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OKYO Pharma Announces Chairman Acquires Shares

Key Takeaway: OKYO Pharma Limited announced that Executive Chairman Gabriele Cerrone acquired an additional 50,000 shares, increasing his stake to 29.12%. The company is developing innovative therapies for dry eye disease and neuropathic corneal pain, with the drug OK-101 demonstrating anti-inflammatory efficacy in trials. A recently completed Phase 2 trial for OK-101 to treat dry eye disease has shown statistical significance, and plans for a Phase 2 trial targeting neuropathic corneal pain are underway.
Price reaction · baseline $1.03 (2024-09-09 close) · hit after-hours · clean, no other OKYO news in the window
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Market Sentiment Analysis

POSITIVE FACTORS

  • Gabriele Cerrone, the Executive Chairman, is investing further in the company by acquiring additional shares.
  • OK-101 shows promising results in treating dry eye disease and neuropathic corneal pain.
  • The company is progressing with upcoming Phase 2 trials for its innovative therapies.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+13%
120-day peak, hindsight
Typical move
9%
average across 7 past catalysts
Lead asset
OK-101
Phase 2 · Dry Eye Disease

Full Press Release Details

LONDON and NEW YORK, Sept. 10, 2024 (GLOBE NEWSWIRE) -- OKYO Pharma Limited (NASDAQ: OKYO), a clinical-stage biopharmaceutical company developing innovative ocular therapies for the treatment of inflammatory dry eye disease (DED), a multi-billion-dollar market, and anterior ocular segment diseases including neuropathic corneal pain (NCP), an ocular condition associated with pain but without an FDA approved therapy, announced today that it has been notified that Panetta Partners Limited, an entity in which Gabriele Cerrone, the Executive Chairman, has a beneficial interest, purchased 50,000 of the Company’s ordinary shares on NASDAQ at a price of US$1.03 per share. This brings the total shareholding of Mr Cerrone to 9,851,570 shares which is 29.12% of issued share capital.
OK-101 is a lipid conjugated chemerin peptide agonist of the ChemR23 G-protein coupled receptor which is typically found on immune cells of the eye responsible for the inflammatory response. OK-101 was developed using a membrane-anchored-peptide technology to produce a novel long-acting drug candidate for treating dry eye disease. OK-101 has been shown to produce anti-inflammatory and pain-reducing efficacy signals in mouse models of dry eye disease and corneal neuropathic pain (NCP), respectively, and is designed to combat washout through the inclusion of the lipid anchor built into the drug molecule to enhance the residence time of OK-101 within the ocular environment. OK-101 recently showed statistical significance in multiple endpoints in a recently completed Phase 2, multi-center, double-blind, placebo-controlled trial of OK-101 to treat DED.
OKYO Pharma Limited (NASDAQ: OKYO) is a clinical stage biopharmaceutical company developing innovative therapies for the treatment of DED and NCP, with ordinary shares listed for trading on the NASDAQ Capital Market. OKYO is focused on the discovery and development of novel molecules to treat inflammatory DED and ocular pain. In addition to the recently completed Phase 2 DED trial, OKYO also has plans underway for the opening of a Phase 2 trial for OK-101 to treat NCP in patients with this debilitating condition. For further information, please visit www.okyopharma.com.
OKYO Pharma Limited Gary S. Jacob, Chief Executive Officer 917-497-7560
Business Development & Investor Relations Paul Spencer +44 (0)20 7495 2379

Frequently Asked Questions

What conditions does OKYO Pharma focus on treating?

OKYO Pharma develops therapies for inflammatory dry eye disease (DED) and neuropathic corneal pain (NCP).

What is OK-101 used for?

OK-101 is developed as a treatment for dry eye disease and neuropathic corneal pain.

What recent trial did OKYO complete for OK-101?

OKYO completed a Phase 2 trial showing statistical significance in treating dry eye disease.

Who holds a significant stock in OKYO Pharma?

Gabriele Cerrone, the Executive Chairman, holds 29.12% of the company's shares.

How does OK-101 enhance its effect in the eye?

OK-101 includes a lipid anchor to increase its residence time in the ocular environment.

Last updated: Sep 10, 2024