treat NCP in the first half of this year.
further information, please visit www.okyopharma.com.

Frequently Asked Questions

Who acquired shares in OKYO Pharma recently?

John Brancaccio, a Non-Executive Director, acquired 5,000 ordinary shares.

What is Urcosimod used for?

Urcosimod is developed for treating neuropathic corneal pain and inflammatory eye diseases.

What are the results of Urcosimod in trials?

Urcosimod showed significant pain reduction in Phase 2 trials for NCP and dry eye disease.

When will the next study for Urcosimod begin?

OKYO plans to start a Phase 2b/3 multiple-dose study of Urcosimod in the first half of this year.

Last updated: Mar 19, 2026