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Intellia Therapeutics to Report Topline Data from Global Phase 3 HAELO Clinical Trial of Lonvoguran Ziclumeran in Hereditary Angioedema on April 27, 2026

Key Takeaway: Intellia Therapeutics announced it will report topline data from its Phase 3 HAELO clinical trial for lonvoguran ziclumeran in hereditary angioedema on April 27, 2026. This marks the world's first Phase 3 readout for an in vivo CRISPR gene editing candidate. The company will host a webcast to discuss the findings, showcasing its commitment to transparency.

Market Sentiment Analysis

POSITIVE FACTORS

  • First Phase 3 readout for an in vivo CRISPR gene editing candidate.
  • Potentially curative treatments for hereditary angioedema.
  • Webcast to discuss data indicates transparency and engagement.

Full Press Release Details

• World’s first Phase 3 readout for anin vivoCRISPR gene editing candidate
• Company to host webcast to discuss data at 8:00 a.m. ET on April 27, 2026
CAMBRIDGE, Mass., April 24, 2026 (GLOBE NEWSWIRE) --Intellia Therapeutics, Inc.(Nasdaq: NTLA), a leading biopharmaceutical company focused on revolutionizing medicine leveraging CRISPR gene editing and other core technologies, today announced the company will report topline clinical data from its global Phase 3 HAELO clinical trial of lonvoguran ziclumeran (lonvo-z) in hereditary angioedema (HAE) on Monday, April 27, 2026 and will host a webcast at 8:00 a.m. ET to discuss the data.
To join the webcast, please visit the Events page of the Investors & Media section on Intellia’s website atintelliatx.com. A replay of the webcast will be available for approximately 90 days.
About Intellia TherapeuticsIntellia Therapeutics, Inc. (Nasdaq: NTLA) is a leading clinical-stage biopharmaceutical company focused on revolutionizing medicine leveraging CRISPR gene editing and other core technologies. The company’s mission is to transform the lives of people with severe diseases by developing and commercializing potentially curative treatments. With deep scientific, technical and clinical development experience, Intellia aims to reset the standard for medicine by durably treating the root causes of disease. Learn more atintelliatx.comand follow us@intelliatx.
Investor Contact:Jason FredetteVice President, Investor Relations and Corporate CommunicationsIntellia Therapeutics, Inc.jason.fredette@intelliatx.com

Media Contact:Mike TattoryVice PresidentLifeSci Communicationsmtattory@lifescicommunications.com

Frequently Asked Questions

What is the HAELO clinical trial?

The HAELO clinical trial is a global Phase 3 study evaluating lonvoguran ziclumeran for hereditary angioedema.

When will Intellia report the trial data?

Intellia will report topline data from the trial on April 27, 2026.

How can I join the webcast?

You can join the webcast by visiting the Events page on Intellia's website.

What is lonvoguran ziclumeran?

Lonvoguran ziclumeran is a CRISPR gene editing candidate being tested for hereditary angioedema.

Last updated: Apr 24, 2026