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NeOnc Executes Sub-License Agreement With Quazar Investment

Key Takeaway: NeOnc Technologies Holdings, Inc. has signed a Sub-License Agreement with Quazar Investment, marking a significant step in their strategic transaction. This agreement covers the UAE and MENA region for their drug candidates NEO100 and NEO212. The partnership aims to raise $50 million for clinical trials and infrastructure development. However, the transaction's completion depends on fulfilling several conditions within 120 days.
Price reaction · baseline $4.84 (2025-07-22 close) · hit pre-market · 2 other NTHI headline(s) in the window, move may be shared
day 0 close
+2.3%

Market Sentiment Analysis

POSITIVE FACTORS

  • NeOnc has executed a Sub-License Agreement with Quazar Investment.
  • The agreement is a critical milestone towards a $50 million partnership.
  • NEO100 and NEO212 are advancing in clinical trials under FDA Fast-Track status.
  • The partnership aims to enhance market liquidity and attract institutional capital.

CONCERNS & RISKS

  • The closing of the transaction is subject to several remaining conditions.
  • There is uncertainty regarding the finalization of the agreement with Quazar.
  • Future events may differ from current expectations, as stated in forward-looking statements.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Cash runway
~1 mo
High dilution risk
Lead asset
Perillyl alcohol
Phase 1 · Glioblastoma Multiforme

Full Press Release Details

NeOnc Technologies Holdings, Inc. ( NTHI ), a clinical-stage biotechnology company advancing transformative treatments for brain and central nervous system cancers, today announced it has achieved a key milestone toward closing its previously announced strategic transaction with Quazar Investment: execution and transfer of a Sub-License Agreement from NeOnc to its Abu Dhabi onshore operating subsidiary, NuroCure. The Sub-License covers the UAE and the wider GCC and MENA region with respect to NEO100 and NEO212, pursuant to NeOnc’s license from USC Stevens Center for Innovation.
On July 8, 2025, NeOnc announced a non-binding term sheet to participate in the contemplated $50 million equity investment and MENA region expansion with Quazar. This licensing agreement marks the second of five required conditions in the transaction closing process.
Amir Heshmatpour
“We’ve strategically aligned the timing of our Russell Microcap Index inclusion with the Quazar partnership to attract institutional capital, drive passive fund flows, and enhance market liquidity,” said Amir Heshmatpour, Executive Chairman & President of NeOnc Technologies Holdings, Inc.
“It’s a clear stamp of credibility and a core pillar of our broader capital markets strategy. Completing the Sub-License Agreement is a critical milestone that brings us one step closer to unlocking the full potential of our $50 million partnership at $25 dollars per share with Quazar delivering long-term value to our shareholders and advancing life-saving therapies for patients across the MENA region.”
“It feels like NeOnc is undergoing a major transformation from a clinical-stage biotech to a global brain cancer platform,” added Dr. Ishwar Puri, Senior Vice President, Research & Innovation, University of Southern California.
Dr. Ishwar Puri
Under the non-binding term sheet, Quazar intends to lead a capital formation round of up to $50 million, priced at $25 per share. The proposed structure allocates 70% of proceeds to the acquisition of NeOnc common stock, with 30% earmarked for launching clinical trials and building infrastructure across the UAE and broader MENA region.
To complete the transaction, NeOnc must satisfy the remaining conditions within 120 days, including:
• Legal formation of NuroMENA and NuroCure in Abu Dhabi.
• Finalization of offering documents, including subscription agreements and a shareholder agreement.
• Approval of a comprehensive two-year business plan and budget, outlining operational and clinical milestones.
The closing remains subject to these conditions and the successful completion of the capital formation process.
ABOUT NEONC TECHNOLOGIES HOLDINGS, INC.
NeOnc Technologies Holdings, Inc. is a clinical-stage life sciences company focused on the development and commercialization of central nervous system therapeutics that are designed to address the persistent challenges in overcoming the blood-brain barrier. The company’s NEO™ drug development platform has produced a portfolio of novel drug candidates and delivery methods with patent protections extending to 2038. These proprietary chemotherapy agents have demonstrated positive effects in laboratory tests on various types of cancers and in clinical trials treating malignant gliomas. NeOnc’s NEO100™ and NEO212™ therapeutics are in Phase II human clinical trials and are advancing under FDA Fast-Track and Investigational New Drug (IND) status. The company has exclusively licensed an extensive worldwide patent portfolio from the University of Southern California consisting of issued patents and pending applications related to NEO100, NEO212, and other products from the NeOnc patent family for multiple uses, including oncological and neurological conditions. For more about NeOnc and its pioneering technology, visit neonc.com .
Important Cautions Regarding Forward Looking Statements
This press release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements can be identified by terminology such as “may,” “will,” “should,” “intend,” “expect,” “plan,” “budget,” “forecast,” “anticipate,” “believe,” “estimate,” “predict,” “potential,” “continue,” “evaluating,” or similar words. Statements that contain these words should be read carefully, as they discuss our future expectations, projections of future results of operations or financial condition, or other forward-looking information.
Examples of forward-looking statements include, among others, statements regarding whether a definitive agreement will be reached with Quazar. These statements reflect our current expectations based on information available at this time, but future events may differ materially from those anticipated.
The “Risk Factors” section of our most recent Annual Report on Form 10-K filed with the Securities and Exchange Commission, along with other cautionary language in that report or in our subsequent filings, outlines important risks and uncertainties. These may cause our actual results to differ materially from the forward-looking statements herein, including but not limited to the failure to finalize the agreement with Quazar, modifications to its terms, or alternative uses of proceeds.
We assume no obligation to revise or update any forward-looking statements, whether as a result of new information, future developments, or otherwise, except as required by applicable securities laws and regulations.
“NEO100” and NEO “212” are registered trademarks of NeOnc Technologies Holdings, Inc.

Frequently Asked Questions

What is the purpose of the Sub-License Agreement?

The Sub-License Agreement allows NeOnc to expand its drug candidates NEO100 and NEO212 in the UAE and MENA region.

What is the financial goal of the partnership with Quazar?

The partnership aims to raise $50 million for clinical trials and infrastructure development.

What are the next steps for NeOnc after this agreement?

NeOnc must fulfill several conditions within 120 days to complete the transaction.

What is the status of NEO100 and NEO212?

NEO100 and NEO212 are currently in Phase II human clinical trials under FDA Fast-Track status.

Last updated: Jul 23, 2025