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OKYO Pharma Announces Chief Development Officer and Director Acquires Shares London and New York, NY

Key Takeaway: OKYO Pharma Limited has announced that Gary Jacob, the Chief Development Officer and Director, has purchased nearly 31,000 ordinary shares of the company, raising his total holdings. This action comes alongside reports of positive outcomes from a randomized Phase 2a trial focusing on the company's investigational drug, urcosimod, for treating neuropathic corneal pain (NCP). Following the success of this trial, OKYO plans to start a larger Phase 2b/3 study within the next few months to further assess the efficacy of urcosimod.

Market Sentiment Analysis

POSITIVE FACTORS

  • Gary Jacob, Chief Development Officer, shows confidence by acquiring shares.
  • Recent positive data from Phase 2a trial suggests effective pain reduction in NCP.
  • Plans to initiate a Phase 2b/3 study indicate ongoing commitment to research and development.

Full Press Release Details

Pharma Announces Chief Development Officer and Director Acquires Shares
and New York, NY, March 19, 2026. OKYO Pharma Limited (NASDAQ: OKYO), a clinical-stage biopharmaceutical company developing investigational
therapies for the treatment of neuropathic corneal pain (NCP) and for inflammatory eye diseases, today announced it has been informed
that Gary Jacob, Chief Development Officer and Director, has acquired 30,980 of the Company's ordinary shares on NASDAQ at $1.59,
bringing his total holding to 108,920 shares.
Urcosimod (formerly called OK-101)
is a lipid conjugated chemerin peptide agonist of the ChemR23 G-protein coupled receptor which is typically found on immune cells of
the eye responsible for the inflammatory response, as well as on neurons and glial cells in the dorsal root ganglion. Urcosimod has been
shown to produce anti-inflammatory and pain-reducing activities in a mouse model of dry eye disease and in a neuropathic corneal pain
mouse model, respectively. OKYO recently announced positive data on NCP pain reduction in a randomized, placebo-controlled, double-masked
Phase 2a trial involving 18 neuropathic corneal pain subjects. Urcosimod has shown significant pain reduction in an earlier 240 subject
Phase 2, multi-center, double-masked, placebo-controlled trial in DED, which supports the development rationale in NCP.
Pharma Limited (Nasdaq: OKYO) is a clinical-stage biopharmaceutical company developing innovative therapies for the treatment of neuropathic
corneal pain (NCP) and inflammatory eye diseases, with ordinary shares listed for trading on the Nasdaq Capital Market. OKYO is focused
on the discovery and development of novel molecules to treat neuropathic corneal pain and other ocular diseases. OKYO recently completed
a successful phase 2 trial of its flagship drug urcosimod in subjects with NCP and plans to initiate a ~150 subject Phase 2b/3 multiple-dose
study of urcosimod to treat NCP in the first half of this year.
further information, please visit www.okyopharma.com.

Frequently Asked Questions

Who acquired shares in OKYO Pharma recently?

Gary Jacob, Chief Development Officer and Director, acquired 30,980 shares.

What is Urcosimod used to treat?

Urcosimod is developed for neuropathic corneal pain and inflammatory eye diseases.

What phase trials has Urcosimod completed?

Urcosimod recently completed a successful Phase 2 trial for neuropathic corneal pain.

What results did OKYO report from the Phase 2a trial?

OKYO reported significant pain reduction in neuropathic corneal pain subjects.

When will the Phase 2b/3 study of Urcosimod begin?

The Phase 2b/3 multiple-dose study of Urcosimod is set to start in the first half of 2026.

Last updated: Mar 19, 2026