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Novartis to highlight Rhapsido® data across multiple immune-mediated diseases at EAACI Congress 2026

Key Takeaway: Novartis will present significant data on Rhapsido (remibrutinib) at the EAACI Congress 2026. Key highlights include results from the Phase III RemIND trial for chronic inducible urticaria and extension data from the Phase IIIb REMIXED trial. Additionally, a Phase II dose-response analysis for peanut allergy will be showcased, emphasizing Rhapsido's potential across various immune-mediated diseases.

Market Sentiment Analysis

POSITIVE FACTORS

  • Presentation of pivotal Phase III trial results for Rhapsido.
  • New extension data enhances understanding of chronic spontaneous urticaria.
  • Evidence of Rhapsido's potential impact on multiple immune-mediated diseases.

Full Press Release Details

• Results from Rhapsido (remibrutinib) pivotal Phase III RemIND trial, the largest study in chronic inducible urticaria, to be highlighted in late-breaker oral presentation
• New Phase IIIb REMIXED extension data in chronic spontaneous urticaria to provide additional efficacy and safety data for Rhapsido
• Phase II Rhapsido food allergy dose-response analysis in adults with IgE-mediated peanut allergy also to be presented
Basel, June 8th, 2026– Novartis will present data from 10 abstracts at the European Academy of Allergy and Clinical Immunology (EAACI) Congress 2026, spanning Rhapsido®(remibrutinib) clinical trial results and real-world evidence on patient burden and treatment experience. Highlights include two late-breaking oral presentations; the Phase III RemIND trial for Rhapsido in chronic inducible urticaria (CIndU) and extension data from the Phase IIIb REMIXED trial in chronic spontaneous urticaria (CSU).“The Rhapsido presentations at EAACI 2026 expand our understanding of BTK inhibition across multiple immune-mediated diseases and provide evidence of its potential to make a meaningful impact for patients who continue to face significant burden and limited treatment options,” said Angelika Jahreis, Global Head, Immunology Development, Novartis. “Novartis will present Rhapsido data from a long-term extension trial in chronic spontaneous urticaria, Phase III data in three types of chronic inducible urticaria, and early Phase II dose-response analysis for food allergy – together providing scientific evidence for its impact across numerous diseases.”Abstracts accepted by EAACI include:
Molecule/Disease Abstract Title Abstract Number/Presentation Details
Rhapsido®(remibrutinib)
Chronic Spontaneous Urticaria/Chronic Inducible Urticaria Remibrutinib demonstrated superior efficacy vs placebo and favorable safety in patients with chronic inducible urticaria in the phase 3 REMIND study Abstract #L-OAS03Oral PresentationJune 12, 12:36 – 12:48pm TRT
Remibrutinib demonstrated continuous efficacy and favorable safety in patients with chronic spontaneous urticaria in the randomized withdrawal period of the phase 3b REMIXED extension study Abstract #L-OAS03Oral PresentationJune 12, 12:48 – 1:00pm TRT
Remibrutinib-induced decreases in B cell biomarkers are associated with complete and sustained response in chronic spontaneous urticaria patients Abstract #FT27 (001230)Flash TalkJune 15, 1:12pm – 1:19pm TRT
Chronic Spontaneous Urticaria REASSERT: A global, prospective, non-interventional, patient-centric study evaluating the effectiveness and safety of remibrutinib and quality of life (QoL) in patients with chronic spontaneous urticaria (CSU) Abstract #FT23 (000333)Flash TalkJune 14, 6:03pm – 6:10pm TRT
Food Allergy Efficacy and safety of remibrutinib in adults with IgE-mediated peanut allergy: A Phase 2 study Abstract #TPS44 - Food allergy 03 (001345)Thematic Poster SessionJune 13, 12:00pm – 1:00pm TRT
Dose-response analysis of remibrutinib in oral food challenge outcomes among adults with IgE-mediated peanut allergy Abstract #TPS44 - Food allergy 03 (000736)Thematic Poster SessionJune 13, 12:00pm – 1:00pm TRT
Disease focus research
Chronic Spontaneous Urticaria/Chronic Inducible Urticaria Urticaria Voices: Physician-reported perspectives of chronic urticaria care and its treatment in China (UV in China) Abstract #TPS23 - Biologicals 01 (000709)Thematic Poster SessionJune 12, 12:00pm – 1:00pm TRT
Chronic Spontaneous Urticaria Urticaria Voices: Patient-reported disease burden and treatment experiences in Chronic Spontaneous Urticaria in China - A real-world evidence study (UV in China) Abstract #TPS42 - Dermatology 03 (000730)Thematic Poster SessionJune 13, 12:00pm – 1:00pm TRT
Unmet needs in treatment escalation for chronic spontaneous urticaria: Findings from the CURE Registry Abstract #FT23 (000769)Flash TalkJune 14, 6:24pm – 6:30pm TRT
Implementation of a urticaria care package in the general practitioner setting increased quality of chronic spontaneous urticaria management Abstract #FT17 (000625)Flash TalkJune 14, 12:36pm – 12:43pm TRT
About Novartis ImmunologyAt Novartis, we’re advancing bold science with the goal of bringing relief and a renewed sense of hope to people living with autoimmune diseases. Building on our legacy of first-in-class innovation across rheumatology, dermatology and allergy, and a diverse industry-leading pipeline, we’re committed to shaping what’s next in Immunology.Product InformationFor full prescribing information, including approved indications and important safety information about marketed products, please visithttps://www.novartis.com/about/products.DisclaimerThis press release contains forward-looking statements within the meaning of the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements can generally be identified by words such as “potential,” “can,” “will,” “plan,” “may,” “could,” “would,” “expect,” “anticipate,” “look forward,” “believe,” “committed,” “investigational,” “pipeline,” “launch,” or similar terms, or by express or implied discussions regarding potential marketing approvals, new indications or labeling for the investigational or approved products described in this press release, or regarding potential future revenues from such products. You should not place undue reliance on these statements. Such forward-looking statements are based on our current beliefs and expectations regarding future events, and are subject to significantly known and unknown risks and uncertainties. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those set forth in the forward-looking statements. There can be no guarantee that the investigational or approved products described in this press release will be submitted or approved for sale or for any additional indications or labeling in any market, or at any particular time. Nor can there be any guarantee that such products will be commercially successful in the future. In particular, our expectations regarding such products could be affected by, among other things, the uncertainties inherent in research and development, including clinical trial results and additional analysis of existing clinical data; regulatory actions or delays or government regulation generally; global trends toward health care cost containment, including government, payor and general public pricing and reimbursement pressures and requirements for increased pricing transparency; our ability to obtain or maintain proprietary intellectual property protection; the particular prescribing preferences of physicians and patients; general political, economic and business conditions, including the effects of and efforts to mitigate pandemic diseases; safety, quality, data integrity or manufacturing issues; potential or actual data security and data privacy breaches, or disruptions of our information technology systems, and other risks and factors referred to in Novartis AG’s current Form 20-F on file with the US Securities and Exchange Commission. Novartis is providing the information in this press release as of this date and does not undertake any obligation to update any forward-looking statements contained in this press release as a result of new information, future events or otherwise.About NovartisNovartis is an innovative medicines company. Every day, we work to reimagine medicine to improve and extend people’s lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 300 million people worldwide.Reimagine medicine with us: Visit us athttps://www.novartis.comand connect with us onLinkedIn,Facebook,X/TwitterandInstagram.# # #
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Frequently Asked Questions

What is Rhapsido used for?

Rhapsido (remibrutinib) is being studied for its efficacy in treating chronic inducible urticaria and other immune-mediated diseases.

When will Novartis present Rhapsido data?

Novartis will present Rhapsido data at the EAACI Congress 2026.

What trials will be highlighted at the EAACI Congress?

The Phase III RemIND trial and Phase IIIb REMIXED trial data will be highlighted.

What is the focus of the Phase II analysis?

The Phase II analysis focuses on the dose-response for Rhapsido in adults with IgE-mediated peanut allergy.

Last updated: Jun 8, 2026