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NeuroSense to Present PARADIGM Data at the American Academy of Neurology Annual Meeting April 16, 2024

Key Takeaway: NeuroSense Therapeutics Ltd. announced that it will present data from its PARADIGM Phase 2 study of PrimeC at the American Academy of Neurology Annual Meeting on April 16, 2024. Under the guidance of lead author Dr. Merit Cudkowicz, the presentation will focus on the drug's success in meeting primary and secondary endpoints in treating Amyotrophic Lateral Sclerosis (ALS). NeuroSense emphasizes its commitment to developing treatments for severe neurodegenerative diseases, which currently have limited therapeutic options. The company faces risks and uncertainties associated with the development and potential approval of PrimeC and other future trials.

Market Sentiment Analysis

POSITIVE FACTORS

  • NeuroSense is presenting promising Phase 2 data on PrimeC, suggesting significant progress.
  • The presentation highlights meeting both primary and secondary endpoints in the trial.
  • The focus on Alzheimer’s, ALS, and Parkinson’s indicates addressing major unmet medical needs.

CONCERNS & RISKS

  • The press release included forward-looking statements with substantial risks and uncertainties.
  • There are potential delays in reporting results and regulatory interactions.
  • The future effectiveness of PrimeC remains uncertain until further trials are completed.

Full Press Release Details

Emerging Science (Late-Breaker Equivalent) Abstract To Be Presented At 5:30PM Local Time Highlights Phase 2 PARADIGM Outcomes
CAMBRIDGE, Mass., April 12, 2024 /PRNewswire/ -- NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) ("NeuroSense"), a company developing novel treatments for severe neurodegenerative diseases, announces lead author Merit Cudkowicz, Chair of Neurology at Massachusetts General Hospital, and Julieanne Dorn Professor of Neurology at Harvard Medical School, will be presenting data from the PARADIGM Phase 2 study of PrimeC during an Emerging Science session (equivalent to Late Breaker) at the American Academy of Neurology Annual Meeting.
The presentation, titled, 'PrimeC, An Oral Candidate for Amyotrophic Lateral Sclerosis, Meets Primary and Secondary Endpoints in the Phase 2b PARADIGM Trial.' Dr. Cudkowicz's presentation will be held on April 16, 2024 at 5:30PM local time. The meeting is being held April 13-18 at the Colorado Convention Center in Denver, Colorado.
NeuroSense Therapeutics, Ltd. is a clinical-stage biotechnology company focused on discovering and developing treatments for patients suffering from debilitating neurodegenerative diseases. NeuroSense believes that these diseases, which include amyotrophic lateral sclerosis (ALS), Alzheimer's disease and Parkinson's disease, among others, represent one of the most significant unmet medical needs of our time, with limited effective therapeutic options available for patients to date. Due to the complexity of neurodegenerative diseases and based on strong scientific research on a large panel of related biomarkers, NeuroSense's strategy is to develop combined therapies targeting multiple pathways associated with these diseases.
Forward-Looking Statements
This press release contains "forward-looking statements" that are subject to substantial risks and uncertainties. All statements, other than statements of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press release may be identified by the use of words such as "anticipate," "believe," "contemplate," "could," "estimate," "expect," "intend," "seek," "may," "might," "plan," "potential," "predict," "project," "target," "aim," "should," "will" "would," or the negative of these words or other similar expressions, although not all forward-looking statements contain these words. Forward-looking statements are based on NeuroSense Therapeutics' current expectations and are subject to inherent uncertainties, risks and assumptions that are difficult to predict and include statements regarding PrimeC as a potential treatment for people with ALS, the timing for release of additional results from PARADIGM clinical trial, the cash runway of the Company, the timing of a Phase 2 trial for Alzheimer's disease and patient enrollment regarding a Phase 3 pivotal ALS trial of PrimeC. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate. The future events and trends may not occur and actual results could differ materially and adversely from those anticipated or implied in the forward looking statements. These risks include unexpected R&D costs or operating expenses, a delay in the reporting of additional results from PARADIGM clinical trial, the timing of expected regulatory and business milestones, risks associated with meeting with the FDA to determine the best path forward following the results from PARADIGM clinical trial, including a delay in any such meeting, a delay in patient enrollment for a Phase 2 trial for Alzheimer's disease; the potential for PrimeC to safely and effectively target AD; preclinical and clinical data for PrimeC; the uncertainty regarding outcomes and the timing of current and future clinical trials; timing for reporting data; the development and commercial potential of any product candidates of the company; and other risks and uncertainties set forth in NeuroSense's filings with the Securities and Exchange Commission (SEC). You should not rely on these statements as representing our views in the future. More information about the risks and uncertainties affecting the Company is contained under the heading "Risk Factors" in the Annual Report on Form 20-F filed with the Securities and Exchange Commission on April 4, 2024. Forward-looking statements contained in this announcement are made as of this date, and NeuroSense Therapeutics Ltd. undertakes no duty to update such information except as required under applicable law.

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Frequently Asked Questions

What is the PARADIGM Phase 2 study focused on?

The PARADIGM Phase 2 study is focused on evaluating PrimeC as a potential treatment for amyotrophic lateral sclerosis (ALS).

When will the study results be presented?

Results from the PARADIGM Phase 2 study will be presented on April 16, 2024, at 5:30 PM local time.

Who is the lead author of the study presentation?

The lead author is Dr. Merit Cudkowicz, Chair of Neurology at Massachusetts General Hospital.

Where is the American Academy of Neurology meeting being held?

The meeting is taking place at the Colorado Convention Center in Denver, Colorado.

What is NeuroSense Therapeutics focused on?

NeuroSense Therapeutics specializes in developing treatments for severe neurodegenerative diseases.

Last updated: Apr 12, 2024