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FORM 51-102F3 MATERIAL CHANGE REPORT Item 1: Name and Address of Company NervGen Pharma Corp. (" NervGen " or the " Company ") 112-970 Burrard Street Unit 1290 Vancouver, BC V6Z 2R4 Item 2: Date of Material Change

Key Takeaway: NervGen Pharma Corp. has announced a public offering of 24 million common shares at $2.50 each, aiming to raise about $60 million for clinical studies on NVG-291 and general corporate expenses. The offering includes warrants for additional shares at an exercise price of $3.68. PFP Biosciences, a company insider, participated in this offering, reflecting a supportive investment stance. The board approved the offering without material dissent, aiming for an expedited closing for business reasons.

Market Sentiment Analysis

POSITIVE FACTORS

  • NervGen Pharma raised approximately US$60 million through an underwritten public offering.
  • The funds will support the advancement of NVG-291 through clinical studies.
  • Participation of an insider, PFP Biosciences, indicates confidence in the offering.

Full Press Release Details

MATERIAL CHANGE REPORT
NervGen Pharma Corp. ("NervGen"
112-970 Burrard Street
Vancouver, BC V6Z 2R4
A news release announcing the material
change was disseminated on May 21, 2026 through Newsfile Corp's distribution network, and a copy was subsequently filed on
NervGen's SEDAR+ profile at www.sedarplus.ca.
On May 21, 2026 the Company announced
the pricing of an underwritten public offering (the "Offering") of 24,000,000 common shares of the Company (the "Common
Shares") and accompanying warrants to purchase up to 24,000,000 Common Shares (the "Warrants"). The Common
Shares are being sold at a public offering price of US$2.50 per Common Share and Warrant (the "Offering Price"). Each
Warrant has an exercise price of US$3.68 per Common Share, and will be immediately exercisable from the date of issuance, and will expire
five years from the date of issuance.
The gross proceeds from the Offering,
before deducting underwriting discounts and commissions and offering expenses and excluding any proceeds from the exercise of the Warrants,
is approximately US$60.0 million.
On May 21, 2026, the Company announced
the pricing of the Offering of 24,000,000 Common Shares and Warrants at the Offering Price. Each Warrant has an exercise price of US$3.68
per Common Share, and will be immediately exercisable from the date of issuance, and will expire five years from the date of issuance
The gross proceeds from the Offering,
before deducting the underwriting discounts and commissions and offering expenses and excluding any proceeds from the exercise of the
Warrants, is approximately US$60.0 million.
Leerink Partners LLC and TD Securities
(USA) LLC acted as joint bookrunning managers for the Offering.
NervGen intends to use the net proceeds
from the Offering, together with its existing cash and cash equivalents, to advance NVG-291 through clinical studies and for general corporate
and working capital purposes.
PFP Biosciences Holdings LLC ("PFP
Biosciences"), an insider of the Company, participated in the Offering. Such participation constitutes a "related party
transaction" as defined under Multilateral Instrument 61-101 - Protection of Minority Security Holders in Special Transactions ("MI
61-101") and TSX Venture Exchange Policy 5.9. The Company is exempt from the formal valuation requirement and minority shareholder
approval requirement pursuant to sections 5.5(a) and 5.7(1)(a) of MI 61-101, respectively, as the fair market value of the securities
to be issued to PFP Biosciences and the consideration paid by PFP Biosciences does not exceed 25% of the Company's market capitalization.
Prior to the Offering, PFP Biosciences
owned and controlled 14,688,673 Common Shares, representing 17.87% of the issued and outstanding Common Shares and 7,344,335 Warrants.
Immediately following the Offering, PFP
Biosciences owned and controlled 15,488,673 Common Shares, representing 14.58% of the issued and outstanding Common Shares, and 8,144,335
Warrants. The Warrants held by PFP Biosciences contain a restriction on exercise of the Warrants that limits the holder thereof from owning
more than 19.99% of the Common Shares of the Company.
PFP Biosciences acquired the Common Shares
and Warrants for investment purposes and may acquire or dispose of securities of the company in the future in accordance with applicable
The Offering was approved by the board
of directors of the Company and a pricing committee of the board of directors, and no materially contrary view was expressed nor was there
any material disagreement in the approval process adopted by the directors. The Company did not file a material change report more than
21 days before the expected closing of the Offering as the details of the Offering and the participation therein by PFP Biosciences was
not settled until shortly prior to closing of the Offering and the Company wished to close on an expedited basis for sound business reasons.
Keith Vendola, Chief Financial Officer
112-970 Burrard Street
Vancouver, BC V6Z 2R4

Frequently Asked Questions

What was announced by NervGen on May 21, 2026?

NervGen announced the pricing of a public offering of 24,000,000 Common Shares.

What is the exercise price of the Warrants?

The Warrants have an exercise price of US$3.68 per Common Share.

How much gross proceeds is expected from the Offering?

The gross proceeds are approximately US$60.0 million.

Who managed the Offering for NervGen?

Leerink Partners LLC and TD Securities (USA) LLC managed the Offering.

What is PFP Biosciences' stake in NervGen post-Offering?

PFP Biosciences owns 14.58% of the issued and outstanding Common Shares now.

Last updated: May 21, 2026