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Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - June 2, 2026

Key Takeaway: Orchestra BioMed announced the grant of stock options to five new employees as part of its 2025 New Hire Inducement Plan, in compliance with Nasdaq Listing Rule 5635(c)(4). The company is focused on advancing its flagship product candidates, AVIM Therapy and Virtue SAB, which are in pivotal clinical trials and target significant market opportunities in hypertension and atherosclerotic artery disease.
Price reaction · baseline $3.91 (2026-06-02 close) · hit pre-market · clean, no other OBIO news in the window
day 0 close · peak
-1.3%

Market Sentiment Analysis

POSITIVE FACTORS

  • Orchestra BioMed granted stock options to new employees, indicating growth.
  • The company is advancing innovative therapies with significant market potential.
  • Strategic partnerships with leading medical device companies enhance credibility.

Full Press Release Details

NEW HOPE, Pa., June 02, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through strategic partnerships with market-leading global medical device companies, reported today that, on June 1, 2026, the Compensation Committee of the Orchestra BioMed Board of Directors granted stock options to purchase an aggregate of 85,500 shares of the Company’s common stock to five newly hired employees. The awards were granted pursuant to the Orchestra Biomed Holdings, Inc. 2025 New Hire Inducement Plan as an inducement material to each new employee entering employment with Orchestra Biomed, in accordance with Nasdaq Listing Rule 5635(c)(4). The stock options granted to each new employee will vest over a four-year period.
Orchestra Biomed is providing this information in accordance with Nasdaq Listing Rule 5635(c)(4).
About Orchestra BioMedOrchestra BioMed is a biomedical innovation company accelerating high-impact technologies to patients through strategic collaborations with market-leading global medical device companies. The Company’s two flagship product candidates - Atrioventricular Interval Modulation (AVIM) Therapy and Virtue® Sirolimus AngioInfusion™ Balloon (Virtue SAB) - are currently undergoing pivotal clinical trials for their lead indications, each representing multi-billion-dollar annual global market opportunities. AVIM Therapy is a bioelectronic treatment for hypertension, the leading risk factor for death worldwide, and is designed to be delivered by a pacemaker and achieve immediate, substantial and sustained reductions in blood pressure in patients with hypertensive heart disease. The Company has a strategic collaboration with Medtronic, one of the largest medical device companies in the world and the global leader in cardiac pacing therapies, for the development and commercialization of AVIM Therapy for the treatment of uncontrolled hypertension in pacemaker-indicated patients. AVIM Therapy has FDA Breakthrough Device Designations for these patients, as well as an estimated 7.7 million total patients in the U.S. with uncontrolled hypertension despite medical therapy and increased cardiovascular risk. Virtue SAB is a highly differentiated, first-of-its-kind non-coated drug delivery angioplasty balloon system designed to deliver a large liquid dose of proprietary extended-release formulation of sirolimus, SirolimusEFR™, for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. Virtue SAB has been granted Breakthrough Device Designation by the FDA for the treatment of coronary in-stent restenosis, coronary small vessel disease and below-the-knee peripheral artery disease. For further information about Orchestra BioMed, please visitwww.orchestrabiomed.com, and follow us onLinkedIn.

Investor Contact:Silas NewcombOrchestra BioMedSnewcomb@orchestrabiomed.com

Media Contact:Nina PremuticoOrchestra BioMednpremutico@orchestrabiomed.com

Frequently Asked Questions

What is the purpose of the stock options granted?

The stock options were granted as an inducement for new employees under the 2025 New Hire Inducement Plan.

How many shares were granted to new employees?

A total of 85,500 shares of common stock were granted to five new employees.

What are the flagship products of Orchestra BioMed?

The flagship products are AVIM Therapy and Virtue SAB, targeting hypertension and atherosclerotic artery disease.

What is the significance of the FDA Breakthrough Device Designation?

The designation indicates that the products have potential to address unmet medical needs and expedite development.

Last updated: Jun 3, 2026