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MEREO LAWSUIT ALERT: Bragar Eagel & Squire, P.C. Announces that a Class Action Lawsuit Has Been Filed Against Mereo BioPharma Group plc and Encourages Investors to Contact the Firm

Key Takeaway: A class action lawsuit has been initiated against Mereo BioPharma Group plc by Bragar Eagel & Squire, P.C. on behalf of investors who acquired Mereo American Depositary Shares between June 5, 2023, and December 26, 2025. The lawsuit alleges that the company misled investors regarding the expected results from the Phase 3 ORBIT and COSMIC studies for setrusumab in Osteogenesis Imperfecta (OI). Following the recent announcement that the studies did not meet their primary endpoints, Mereo's stock price saw a significant decline of over 87.7% within a few days. Investors have until April 6, 2026, to apply to be appointed as lead plaintiffs in the case.

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CONCERNS & RISKS

  • A class action lawsuit has been filed against Mereo BioPharma due to alleged misleading statements.
  • Mereo's Phase 3 studies for setrusumab failed to meet primary endpoints, affecting investor confidence.
  • The company’s stock price plummeted by over 87.7% following the release of disappointing study results.

Full Press Release Details

Bragar Eagel & Squire, P.C. Litigation Partner Brandon Walker Encourages Investors Who Suffered Losses In Mereo (MREO) To Contact Him Directly To Discuss Their Options
If you purchased or acquired Mereo American Depositary Shares (“ADS”) between June 5, 2023, and December 26, 2025 and would like to discuss your legal rights, call Bragar Eagel & Squire partner Brandon Walker or Melissa Fortunato directly at (212) 355-4648.
Click here to participate in the action.
NEW YORK, Feb. 05, 2026 (GLOBE NEWSWIRE) --
Bragar Eagel & Squire, P.C., a nationally recognized stockholder rights law firm, announces that a class action lawsuit has been filed against Mereo BioPharma Group plc (“Mereo” or the “Company”) (NASDAQ:MREO) in the United States District Court for the Southern District of New York on behalf of all persons and entities who purchased or otherwise acquired Mereo American Depositary Shares (“ADS”) between June 5, 2023, and December 26, 2025, both dates inclusive (the “Class Period”). Investors have until April 6, 2026 to apply to the Court to be appointed as lead plaintiff in the lawsuit.
According to the complaint, defendants provided investors with material information concerning their expected results for the Phase 3 ORBIT and COSMIC studies for setrusumab in Osteogenesis Imperfecta (OI). Defendants’ statements included, among other things, confidence in setrusumab’s ability to ultimately reduce the annualized fracture rates of the tested patients and in the study itself to put setrusumab in an opportunity to succeed in reaching statistical significance of this key endpoint. The complaint continues that defendants provided these positive statements to investors while, at the same time, disseminating false and materially misleading statements and/or concealing material adverse facts concerning the true state of the Phase 3 ORBIT and COSMIC programs; neither of which hit its primary endpoints of reducing annualized clinical fracture rate compared to the placebo or bisphosphonate control groups, respectively. Such statements absent these material facts caused Plaintiff and other shareholders to purchase Mereo’s ADS at artificially inflated prices.
The complaint alleges that on December 29, 2025, Mereo issued a press release announcing that neither the ORBIT nor the COSMIC Phase 3 studies met its primary endpoint of reduction in annualized clinical fracture rate (“AFR”) compared to placebo or bisphosphonates, respectively, despite improved bone mineral density (“BMD”). On this news, the price of Mereo’s ADS declined from $2.31 per share on December 26, 2025, to $0.29 per share on December 29, 2025, a decline of more than 87.7%.
If you purchased or otherwise acquired Mereo shares and suffered a loss, are a long-term stockholder, have information, would like to learn more about these claims, or have any questions concerning this announcement or your rights or interests with respect to these matters, please contact Brandon Walker or Melissa Fortunato by email at investigations@bespc.com, telephone at (212) 355-4648, or by filling out this contact form. There is no cost or obligation to you.
About Bragar Eagel & Squire, P.C.:
Bragar Eagel & Squire, P.C. is a nationally recognized law firm with offices in New York, South Carolina, and California. The firm represents individual and institutional investors in securities,
derivative, and commercial litigation as well as individuals in consumer protection and data privacy litigation. The firm has a nationwide practice and routinely handles cases in both federal and state courts. For more information about the firm, please visit www.bespc.com.  Attorney advertising.  Prior results do not guarantee similar outcomes.
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Contact Information:
Bragar Eagel & Squire, P.C.
Brandon Walker, Esq.
Melissa Fortunato, Esq.

Tags

Mereo BioPharma Group plc
Bragar Eagel & Squire

Frequently Asked Questions

What is the class action lawsuit against Mereo about?

The lawsuit alleges Mereo provided misleading information about clinical trial results.

Who can participate in the Mereo class action lawsuit?

Individuals who acquired Mereo ADS between June 5, 2023, and December 26, 2025.

How can I contact Bragar Eagel & Squire for more information?

You can call (212) 355-4648 or email investigations@bespc.com.

What deadline is set for lead plaintiff applications?

The deadline to apply as lead plaintiff is April 6, 2026.

What happened to Mereo's ADS price after the trial results were released?

The ADS price dropped from $2.31 to $0.29, a decline over 87.7%.

Last updated: Feb 5, 2026