Recent Updates
Recently added Catalysts
NXTC Positive Sentiment

NextCure to Present Phase 1b Data of NC410 in Combination with Pembrolizumab at ASCO 2024

Key Takeaway: NextCure, Inc. has announced a presentation of Phase 1b clinical trial data for NC410 in combination with pembrolizumab at the ASCO Annual Meeting in June 2024. The study focuses on patients with microsatellite stable colorectal cancer and ovarian cancer. This presentation is part of NextCure's ongoing efforts to develop innovative cancer therapies aimed at patients who do not respond to existing treatments. The clinical trial is an important step in assessing the efficacy of NC410 as a potential treatment option.
Price reaction · baseline $18.36 (2024-04-23 close) · hit after-hours · clean, no other NXTC news in the window
day 0 close
-5.9%
day 1
-15.7%
day 3 · peak
-23.5%

Market Sentiment Analysis

POSITIVE FACTORS

  • NextCure is presenting promising Phase 1b data at ASCO 2024.
  • The study evaluates NC410 in combination with pembrolizumab, potentially addressing unmet needs in colorectal and ovarian cancer.
  • The presentation will occur at a significant medical conference, which highlights the importance of the findings.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+66%
120-day peak, hindsight
Typical move
5.6%
average across 3 past catalysts
Cash runway
~6 mo
High dilution risk
Lead asset
NC318
Phase 2 · Advanced Non-small Cell Lung Cancer

Full Press Release Details

BELTSVILLE, Md., April 24, 2024 (GLOBE NEWSWIRE) --  NextCure, Inc. (Nasdaq: NXTC), a clinical-stage biopharmaceutical company committed to discovering and developing novel, first-in-class and best-in-class therapies to treat cancer, today announced that clinical trial investigator Eric S. Christenson, M.D., Assistant Professor of Oncology at Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, will present a poster on clinical data from the Phase 1b portion of a study evaluating NC410 in combination with pembrolizumab at the American Society of Clinical Oncology (ASCO) Annual Meeting from May 31 – June 4 in Chicago.
Presentation details:
Title: A phase 1b study of NC410 in combination with pembrolizumab in immune checkpoint inhibitor (ICI) naïve, and refractory microsatellite stable (MSS)/microsatellite instability-low (MSI-L) colorectal cancer (CRC) and ovarian cancer
Date and Time: June 1, 2024, 9:00 am-12:00 pm CT
Session: Poster Session: Developmental Therapeutics—Immunotherapy
Abstract Number: 2538
About NextCure, Inc.
NextCure is a clinical-stage biopharmaceutical company that is focused on advancing innovative medicines that treat cancer patients that do not respond to, or have disease progression on, current therapies, through the use of differentiated mechanisms of actions including antibody-drug conjugates, antibodies and proteins. We focus on advancing therapies that leverage our core strengths in understanding biological pathways and biomarkers, the interactions of cells, including in the tumor microenvironment, and the role each interaction plays in a biologic response. www.nextcure.com
Cautionary Statement Regarding Forward-Looking Statements
Statements made in this press release that are not historical facts are forward-looking statements. Words such as “expects,” “believes,” “intends,” “hope,” “forward” and similar expressions are intended to identify forward-looking statements. Examples of forward-looking statements in this press release include, among others, statements about NextCure’s plans, objectives, and intentions with respect to the discovery of immunomedicine targets and the discovery and development of immunomedicines. Forward-looking statements involve substantial risks and uncertainties that could cause actual results to differ materially from those projected in any forward-looking statement. Such risks and uncertainties include, among others: our limited operating history and no products approved for commercial sale; our history of significant losses; our need to obtain additional financing; risks related to clinical development, including that early clinical data may not be confirmed by later clinical results; risks that pre-clinical research may not be confirmed in clinical trials; risks related to marketing approval and commercialization; and the unproven approach to the discovery and development of product candidates based on our FIND-IO platform. More detailed information on these and additional factors that could affect NextCure’s actual results are described in NextCure’s filings with the Securities and Exchange Commission (the “SEC”), including NextCure’s most recent Form 10-K and subsequent Form 10-Q. You should not place undue reliance on any forward-looking statements. NextCure assumes no obligation to update any forward-looking statements, even if expectations change.

Frequently Asked Questions

What is the focus of NextCure, Inc.?

NextCure is focused on developing innovative cancer therapies for patients who do not respond to current treatments.

When is the ASCO Annual Meeting presentation?

The presentation will take place on June 1, 2024, from 9:00 am to 12:00 pm CT.

Who will present at the ASCO Annual Meeting?

Dr. Eric S. Christenson, an assistant professor at Johns Hopkins, will present.

What is NC410 being evaluated for?

NC410 is being evaluated in combination with pembrolizumab for colorectal and ovarian cancer.

What are the risks mentioned by NextCure?

Risks include clinical development uncertainties, financing needs, and reliance on unproven approaches.

Last updated: Apr 24, 2024